Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Immune response profile assessment after stereotactic radiotherapy for lung cancer.

2012/07/B/NZ5/00587

Keywords:

Radiation therapy immunology immunotherapy lung cancer neoplasm oncology SBRT cytokine flow cytometry lymphocyte

Descriptors:

  • NZ5_7: Human disease treatment
  • NZ6_2: Clinical immunology
  • NZ4_4: Pathophysiology

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Gdański Uniwersytet Medyczny, Wydział Lekarski

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Renata Zaucha 

Number of co-investigators in the project: 3

Call: OPUS 4 - announced on 2012-09-15

Amount awarded: 254 985 PLN

Project start date (Y-m-d): 2013-07-03

Project end date (Y-m-d): 2016-07-02

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Przenośny komputer osobisty - laptop (3 500 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (6)
  1. Prospective evaluation of anxiety, depression and the quality of life in medically inoperable early stage non-small cell lung cancer patients treated with stereotactic ablative radiotherapy.
    Authors:
    Jacek Rutkowski, Magdalena Szymanik, Maciej Blok, Joanna Kozaka, Renata Zaucha,
    Academic press:
    Reports of Practical Oncology and Radiotherapy (rok: 2017, tom: 22(3), strony: 217-221), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.rpor.2017.01.002. - link to the publication
  2. Evaluation of peripheral blood T lymphocyte surface activation markers and transcription factors in patients with early stage non-small cell lung cancer.
    Authors:
    Jacek Rutkowski, Marta Cyman, Tomasz Ślebioda, Kamila Bemben, Aleksandra Rutkowska, Marcin Gruchała, Zbigniew Kmieć, Agnieszka Pliszka and Renata Zaucha
    Academic press:
    Cell Immunol (rok: 2017, tom: 322, strony: 26-33), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.cellimm.2017.09.007 - link to the publication
  3. Systemic immune response changes after stereotactic ablative radiotherapy (SABR) - a prospective study in early lung cancer patients
    Authors:
    Jacek Rutkowski, Tomasz Ślebioda, Zbigniew Kmieć, Renata Zaucha
    Academic press:
    Pol Arch Intern Med (rok: 2017, tom: 127(4), strony: 245-253), Wydawca: John Wiley & Sons
    Status:
    Published
    DOI:
    10.20452/pamw.3997 - link to the publication
  1. Changes in immune response profile after stereotactic radiotherapy of lung cancer
    Authors:
    TOMASZ ŚLEBIODA, JACEK RUTKOWSKI, RENATA ZAUCHA.
    Conference:
    XLVIII Sympozjum Polskiego Towarzystwa Histochemików i Cytochemików: od MAKRO do NANO. Nowe horyzonty i nowe możliwości w naukach podstawowych i klinicznych (rok: 2014, ), Wydawca: bd.
    Data:
    konferencja 3-6 września 2014
    Status:
    Published
  2. Immune response profile assessment after stereotactic radiotherapy for lung cancer
    Authors:
    JACEK RUTKOWSKI, TOMASZ J. ŚLEBIODA, RENATA ZAUCHA.
    Conference:
    EUROPEAN SOCIETY FOR RADIOTHERAPY AND ONCOLOGY 3RD ESTRO FORUM 2015 BARCELONA (rok: 2015, ), Wydawca: Elsevier
    Data:
    konferencja 24-28.04.2015
    Status:
    Published
  3. Ocena ekspresji antygenów powierzchniowych (CD4, CD8, CD25, CD28, PD-1, CTLA-4) oraz czynników transkrypcyjnych (T-bet, ROR-yt, Fox-P3, GATA-3) limfocytów T w krwi obwodowej u chorych na wczesną postać niedrobnokomórkowego raka płuca
    Authors:
    Jacek Rutkowski, Marta Cyman, Tomasz Ślebioda, Kamila Bemben, Renata Zaucha
    Conference:
    IV Kongres Onkologii Polskiej (rok: 2016, ), Wydawca: nd
    Data:
    konferencja 12-15/10/2016
    Status:
    Published
  4. Elevated fraction of CTLA-4(+) and PD-1(+) T cells in peripheral blood with stimulation of Th1, Th2 and Th17 type immune response after stereotactic radiotherapy for early lung cancer – a prospective study
    Authors:
    Jacek Rutkowski, Tomasz Ślebioda, Renata Zaucha
    Conference:
    ESMO 2016 Congress (rok: 2016, ), Wydawca: Oxford University Press
    Data:
    konferencja 7-11.październik 2016
    Status:
    Published
  5. Ocena ekspresji powierzchniowych i wewnątrz- komórkowych antygenów limfocytów T u cho- rych na raka płuca otrzymujących stereotaktycz- ną radioterapię
    Authors:
    Jacek Rutkowski, Tomasz Ślebioda, Renata Zaucha
    Conference:
    Kongres Onkologii Polskiej (rok: 2016, ), Wydawca: nd
    Data:
    konferencja 12-15/10/2016
    Status:
    Published
  6. Peripheral blood CTLA-4(+) and PD-1(+) T-cells changes and their impact on overall survival after stereotactic body radiotherapy (SABRT) for early stage non-small cell lung cancer (NSCLC)
    Authors:
    Rutkowski J, Ślebioda T, Kmieć Z, Zaucha R
    Conference:
    13th Central European Oncological Congress Best of ASCO (rok: 2017, ), Wydawca: nd
    Data:
    konferencja 21-24/06/2017
    Status:
    Published