Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Physico-chemical and biochemical studies of selected nitrogen (II) oxide conveyors. The relationship between molecular and electronic structure, and biological activity of nitrosyl iron complexes.

2012/07/D/ST4/02177

Keywords:

nitrosyl complex nitric oxide spectroscopy ESR UV-VIS IR NMR crystal structure

Descriptors:

  • ST4_13: Solid-state chemistry, surface physicochemistry
  • ST4_3: Molecular architecture and structure
  • NZ1_3: Biophysics

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Instytut Chemii i Techniki Jądrowej (IChTJ)

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Hanna Lewandowska-Siwkiewicz 

Number of co-investigators in the project: 7

Call: SONATA 4 - announced on 2012-09-15

Amount awarded: 498 000 PLN

Project start date (Y-m-d): 2013-06-27

Project end date (Y-m-d): 2016-06-26

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Zestaw do pracyw warunkach beztlenowych, z komorą anaerobową (87 000 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  1. Formation of glutathionyl dinitrosyl iron complexes protects against iron genotoxicity
    Authors:
    Hanna Lewandowska, Jarosław Sadło, Sylwia Męczyńska, Tomasz M Stępkowski, Grzegorz Wójciuk, Marcin Kruszewski
    Academic press:
    Dalton Transactions (rok: 2015, tom: 44(28), strony: 12640-12652), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/C5DT00927H - link to the publication
  2. LDL dinitrosyl iron complex acts as an iron donor in mouse macrophages
    Authors:
    Hanna Lewandowska, Tomasz M. Stępkowski, Sylwia Męczyńska-Wielgosz, Katarzyna Sikorska, Jarosław Sadło, Jakub Dudek, Marcin Kruszewski
    Academic press:
    Journal of Inorganic Biochemistry (rok: 2018, tom: 188, strony: 29-37), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jinorgbio.2018.08.004 - link to the publication
  3. LDL dinitrosyl iron complex: A new transferrin‐independent route for iron delivery in hepatocytes
    Authors:
    Hanna Lewandowska*, Sylwia Męczyńska, Katarzyna Sikorska, Jarosław Sadło, Jakub Dudek, Marcin Kruszewski
    Academic press:
    BioFactors (rok: 2018, tom: 44, strony: 192-201), Wydawca: International Union of Biochemistry and Molecular Biology
    Status:
    Published
    DOI:
    10.1002/biof.1412 - link to the publication
  4. Biokompatybilny nośnik żelaza, sposób jego syntezy i zastosowanie medyczne
    Authors:
    Hanna Lewandowska, Grzegorz Wójciuk, Marcin Kruszewski
    Academic press:
    Biuletyn Urzędu Patentowego (rok: 2016, tom: b/d, strony: No. P.418581), Wydawca: Urząd Patentowy RP
    Status:
    Accepted for publication