Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Epigenetic mechanisms controlling expression of genes involved in fat tissue accumulation in pigs

2012/07/E/NZ9/02573

Keywords:

epigenetics gene expression fat tissue accumulation adipogenesis chromatin modification three-dimensional nuclear organization

Descriptors:

  • NZ9_2: Animal production

Panel:

NZ9 - Fundamentals of applied life sciences and biotechnology: agricultural, forestry, horticulture, animal production and fishery, food and nutrition sciences, industrial biosciences, environmental biotechnology and remediation

Host institution :

Uniwersytet Przyrodniczy w Poznaniu, Wydział Medycyny Weterynaryjnej i Nauk o Zwierzętach

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Izabela Szczerbal 

Number of co-investigators in the project: 6

Call: SONATA BIS 2 - announced on 2012-09-15

Amount awarded: 1 492 340 PLN

Project start date (Y-m-d): 2013-07-08

Project end date (Y-m-d): 2018-12-07

Project duration:: 65 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Komora laminarna (45 000 PLN)
  2. Mikroskop fluorescencyjny wraz z oprogramowaniem (300 000 PLN)
  3. Termoblok - TProfessional Standard Gradient.
  4. Inkubator CO2 (40 000 PLN)

Information in the final report

  • Publication in academic press/journals (8)
  • Articles in post-conference publications (9)
  1. Expression of genes involved in lipid droplet formation (BSCL2, SNAP23 and COPA) during porcine in vitro adipogenesis
    Authors:
    Beata Kociucka, Tatiana Flisikowska, Dariusz Mróz, Izabela Szczerbal
    Academic press:
    Journal of Applied Genetics (rok: 2016, tom: 57, strony: 505-510), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s13353-016-0350-9 - link to the publication
  2. The importance of the nuclear positioning of the PPARG gene for its expression during porcine in vitro adipogenesis
    Authors:
    Joanna Stachecka, Joanna Nowacka-Woszuk, Pawel A. Kolodziejski, Izabela Szczerbal
    Academic press:
    Chromosome Research (rok: 2019, tom: 27, strony: 271-284), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s10577-019-09604-2 - link to the publication
  3. Investigation of allele-specific expression of genes involved in adipogenesis and lipid metabolism suggests complex regulatory mechanisms of PPARGC1A expression in porcine fat tissues
    Authors:
    Monika Stachowiak, Izabela Szczerbal, Krzysztof Flisikowski
    Academic press:
    BMC Genetics (rok: 2018, tom: 19, strony: 107), Wydawca: BMC
    Status:
    Published
    DOI:
    10.1186/s12863-018-0696-6 - link to the publication
  4. Expression of key genes involved in DNA methylation during in vitro differentiation of porcine mesenchymal stem cells (MSCs) into adipocytes
    Authors:
    Joanna Stachecka, Weronika Lemanska, Magdalena Noak, Izabela Szczerbal
    Academic press:
    Biochemical and Biophysical Research Communications (rok: 2019, tom: x, strony: x), Wydawca: Elsevier
    Status:
    Accepted for publication
    DOI:
    10.1016/j.bbrc.2019.11.175. - link to the publication
  5. Rapid Communication: The correlation between histone modifications and expression of key genes involved in accumulation of adipose tissue in the pig
    Authors:
    Beata Kociucka, Joanna Stachecka, Maciej Szydlowski, Izabela Szczerbal
    Academic press:
    Journal of Animal Science (rok: 2017, tom: 95, strony: 4514-4519), Wydawca: Oxford Academic
    Status:
    Published
    DOI:
    10.2527/jas2017.2010 - link to the publication
  6. Analysis of allele-specific expression of seven candidate genes involved in lipid metabolism in pig skeletal muscle and fat tissues reveals allelic imbalance of ACACA, LEP, SCD and TNF
    Authors:
    Monika Stachowiak, Krzysztof Flisikowski
    Academic press:
    Journal of Applied Genetics (rok: 2019, tom: 60, strony: 97-101), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s13353-019-00485-z - link to the publication
  7. Genetics of adiposity in large animal models – studied on pigs and dogs
    Authors:
    Monika Stachowiak, Izabela Szczerbal, Marek Switonski
    Academic press:
    Progress in Molecular Biology and Translational Science (rok: 2016, tom: 140, strony: 233-270), Wydawca: Elsevier Inc.
    Status:
    Published
    DOI:
    10.1016/bs.pmbts.2016.01.001 - link to the publication
  8. Nuclear organization during in vitro differentiation of porcine mesenchymal stem cells (MSCs) into adipocytes
    Authors:
    Joanna Stachecka, Agnieszka Walczak, Beata Kociucka, Błażej Ruszczycki, Grzegorz Wilczyński, Izabela Szczerbal
    Academic press:
    Histochemistry and Cell Biology (rok: 2018, tom: 149, strony: 113-126), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00418-017-1618-9 - link to the publication
  1. Histone modifications at promoter regions of key genes involved accumulation of adipose tissue in the pig
    Authors:
    Beata Kociucka, Joanna Stachecka, Maciej Szydłowsk, Izabela Szczerbal
    Conference:
    V Polski Kongres Genetyki, Łódź (rok: 2016, ), Wydawca: Materiały konferencyjne Polskigo Kongresu Genetyki
    Data:
    konferencja 19-22.09.2016
    Status:
    Published
  2. Nuclear organization during porcine in vitro adipogenesis
    Authors:
    Joanna Stachecka, Beata Kociucka, Izabela Szczerbal
    Conference:
    V Polski Kongres Genetyki, Łódź (rok: 2016, ), Wydawca: Materiały konferencyjne Polskigo Kongresu Genetyki
    Data:
    konferencja 19-22.09.2016
    Status:
    Published
  3. The role of nuclear architecture in regulating PPARG gene expression during porcine adipogenesis
    Authors:
    Joanna Stachecka, Joanna Nowacka-Woszuk, Paweł A. Kolodziejski, Izabela Szczerbal
    Conference:
    23rd International Colloquium on Animal Cytogenetics and Genomics (23 ICACG) (rok: 2018, ), Wydawca: Pensoft
    Data:
    konferencja 9-12.06.2018
    Status:
    Published
  4. Nuclear organization during in vitro differentiation of porcine mesenchymal stem cells (MSCs) into adipocytes
    Authors:
    Joanna Stachecka, Beata Kociucka, Izabela Szczerbal
    Conference:
    22nd International Colloquium on Animal Cytogenetic and Genomics, Toulouse, France (rok: 2016, ), Wydawca: Springer
    Data:
    konferencja July 2-5, 2016
    Status:
    Published
  5. Changes in expression of key genes involved in DNA methylation during in vitro differentiation of porcine mesenchymal stem cells (MSCs) into adipocytes
    Authors:
    Joanna Stachecka, Weronika Lemanska, Izabela Szczerbal
    Conference:
    International Conference Animal Genetics and Genomics (rok: 2018, ), Wydawca: Materiały konferencyjne
    Data:
    konferencja 02-04.07.2018
    Status:
    Published
  6. Exploring allele-specific expression of the pig PPARGC1A gene in subcutaneous fat, visceral fat and skeletal muscle
    Authors:
    Monika Stachowiak, Izabela Szczerbal, Krzysztof Flisikowski
    Conference:
    International Conference Animal Genetics and Genomics (rok: 2018, ), Wydawca: Materiały konferencyjne
    Data:
    konferencja 02-04.07.2018
    Status:
    Published
  7. Allele-specific expression of genes involved in adipogenesis and lipid metabolism in the pig
    Authors:
    Monika Stachowiak, Izabela Szczerbal, Krzysztof Flisikowski
    Conference:
    V Polski Kongres Genetyki, Łódź (rok: 2016, ), Wydawca: Materiały konferencyjne Polskigo Kongresu Genetyki
    Data:
    konferencja 19-22.09.2016
    Status:
    Published
  8. Three-dimensional (3D) nuclear positioning and expression of PPARG gene during porcine in vitro adipogenesis,
    Authors:
    Joanna Stachecka, Joanna Nowacka-Woszuk, Paweł A. Kolodziejski, Izabela Szczerbal
    Conference:
    International Conference Animal Genetics and Genomics (rok: 2018, ), Wydawca: Materiały konferencyjne
    Data:
    konferencja 02-04.07.2018
    Status:
    Published
  9. Expression of key genes involved in DNA methylation during in vitro differentiation of porcine mesenchymal stem cells (MSCs) into adipocytes
    Authors:
    Joanna Stachecka, Weronika Lemanska, Izabela Szczerbal
    Conference:
    23rd International Colloquium on Animal Cytogenetics and Genomics (23 ICACG) (rok: 2018, ), Wydawca: Pensoft
    Data:
    konferencja 9-12.06.2018
    Status:
    Published

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