Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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The study of structure of miR21 RNA and its precursor - the basis marker of brain tumors in human.

2012/05/N/NZ1/01919

Keywords:

microRNA pre-miR21 miR21

Descriptors:

  • NZ1_2: Biochemistry
  • NZ1_1: Molecular biology
  • NZ3_1: Cell biology

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Instytut Chemii Bioorganicznej, Polska Akademia Nauk

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Agnieszka Belter 

Number of co-investigators in the project: 2

Call: PRELUDIUM 3 - announced on 2012-03-15

Amount awarded: 99 260 PLN

Project start date (Y-m-d): 2013-03-18

Project end date (Y-m-d): 2015-03-17

Project duration:: 24 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Zestaw komputerowy z oprogramowaniem (8 518 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (2)
  1. Inhibition of miR-21 in glioma cells using catalytic nucleic acids
    Authors:
    Belter A, Rolle K, Piwecka M, Fedoruk-Wyszomirska A, Naskręt-Barciszewska MZ, Barciszewski J
    Academic press:
    PLOS ONE (rok: 2016, tom: 6, strony: 45304), Wydawca: Nature Publishing Group
    Status:
    Published
    DOI:
    10.1038/srep24516 - link to the publication
  2. Mature miRNAs form secondary structure, which suggests their function beyond RISC
    Authors:
    Belter A, Gudanis D, Rolle K, Piwecka M, Gdaniec Z, Naskręt-Barciszewska MZ, Barciszewski J
    Academic press:
    PLOS ONE (rok: 2014, tom: 9, strony: e113848), Wydawca: Public Library of Science
    Status:
    Published
    DOI:
    10.1371/journal.pone.0113848 - link to the publication
  1. Anti-miRNA zymes as a potential tool for therapy of brain tumors
    Authors:
    Rolle K, Piwecka M, Belter A, Barciszewska AM, Barciszewska MZ, Barciszewski J
    Conference:
    40th FEBS Congress (rok: 2015, ), Wydawca: WILEY-BLACKWELL
    Data:
    konferencja 4-9.07.2015
    Status:
    Published
  2. Secondary structure of mature miRNAs suggests therapeutic approach
    Authors:
    -Belter A, Rolle K, Gudanis D, Piwecka M, Gdaniec Z, Naskręt-Barciszewska MZ, Barciszewski J
    Conference:
    40th FEBS Congress (rok: 2015, ), Wydawca: WILEY-BLACKWELL
    Data:
    konferencja 4-9.07.2015
    Status:
    Published

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