Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Interactions of the nervous and the immune systems in compensatory mechanisms at the molecular and cellular levels

2012/07/B/NZ4/00205

Keywords:

Cyclooxygenases COX-1 COX-2 COX-4 nerw błędny wagotomia podprzeponowa Indomethacin

Descriptors:

  • NZ4_7: Neurophysiology
  • NZ4_8: Neuroendocrinology

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Marek Wieczorek 

Number of co-investigators in the project: 12

Call: OPUS 4 - announced on 2012-09-15

Amount awarded: 629 200 PLN

Project start date (Y-m-d): 2013-06-14

Project end date (Y-m-d): 2018-06-13

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Nie planowano.
  2. Autosampler HPLC-AGILENT (23 120 PLN)

Information in the final report

  • Publication in academic press/journals (1)
  • Articles in post-conference publications (10)
  1. Peripheral and central compensatory mechanisms for impaired vagus nerve function during peripheral immune activation
    Authors:
    Kobrzycka A, Napora P, Pearson BL, Pierzchała-Koziec K, Szewczyk R, Wieczorek M
    Academic press:
    Journal of Neuroinflammation (rok: 2019, tom: 16, strony: 45309), Wydawca: BMC Part of Springer Nature
    Status:
    Published
    DOI:
    10.1186/s12974-019-1544-y - link to the publication
  1. COX inhibitors influence on opioid and immune relationships after treatment LPS in rats
    Authors:
    Paweł Napora, Anna Kobrzycka, Krystyna Pierzchała-Koziec, Marek Wieczorek
    Conference:
    The XXVI International Symposium Molecular and Physiological Aspects of Regulatory Processes of the Organism (rok: 2017, ), Wydawca: Edited by Prof. dr hab. Henryk Lach
    Data:
    konferencja 16,09
    Status:
    Published
  2. Influence of subdiaphragmatic vagotomy on opioids and dopaminergic system activity in rats striatum
    Authors:
    Kobrzycka A., Napora P., Pierzchała-KoziecK., Wieczorek M.
    Conference:
    XXVII International Congress of the Polish Physiological Society, Białystok (rok: 2017, ), Wydawca: PTF
    Data:
    konferencja 21 –23.09
    Status:
    Published
  3. The influence of celecoxib on rat's behavior and its dopaminergic system activity in hypothalamus and amygdala after intraperitoneal injection of lipopolysaccharide
    Authors:
    Kacper Wróbel, Paweł Napora, Anna Kobrzycka, Marek Wieczorek
    Conference:
    MIKROBIOT 2017 (rok: 2017, ), Wydawca: Polskie Towarzystwo Mikrobiologów
    Data:
    konferencja 19-21.09
    Status:
    Published
  4. Inhibitory cyklooksygenaz i wagotomia modulują aktywność osi przysadkowo-nadnerczowej u szczurów
    Authors:
    Wieczorek M., Kobrzycka A., Pierzchała-Koziec K.
    Conference:
    XXI Zjazd Polskiego Towarzystwa Endokrynologicznego, Katowice (rok: 2016, ), Wydawca: PTE
    Data:
    konferencja 15 – 17.09
    Status:
    Published
  5. Subdiaphragmatic vagotomy does not protect against the increase of cerebral noradrenergic response in rat
    Authors:
    M. Wieczorek, A. Kobrzycka, A.H. Swiergiel, E. Oclon, J. Zubel, M. Hübner, M. Siudak
    Conference:
    Society for Neuroscience (rok: 2015, ), Wydawca: Society for Neuroscience
    Data:
    konferencja 17 - 21 październik
    Status:
    Published
  6. Subdiaphragmatic vagotomy does not protect against the increase of noradrenergic responseof the rat
    Authors:
    Wieczorek M., Kobrzycka A., Swiergiel A.H., Oclon E., Zubel J., Hübner M.,
    Conference:
    . 12th International Congress of the Polish Neuroscience Society, Gdańsk (rok: 2015, ), Wydawca: PTBUN
    Data:
    konferencja 6 – 8.09
    Status:
    Published
  7. Wpływ inhibitorów cyklooksygenaz i wagotomii na aktywność opioidów w prążkowiu szczurów
    Authors:
    Pierzchała-Koziec K., Wieczorek M., Kobrzycka A., Cieśla A
    Conference:
    . XXI Zjazd Polskiego Towarzystwa Endokrynologicznego, Katowice (rok: 2016, ), Wydawca: PTE
    Data:
    konferencja 15 – 17.09
    Status:
    Published
  8. Possible neural compensatory mechanisms for the communication between the nervous and immune systems after cyclooxygenase inhibition
    Authors:
    Kobrzycka A., Wieczorek M., Zubel J., Oclon E, Hübner M.
    Conference:
    12th International Congress of the Polish Neuroscience Society (rok: 2015, ), Wydawca: PTBUN
    Data:
    konferencja 6 – 8.09
    Status:
    Published
  9. Subdiaphragmatic vagotomy does not influenced rats behavior in elevated plus maze and does not protect against noradrenergic responses after i.p. LPS injection
    Authors:
    Wieczorek M., Kobrzycka A., Pierzchała-Koziec K., Swiergiel A.H., Siudak M
    Conference:
    IBNS 25th Annual Meeting, Budapest (rok: 2016, ), Wydawca: IBNS
    Data:
    konferencja 7-12.06
    Status:
    Published
  10. Interaction of opioid and immune systems in response to vagotomy and inflammation in rat
    Authors:
    Krystyna Pierzchała-Koziec, Marek Wieczorek, Anna Kobrzycka, Paweł Napora
    Conference:
    The XXVI International Symposium Molecular and Physiological Aspects of Regulatory Processes of the Organism (rok: 2017, ), Wydawca: Edited by Prof. dr hab. Henryk Lach
    Data:
    konferencja 16,09
    Status:
    Published