Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Molecular mechanisms regulating the expression of lymphangiogenic factors podoplanin and Prox1 in differentiated thyroid carcinomas. Searching for changes in the signaling paths associated with the migration and invasiveness of cancer cells.

2012/07/B/NZ5/02444

Keywords:

thyroid cancer lymphangiogenesis metastasis podoplanin Prox1

Descriptors:

  • NZ5_1: Etiology of human diseases
  • NZ2_12: Other related subjects
  • NZ3_14: Other related subjects

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Centrum Medyczne Kształcenia Podyplomowego

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Barbara Czarnocka 

Number of co-investigators in the project: 6

Call: OPUS 4 - announced on 2012-09-15

Amount awarded: 995 480 PLN

Project start date (Y-m-d): 2013-06-19

Project end date (Y-m-d): 2016-12-18

Project duration:: 42 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Inkubator z wytrząsaniem ThermoScientific MaxQTM4450 z wyposażeniem –platforma uniwersalna rozmiar 26x33, i cztery uchwyty na kolby Erlenmeyera o różnej objętości.
  2. Multiporator, do organizmów eukariotycznych, bakterii i drożdży (47 000 PLN)
  3. Miniwirówka Spectrafuge Biosan.
  4. EVETMNanoEnTek automatic cell counter automatyczny licznik komórek z zestawem komór do liczenia.

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (6)
  1. The role of podoplanin in the biology of differentiated thyroid cancers.
    Authors:
    Rudzińska M, Gaweł D, Sikorska J, Karpińska KM, Kiedrowski M, Stępień T, Marchlewska M, Czarnocka B.
    Academic press:
    Plos One (rok: 2014, tom: 9 (5), strony: 10.1371/journal.pone.0096541), Wydawca: www.plosone.org
    Status:
    Published
  2. The role of prospero homeobox 1 (PROX1) expression in follicular thyroid carcinoma cells
    Authors:
    Magdalena Rudzinska1, Joanna K. Ledwon1, Damian Gawel1, Justyna Sikorska1 and Barbara Czarnocka1
    Academic press:
    ONCOTARGET (rok: 2017, tom: 8, strony: 114136-114155), Wydawca: www.impactjournals.com/oncotarget
    Status:
    Published
    DOI:
    10.18632/oncotarget.23167 - link to the publication
  1. The role of podoplanin in the biology of differentiated thyroid cancers.
    Authors:
    Karpińska K., Rudzińska M., Gaweł D., Kiedrowski M., Stępień T., Marchlewska M., Domek H., Czarnocka B.
    Conference:
    16th European Congress of Endocrinology (ECE 2014), Wrocław (rok: 2014, ), Wydawca: Endocrine Abstracts May 2014 Volume 35 ISSN 1479-6848 (online)
    Data:
    konferencja 3-7 May
    Status:
    Published
  2. Funkcja homeotycznego czynnika transkrypcyjnego PROX1 w przerzutowaniu raka pęcherzykowego tarczycy; powiązanie między PROX1 i ścieżką kinazy AKT
    Authors:
    Rudzińska M, Ledwoń A, Karpińska K, Macios M, Sikorska J, Czarnocka B.
    Conference:
    V Zjazd Polskiego Towarzystwa Tyreologicznego, Poznań (rok: 2015, ), Wydawca: BioMed Central
    Data:
    konferencja 3-5 września
    Status:
    Published
  3. Podoplanin a lymphangiogenesis regulator and its role in differentiated thyroid cancer biology
    Authors:
    Magdalena Rudzińska, Damian Gawel, Kamila Maria Karpinska, Miroslaw Kiedrowski, Katarzyna Arczewska, Justyna Sikorska, Tomasz Stepien, Magdalena Marchlewska Stępien, Barbara Czarnocka
    Conference:
    16th International Congress of Endocrinology and the Endocrine Society's , Chicago (rok: 2014, ), Wydawca: press.endocrine.org
    Data:
    konferencja 21-24 June
    Status:
    Published
  4. The role of transcription factor Prospero homeobox 1 in the biology of the differentiated thyroid cancer
    Authors:
    Rudzińska M., Karpińska K.,Gaweł D., Kiedrowski M., Stępień T., Marchlewska M., Domek H., Czarnocka B.
    Conference:
    16th European Congress of Endocrinology (ECE 2014) Wrocław (rok: 2014, ), Wydawca: Endocrine Abstracts May 2014 Volume 35 ISSN 1479-6848 (online), p.391, Poster P1131
    Data:
    konferencja 3-7 May 2014
    Status:
    Published
  5. Prox1 transcription factor is differentially expressed in thyroid cancer and contributes to the regulation of invasion and migration of thyroid cancer cells
    Authors:
    Rudzińska M, Karpińska K, Gaweł D, Kiedrowski M, Stepien T, Marchlewska M, Krasuska W, Ledwon J, Macios M, Czarnocka B.
    Conference:
    17th European Congress of Endocrinology , Dublin (rok: 2015, ), Wydawca: Endocrine Abstracts May 2015 Volume 37
    Data:
    konferencja 16-20 May
    Status:
    Published
  6. The role of trascription factor- Prospero homeobox 1 (Prox1) in the biology of differentiated thyroid tumors
    Authors:
    Rudzińska M, Karpińska K, Krasuska W, Czarnocka B.
    Conference:
    7th International Conference of Contemporary Oncology, Poznań (rok: 2015, ), Wydawca: Termedia
    Data:
    konferencja 25-27 March
    Status:
    Published