Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The specific substances in Kalanchoe daigremontiana roots and their biological activity

2012/05/B/NZ9/00812

Keywords:

Kalanchoe daigremontiana bufadienolides polyphenols blood platelets oxidative stress

Descriptors:

  • NZ9_7: Nutrition and food sciences

Panel:

NZ9 - Fundamentals of applied life sciences and biotechnology: agricultural, forestry, horticulture, animal production and fishery, food and nutrition sciences, industrial biosciences, environmental biotechnology and remediation

Host institution :

Instytut Uprawy Nawożenia i Gleboznawstwa - Państwowy Instytut Badawczy

woj. lubelskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Anna Stochmal 

Number of co-investigators in the project: 6

Call: OPUS 3 - announced on 2012-03-15

Amount awarded: 811 000 PLN

Project start date (Y-m-d): 2013-02-19

Project end date (Y-m-d): 2016-02-18

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Multivapor Buchi P-12 Professional, 230V/50Hz (90 000 PLN)
  2. Odgazowywacz próżniowy membranowy preparatywny (46 000 PLN)
  3. Zestaw komputerowy z oprogramowaniem Windows Proffesional oraz Office Proffesional (7 000 PLN)
  4. Termostat do kolumn 5-85 °C (Peltier) (14 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (5)
  • Book publications / chapters in book publications (1)
  1. Antioxidant efficacy of Kalanchoe daigremontiana bufadienolide-rich fraction in blood plasma in vitro
    Authors:
    Joanna Kołodziejczyk-Czepas, Paweł Nowak, Barbara Wachowicz, Justyna Stachniuk, Rafał Głowacki, Barbara Moniuszko-Szajwaj, Anna Stochmal
    Academic press:
    Pharmaceutical Biology (rok: 2016, tom: 54(12), strony: 3182-3188), Wydawca: Pharmaceutical Biology
    Status:
    Published
  2. Bufadienolides from Kalanchoe daigremontiana as thrombin inhibitors in vitro and in silico study.
    Authors:
    Kolodziejczyk-Czepas J., Sieradzka M., Moniuszko-Szajwaj B., Pecio Ł., Ponczek M.B., Nowak P., Stochmal A.
    Academic press:
    International Journal of Biological Macromolecules (rok: 2017, tom: 99, strony: 141-150), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ijbiomac.2017.02.051 - link to the publication
  3. New Bufadienolides Isolated from the Roots of Kalanchoe daigremontiana (Crassulaceae)
    Authors:
    Barbara Moniuszko-Szajwaj, Łukasz Pecio, Mariusz Kowalczyk, Anna Stochmal
    Academic press:
    Molecules (rok: 2016, tom: 21 (3), strony: 243-256), Wydawca: MDPI AG
    Status:
    Published
    DOI:
    10.3390/molecules21030243 - link to the publication