Yeast Metabolic Engineering for Construction of Advanced Producers of Ethanol

2012/05/B/NZ1/01657

Keywords

Descriptors

  • NZ1_1: Biologia molekularna
  • NZ1_5: Inżynieria genetyczna
  • NZ1_9: Biotechnologia

Panel

NZ1 – Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution

Uniwersytet Rzeszowski, Wydział Biologiczno-Rolniczy

Voivodeship: podkarpackie

Other projects carried out by the institution »

Principal investigator (from the host institution)

prof. Andriy Sybirnyy

Number of co-investigators in the project: 7

Call

OPUS 3 – announced on 2012-03-15

Amount awarded
350 000 PLN
Project start date
2013-02-26
Project end date
2016-02-25
Project duration
36 months (the same as in the proposal)
Project status
Project settled

Equipment purchased [PL]

  1. homogenizator. Cost: 9 000 PLN
  2. inkubator z wytrząsaniem. Cost: 51 000 PLN

Information in the final report

Publication in academic press/journals (8)

  1. Increased ethanol accumulation from glucose via reduction of ATP level in a recombinant strain of Saccharomyces cerevisiae overexpressing alkaline phosphatase

    Authors:
    Marta V Semkiv, Kostyantyn V Dmytruk, Charles A Abbas, Andriy A Sibirny
    Academic press:
    BMC Biotechnology (year: 2014, volume: 0,6125, pages: 46031), Publisher: BIOMED CENTRAL LTD, LONDON, ENGLAND
    Status:
    Published
    DOI:
    10.1186/1472-6750-14-42 – link to the publication
  2. New methods for positive selection of yeast ethanol overproducing mutants.

    Authors:
    Dmytruk KV, Kshanovska BV, Abbas CA, Sibirny AA
    Academic press:
    Bioethanol (year: 2015, volume: 2, pages: 24-31), Publisher: DeGruyter
    Status:
    Published
    DOI:
    10.1515/bioeth-2015-0003, – link to the publication
  3. Alcohol dehydrogenase gene ADH3 activates glucose alcoholic fermentation in genetically engineered Dekkerabruxellensis yeast.

    Authors:
    Schifferdecker AJ, Siurkus J, Andersen MR, Joerck-Ramberg D, Ling Z, Zhou N, Blevins JE, Sibirny AA, Piškur J, Ishchuk OP
    Academic press:
    Appl Microbiol Biotechnol. (year: 2016, volume: 1, pages: 46023), Publisher: Springer
    Status:
    Published
    DOI:
    10.1007/s00253-015-7266-x – link to the publication
  4. Development of a system for multicopy gene integration in Saccharomyces cerevisiae.

    Authors:
    Semkiv MV, Dmytruk KV, Sibirny AA.
    Academic press:
    J Microbiol Methods. (year: 2016, volume: 120, pages: 44-49), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.mimet.2015.10.023 – link to the publication
  5. Activation of the futile cycles as approach to increase ethanol yield during glucose fermentation in Saccharomyces cerevisiae.

    Authors:
    Semkiv MV, Dmytruk KV, Abbas CA, Sibirny AA.
    Academic press:
    Bioengineered (year: 2016, volume: 7(2), pages: 106-111), Publisher: Taylor and Francis
    Status:
    Published
    DOI:
    10.1080/21655979.2016.1148223 – link to the publication
  6. Overexpression of the genes PDC1 and ADH1 activates glycerol conversion to ethanol in the thermotolerant yeast Ogataea (Hansenula) polymorpha

    Authors:
    Kata I, Semkiv MV, Ruchala J, Dmytruk KV, Sibirny AA
    Academic press:
    Yeast (year: 2017, volume: 33, pages: 471-478), Publisher: Wiley Online Library
    Status:
    Published
    DOI:
    10.1002/yea.3175 – link to the publication
  7. New approaches for improving the production of the 1st and 2nd generation ethanol by yeast

    Authors:
    Kurylenko O, Semkiv M, Ruchala J, Hryniv O, Kshanovska B, Abbas C, Dmytruk K, Sibirny A.
    Academic press:
    Acta Biochimica Polonica (year: 2015, volume: 62, pages: 46030), Publisher: Polish Biochemical Society and of the Committee of Biochemistry and Biophysics Polish Academy of Sciences
    Status:
    Published
    DOI:
    10.18388/abp.2015_1156 – link to the publication
  8. Transcriptional activator Cat8 is involved in regulation of xylose alcoholic fermentation in the thermotolerant yeast Ogataea (Hansenula) polymorpha

    Authors:
    Ruchala J, Kurylenko OO, Soontorngun N, Dmytruk KV, Sibirny AA.
    Academic press:
    Microbiall Cell Factories (year: 2016, volume: 0,691666666666667, pages: 46035), Publisher: BioMed Central
    Status:
    Published
    DOI:
    10.1186/s12934-017-0652-6 – link to the publication

Book publications / chapters in book publications (1)

  1. New methods for selection of Saccharomyces cerevisiae ethanol overproducing mutants resistant to oxythiamine, trehalose, bromopyruvate, glyoxylic acid and glucosamine

    Authors:
    Dmytruk KV, Kshanovska B, Sibirny A
    Book:
    Living organisms and bioanalytical approaches for detoxification and monitoring of toxic compounds. Ed by A. Sibirny, D. Fedorovych, M. Gonchar, D. Grabek-Lejko (year: 2015, volume: 1, pages: 237-245), Publisher: University of Rzeszow
    Status:
    Published

« New search

Graphic design and implementation: Jakub Piotrowski