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Information on the principal investigator and host institution

Information of the project and the call

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Influence of individual genetic host factors, associated with DNA damage, antioxidant defence, metastasis and angiogenesis, and biochemical profile on treatment results in inoperable lung cancer

2012/05/B/NZ5/01905

Keywords:

polymorphism lung cancer radiotherapy DNA repair antioxidant defence metastasis angiogenesis

Descriptors:

  • NZ2_1: Molecular genetics
  • NZ4_12: Other related subjects

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Centrum Onkologii Instytut im. M Skłodowskiej–Curie Oddział w Gliwicach

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Dorota Butkiewicz 

Number of co-investigators in the project: 8

Call: OPUS 3 - announced on 2012-03-15

Amount awarded: 364 000 PLN

Project start date (Y-m-d): 2013-02-13

Project end date (Y-m-d): 2017-02-12

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (7)
  1. Truncating mutations of PPM1D are found in blood DNA samples of lung cancer patients.
    Authors:
    Zajkowicz A, Butkiewicz D, Drosik A, Giglok M, Suwiński R, Rusin M
    Academic press:
    British Journal of Cancer (rok: 2015, tom: 112(6), strony: 1114-20), Wydawca: Nature Publishing Group
    Status:
    Published
    DOI:
    10.1038/bjc.2015.79 - link to the publication
  2. Blood serum proteins as biomarkers for prediction of survival, locoregional control and distant metastases rate in radiotherapy and radiochemotherapy for non-small cell lung cancer
    Authors:
    Suwiński R, Giglok M, Galwas-Kliber K, Idasiak A, Jochymek B, Deja R, Masłyk B, Mrochem-Kwarciak J, Butkiewicz D
    Academic press:
    BMC Cancer , Wydawca: Springer Nature
    Status:
    Submitted
    DOI:
    brak - link to the publication
  3. The SIPA1-313A>G polymorphism is associated with prognosis in inoperable non-small cell lung cancer.
    Authors:
    Gdowicz-Kłosok A, Giglok M, Drosik A, Suwiński R, Butkiewicz D
    Academic press:
    Tumor Biology (rok: 2015, tom: 36(2), strony: 1273-78), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s13277-014-2753-8 - link to the publication
  4. The VEGFR2, COX-2 and MMP-2 polymorphisms are associated with clinical outcome of patients with inoperable non-small cell lung cancer.
    Authors:
    Butkiewicz D, Krześniak M, Drosik A, Giglok M, Gdowicz-Kłosok A, Kosarewicz A, Rusin M, Masłyk B, Gawkowska-Suwińska M, Suwiński R.
    Academic press:
    International Journal of Cancer (rok: 2015, tom: 137(10), strony: 2332-42), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/ijc.29605 - link to the publication
  1. Common DNA excision repair gene variants may influence the outcome in non-small cell lung cancer treated with definitive radiotherapy.
    Authors:
    D. Butkiewicz, M. Krześniak, M. Giglok, A. Drosik, B. Masłyk, I. Matuszczyk, M. Rusin, R. Suwiński
    Conference:
    9th International Conference of Anticancer Research, Sithonia, Grecja (rok: 2014, ), Wydawca: IIAR
    Data:
    konferencja 06-10.10.2014
    Status:
    Published
    DOI:
    link to the publication
  2. Relationship between polymorphisms in oxidative-stress related genes and therapy outcome in NSCLC
    Authors:
    D. Butkiewicz, M. Krześniak, M. Giglok, A. Drosik, A. Milewska, I. Matuszczyk, M. Rusin, R. Suwiński
    Conference:
    XVII Gliwice Scientific Meetings, Gliwice (rok: 2013, ), Wydawca: http://gsn.io.gliwice.pl/
    Data:
    konferencja 15-16.11.2013
    Status:
    Published
  3. Blood parameters as prognosticators in radiochemotherapy for non-small cell lung cancer.
    Authors:
    R. Suwiński, M.Giglok, K. Galwas-Kliber, U. Dworzecka, B. Jochymek, D. Butkiewicz, A. Tukiendorf, B. Masłyk
    Conference:
    3rd ESTRO Forum (rok: 2015, ), Wydawca: Elsevier Ireland Ltd.
    Data:
    konferencja 24-28.04.2015, Barcelona, Hiszpania
    Status:
    Published
    DOI:
    link to the publication
  4. The SIPA1 gene polymorphism as potential prognostic marker in non-small cell lung cancer – preliminary results.
    Authors:
    A. Gdowicz-Kłosok, A. Drosik, M. Giglok, M. Krześniak, I. Matuszczyk, R. Suwiński, D. Butkiewicz
    Conference:
    XVIII Gliwice Scientific Meetings (rok: 2014, ), Wydawca: http://gsn.io.gliwice.pl
    Data:
    konferencja 21-22.11.2014, Gliwice
    Status:
    Published
  5. Variation in DNA damage response and repair genes predicts survival in non-small cell lung cancer patients
    Authors:
    A. Gdowicz-Kłosok, M. Krześniak, M. Giglok, M. Marszałek-Zeńczak, I. Matuszczyk, R. Suwiński, D. Butkiewicz
    Conference:
    10th Anniversary International Conference of Contemporary Oncology (rok: 2018, ), Wydawca: Termedia Publishing House
    Data:
    konferencja 21-23.03.2018
    Status:
    Published
  6. Prognostic value of erythropoietin and hematological parameters in patients with non-small cell lung cancer
    Authors:
    J. Mrochem-Kwarciak, A. Chmura, R. Deja, B. Smolska-Ciszewska, T. Rutkowski, M. Giglok, D. Butkiewicz, R. Suwiński
    Conference:
    10th Anniversary International Conference of Contemporary Oncology (rok: 2018, ), Wydawca: Termedia Publishing House
    Data:
    konferencja 21-23.03.2018
    Status:
    Published
  7. Specific allele combinations in tumor progression genes are associated with lung cancer prognosis.
    Authors:
    M. Krześniak, A. Gdowicz-Kłosok, A. Drosik, M. Giglok, M. Rusin, B. Masłyk, M. Gawkowska-Suwińska, I. Matuszczyk, R. Suwiński, D. Butkiewicz
    Conference:
    XIX Gliwice Scientific Meetings (rok: 2015, ), Wydawca: http://gsn.io.gliwice.pl
    Data:
    konferencja 20-21.11.2015, Gliwice
    Status:
    Published

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