Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

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Molecular mechanism of Ultraviolet radiation in initiation of skin photocancerogenesis.

2012/05/B/NZ5/01885

Keywords:

ultraviolet radiation skin basal cell carcinoma skin photodamage extracellular matrix

Descriptors:

  • NZ5_3: Pathogenesis of human diseases
  • NZ5_1: Etiology of human diseases
  • NZ5_9: Other related subjects

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Uniwersytet Medyczny w Łodzi, Wydział Lekarski z Oddziałem Stomatologicznym

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Aleksandra Lesiak 

Number of co-investigators in the project: 6

Call: OPUS 3 - announced on 2012-03-15

Amount awarded: 240 500 PLN

Project start date (Y-m-d): 2013-01-25

Project end date (Y-m-d): 2017-01-24

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (12)
  1. Molekularne aspekty fotostarzenia. Przegląd piśmiennictwa
    Authors:
    Michał Rogowski-Tylman, Joanna Narbutt, Anna Woźniacka, Aleksandra Lesiak
    Academic press:
    Przegląd Dermatologiczny (rok: 2016, tom: 103, strony: 139–142), Wydawca: Termedia
    Status:
    Published
    DOI:
    10.5114/dr.2016.59136 - link to the publication
  2. One week's holiday sun exposure induces expression of photoaging biomarkers
    Authors:
    Aleksandra Lesiak, Michał Rogowski-Tylman, Marian Danielewicz, Anna Woźniacka,Joanna Narbutt
    Academic press:
    Folia Histochemica et Cytobiologica (rok: 2016, tom: 1, strony: 45309), Wydawca: Via medica journals
    Status:
    Published
  3. Role of MMP-8 in photoaging and photocarcinogenesis
    Authors:
    Magdalena Ciążyńska1 , Joanna Narbutt2 , Anna Woźniacka2 , Aleksandra Lesiak2
    Academic press:
    Forum Drematologicum (rok: 2017, tom: 3, strony: 45358), Wydawca: Via Medica
    Status:
    Published
  4. One week of exposure to sunlight induces progerin expression in human skin
    Authors:
    Aleksandra Lesiak, Igor Aleksander Bednarski Michał Rogowski–Tylman, Michał Sobjanek, Anna Wozniacka, Marian Danielewicz, Antony R Young , Joanna Narbutt
    Academic press:
    Advances in Dermatology and Alergology (rok: 2017, tom: 6, strony: 629–631), Wydawca: Termedia
    Status:
    Published
    DOI:
    10.5114/pdia.2016.62416 - link to the publication
  5. Pigment Protection Factor as a Predictor of Skin Photosensitivity – A Polish Study
    Authors:
    Michal Rogowski Tylman, Joanna Narbutt, Malgorzata Fracczak, Anna Sysa- Jedrzejowska, Aleksandra Lesiak
    Academic press:
    Acta Dermatovenerologica Croat (rok: 2015, tom: 23, strony: 23-27), Wydawca: Portal of Scientific Journals of Croatia
    Status:
    Published
  6. Relation between sonic hedgehog pathway gene polymorphisms and basal cell carcinoma development in the Polish population.
    Authors:
    Lesiak A1, Sobolewska-Sztychny D2, Majak P3, Sobjanek M4, Wodz K5, Sygut KP6, Majsterek I6, Wozniacka A2, Narbutt J2.
    Academic press:
    Archives of Dermatological Research (rok: 2016, tom: 308, strony: 39-47), Wydawca: Springer Verlag
    Status:
    Published
    DOI:
    10.1007/s00403-015-1612-9. - link to the publication
  7. The alternative activation of hedgehog pathway induced by ultraviolet B radiation- preliminary study.
    Authors:
    Aleksandra Lesiak, Dorota Sobolewska‐Sztychny, Igor A. Bednarski, Karolina Wódz, Michał Sobjanek, Anna Woźniacka, Joanna Narbutt
    Academic press:
    Clinical and Experimental Dermatology (rok: 2018, tom: NA, strony: NA), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1111/ced.13394 - link to the publication
  8. Rola TGF-β w skórnej fotodestrukcji i kancerogenezie
    Authors:
    Magdalena Ciążyńska1 , Igor Bednarski1 , Aleksandra Lesiak2
    Academic press:
    Forum Dermatologicum (rok: 2016, tom: 2, strony: 60-63), Wydawca: Via Medica
    Status:
    Published
  9. UVR protection influences fructosamine level after sun exposure of healthy adults
    Authors:
    Mianowska B, Narbutt J, Young AR, Fendler W, Małachowska B, Młynarski W, Lesiak A.
    Academic press:
    Photodermatol Photoimmunol Photomed. (rok: 2016, tom: 32, strony: 296-303), Wydawca: Wiley online library
    Status:
    Published
    DOI:
    10.1111/phpp.12274. - link to the publication
  10. Trends in Basal Cell Carcinoma Incidence Rates: A 16-Year Retrospective Study of Population in Central Poland.
    Authors:
    Magdalena Ciążyńska, Joanna Narbutt, Anna Woźniacka, Aleksandra Lesiak
    Academic press:
    Advances of Dermatology and Alergology (rok: 2018, tom: 1, strony: 47-52), Wydawca: Termedia
    Status:
    Published
    DOI:
    10.5114/ada.2018.73164 - link to the publication
  11. Incidence rates of squamous cell carcinoma in Central Poland — a descriptive analysis of available data
    Authors:
    Magdalena Ciążyńska1 , Joanna Narbutt2 , Anna Woźniacka2 , Aleksandra Lesiak2
    Academic press:
    Forum Dermatologicum (rok: 2016, tom: 2, strony: 150-154), Wydawca: Via Medica
    Status:
    Published
  12. Związek polimorfizmów 331A/T w genie SHH oraz 385G/A w genie SMO z rozwojem raków podstawnokomórkowych skóry
    Authors:
    Dorota Sobolewska-Sztychny, Joanna Narbutt, Michał Sobjanek, Karolina Wódz, Joanna Sieniawska, Anna Woźniacka, Aleksandra Lesiak
    Academic press:
    Przegląd Dermatologiczny (rok: 2014, tom: 101, strony: 385-389), Wydawca: Termedia
    Status:
    Published
    DOI:
    10.5114/dr.2014.46068 - link to the publication