Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

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Polyprenol reductase - a new player in regulation of the dolichol cycle in eukaryotic cells

2012/06/M/NZ3/00155

Keywords:

polyprenol reductase dolichol cycle SRD5A3 Congenital Disorders of Glycosylation CDG

Descriptors:

  • NZ3_1: Cell biology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Instytut Biochemii i Biofizyki PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Ewa Kula-Świeżewska 

Number of co-investigators in the project: 13

Call: HARMONIA 3 - announced on 2012-06-15

Amount awarded: 950 000 PLN

Project start date (Y-m-d): 2013-05-07

Project end date (Y-m-d): 2016-09-06

Project duration:: 40 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (1)
  1. PolyPrenol ReDuctase 2 deficiency is lethal in Arabidopsis due to male sterility
    Authors:
    Jozwiak A, Gutkowska M, Gawarecka K, Surmacz L, Buczkowska A, Lichocka M, Nowakowska J, Swiezewska E.
    Academic press:
    Plant Cell (rok: 2015, tom: 27, strony: 3336-3353), Wydawca: AMER SOC PLANT BIOLOGISTS
    Status:
    Published
    DOI:
    10.1105/tpc.15.00463 - link to the publication
  2. Modeling of dolichol mass spectra isotopic envelopes as a tool to monitor isoprenoid biosynthesis
    Authors:
    Adam Jozwiak, Agata Lipko, Magdalena Kania, Witold Danikiewicz, Liliana Surmacz, Agnieszka Witek, Jacek Wojcik, Konrad Zdanowski, Cezary Pączkowski, Tadeusz Chojnacki, Jaroslaw Poznanski, Ewa Swiezewska
    Academic press:
    Plant Physiology (rok: 2017, tom: 174, strony: 857 - 874), Wydawca: AMER SOC PLANT BIOLOGISTS
    Status:
    Published
    DOI:
    10.1104/pp.17.00036 - link to the publication
  3. Combining QTL mapping and GWAS approach to dissect the polyisoprenoid accumulation in Arabidopsis
    Authors:
    K. Gawarecka, A. Siwinska, J. Poznanski, M. Kornneef, E. Swiezewska, A. Ihnatowicz
    Academic press:
    PLANT CELL AND ENVIRONMENT , Wydawca: WILEY-BLACKWELL
    Status:
    Submitted
  4. Genetic defects in dolichol metabolism
    Authors:
    Buczkowska A, Swiezewska E, Lefeber DJ
    Academic press:
    J Inherited Metabolic Disease (rok: 2015, tom: 38, strony: 157-169), Wydawca: SPRINGER
    Status:
    Published
    DOI:
    10.1007/s10545-014-9760-1 - link to the publication
  1. Cellular model of polyprenol reductase deficiency: useful tool for SRD5A3-CDG study.
    Authors:
    BUCZKOWSKA A.M., DZIEMBOWSKI A., LEFEBER D.J., SWIEZEWSKA E.
    Conference:
    European Human Genetics Conference, Milan, Italy, 31 May - 3 June 2014 (rok: 2014, ), Wydawca: Nature Publishing Group
    Data:
    konferencja 31 May - 3 June 2014
    Status:
    Published