Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The role of insulin and insulin-like growth factor in clear cell renal cancer development and progression

2012/05/D/NZ5/01844

Keywords:

insulina insulinopodobny czynnika wzrostu raka nerki

Descriptors:

  • NZ3_7: Signal transduction
  • NZ1_1: Molecular biology
  • NZ5_1: Etiology of human diseases

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Wojskowy Instytut Medyczny

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Anna Czarnecka 

Number of co-investigators in the project: 5

Call: SONATA 3 - announced on 2012-03-15

Amount awarded: 495 250 PLN

Project start date (Y-m-d): 2013-03-18

Project end date (Y-m-d): 2016-03-17

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Aparat Luminex 200 lub równoważny (148 000 PLN)

Information in the final report

  • Publication in academic press/journals (8)
  • Articles in post-conference publications (5)
  • Book publications / chapters in book publications (2)
  1. The Role of Diabetes in Molecular Pathogenesis of Cancer
    Authors:
    Arthur Matyszewski, Anna M. Czarnecka, Piotr Korzen, Ilan J. Safir, Wojciech Kukwa and Cezary Szczylik.
    Academic press:
    Current Signal Transduction Therapy (rok: 2015, tom: 10(1), strony: 45581), Wydawca: BENTHAM SCIENCE PUBL LTD
    Status:
    Published
  2. Hormone signaling pathways as treatment targets in renal cell cancer
    Authors:
    Czarnecka AM, Niedzwiedzka M, Porta C, Szczylik C.
    Academic press:
    Int J Oncol. (rok: 2016, tom: 48(6), strony: 2221-35), Wydawca: Spandidos Publ. LTD
    Status:
    Published
    DOI:
    10.3892/ijo.2016.3460 - link to the publication
  3. Molecular basis of carcinogenesis in diabetic patients
    Authors:
    Matyszewski A, Czarnecka AM, Solarek W, Korzeń P, Safir IJ, Kukwa W, Szczylik C
    Academic press:
    Int J Oncol. (rok: 2015, tom: 46 (4), strony: 1435-1443), Wydawca: Spandidos Publ. LTD
    Status:
    Published
    DOI:
    10.3892/ijo.2015.2865 - link to the publication
  4. Impaired glucose metabolism treatment and carcinogenesis
    Authors:
    Matyszewski, Artur; Czarnecka, Anna; Kawecki, Maciej; et al.
    Academic press:
    Oncology Letters (rok: 2015, tom: 10(2), strony: 589-594), Wydawca: Spandidos Publ. LTD
    Status:
    Published
    DOI:
    10.3892/ol.2015.3324 - link to the publication
  5. The use of sunitinib in renal cell carcinoma: where are we now?
    Authors:
    Czarnecka AM, Szczylik C, Rini B
    Academic press:
    EXPERT REV ANTICANC (rok: 2014, tom: 14 (9), strony: 983-999), Wydawca: Informa Healthcare
    Status:
    Published
    DOI:
    10.1586/14737140.2014.941815 - link to the publication
  6. Insulin and IGFs in renal cancer risk and progression.
    Authors:
    Solarek W, Czarnecka AM, Escudier B, Bielecka ZF, Lian F, Szczylik C.
    Academic press:
    Endocr Relat Cancer (rok: 2015, tom: 22(5), strony: 253-64), Wydawca: Society for Endocrinology, BioScientifica
    Status:
    Published
    DOI:
    10.1530/ERC-15-0135 - link to the publication
  7. Mechanisms through which diabetes mellitus influences renal cell carcinoma development and treatment
    Authors:
    Labochka D, Moszczuk B, Kukwa W, Szczylik C, Czarnecka AM
    Academic press:
    International Journal of Molecular Medicine (rok: 2016, tom: 38(6), strony: 1887-1894), Wydawca: Spandidos Inc. LTD
    Status:
    Published
    DOI:
    10.3892/ijmm.2016.2776 - link to the publication
  8. Insulin and insulin-like growth factors act as renal cell cancer intratumoral regulators
    Authors:
    Solarek W, Koper M, Lewicki S, Szczylik C, Czarnecka AM
    Academic press:
    J Cell Commun Signal. (rok: 2019, tom: 45381, strony: [Epub ahead of print]), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s12079-019-00512-y - link to the publication
  1. Insulin signaling in renal cancer cells
    Authors:
    Solarek W, Koper M, Szczylik C, Czarnecka AM
    Conference:
    8th International Conference of Contemporary Oncology (rok: 2016, ), Wydawca: Termedia Publishing House- Contemporary Oncology
    Data:
    konferencja 16-18.03.2016
    Status:
    Published
  2. The influence of insulin and IGFs on renal cancer cells
    Authors:
    Solarek W, Szczylik C, Czarnecka AM
    Conference:
    Międzynarodowe Sympozjum "Rak nerki, rak prostaty 2015 - nowe wyzwania" (rok: 2015, ), Wydawca: Fundacja Onkologii Doświadczalnej i Klinicznej
    Data:
    konferencja 23-24.10.2015
    Status:
    Published
  3. The impact of insulin and insulin-like growth factor on renal cell carcinoma
    Authors:
    Solarek W, Lewicki A, Czarnecka AM, Szczylik C
    Conference:
    BIO 2014 Congress (rok: 2014, ), Wydawca: BIO 2014 Congress
    Data:
    konferencja 9-12.09.2014
    Status:
    Published
  4. Molecular events regulating clear cell renal cell cancer resistance to tyrosine kinase inhibitors
    Authors:
    Czarnecka AM, Bielecka ZF, Kamińska K, Matak D, Szymański Ł, Khan MI, Solarek W, Kornakiewicz A, Makiszewska-Olejniczak K, Szczylik C
    Conference:
    2015 ASCO Annual Meeting (rok: 2015, ), Wydawca: Journal of Clinical Oncology
    Data:
    konferencja 29.05-02.06.2015
    Status:
    Published
  5. Factors promoting survival and tyrosine kinase inhibitors resistance of clear cell renal cell carcinoma
    Authors:
    Czarnecka AM, Matak D, Solarek W, Khan MI, Kornakiewicz A, Szymański Ł, Szczylik C
    Conference:
    9th European International Kidney Cancer Symposium (rok: 2014, ), Wydawca: Kidney Cancer Association
    Data:
    konferencja 25-26.04.2014
    Status:
    Published
  1. Receptory i ich ścieżki sygnałowe jako targety dla kandydatów leków potęgujących działanie ewerolimusu w terapii raka nerki
    Authors:
    Kornakiewicz A, Czarnecka AM, Szczylik C
    Book:
    Dokonania Młodych Naukowców Nr 3 (rok: 2014, tom: 41671, strony: 19-24), Wydawca: CreativeTime
    Status:
    Published
  2. Terapia skojarzona jako obiecujące podejście w próbach przełamywania lekooporności w nowotworach
    Authors:
    Kornakiewicz A, Czarnecka AM, Szczylik CA
    Book:
    Wpływ młodych naukowców na osiągnięcia polskiej nauki (rok: 2014, tom: V, strony: 29-38), Wydawca: CreativeTime
    Status:
    Published