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Information on the principal investigator and host institution

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The role of the re-initiation of cell cycle in postmitotic cells in response to oxidative stress and its role in AMD pathogenesis

2012/07/N/NZ3/01755

Keywords:

AMD apoptosis ARPE-19 DNA repair oxidative stress postmitotic cells re-initiation of cell cycle RPE,

Descriptors:

  • NZ3_1: Cell biology
  • NZ3_3: Apoptosis

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Paulina Tokarz zd. Gomulak 

Number of co-investigators in the project: 2

Call: PRELUDIUM 4 - announced on 2012-09-15

Amount awarded: 117 000 PLN

Project start date (Y-m-d): 2013-09-09

Project end date (Y-m-d): 2016-12-08

Project duration:: 39 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (4)
  1. All-Trans Retinoic Acid Modulates DNA Damage Response and the Expression of the VEGF-A and MKI67 Genes in ARPE-19 Cells Subjected to Oxidative Stress
    Authors:
    Tokarz P, Piastowska-Ciesielska AW, Kaarniranta K, Blasiak J
    Academic press:
    International Journal of Molecular Sciences (rok: 2016, tom: 17, strony: E898), Wydawca: MDPI Open Access Journals Platform
    Status:
    Published
    DOI:
    10.3390/ijms17060898 - link to the publication
  2. Role of the cell cycle re-initiation in DNA damage response of postmitotic cells and its implication in the pathogenesis of neurodegenerative diseases.
    Authors:
    Tokarz P, Blasiak J, Kaarniranta K
    Academic press:
    Rejuvenation Research (rok: 2016, tom: 19, strony: 131-9), Wydawca: MARY ANN LIEBERT, INC
    Status:
    Published
    DOI:
    10.1089/rej.2015.1717 - link to the publication
  3. Attenuation of DNA damage response by G0-like or G1 arrest and its restoration by cell cycle re-initiation
    Authors:
    Paulina Tokarz, Magdalena Kluska, Agnieszka W. Piastowska-Ciesielska, Janusz Błasiak, Maciej Jablkowski
    Academic press:
    Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis , Wydawca: Elsevier
    Status:
    Submitted
    DOI:
    brak - link to the publication
  4. All-trans retinoic acid decreases oxidative stress-induced death of acute promyelocytic leukemia cells through modulation of DNA damage response
    Authors:
    Paulina Tokarz, Katarzyna Wisniewska, Adam Staszewski, Agnieszka Piastowska-Ciesielska, Janusz Blasiak
    Academic press:
    Leukemia Research , Wydawca: Elsevier
    Status:
    Submitted
    DOI:
    brak - link to the publication

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