Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

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Comparison of cardioprotective effects of metformin and resveratrol on cardiomyocytes treated with epirubicin and trastuzumab.

2012/05/N/NZ7/01936

Keywords:

cardiomyocytes cardiac stem cells cardioprotection breast cancer epirubicin trastuzumab

Descriptors:

  • NZ7_12: Prevention of human diseases
  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology
  • NZ7_15: Toxicology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Fundacja Rozwoju Kardiochirurgii im. prof. Z Religi

woj. śląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Monika Bachorczyk 

Number of co-investigators in the project: 3

Call: PRELUDIUM 3 - announced on 2012-03-15

Amount awarded: 149 730 PLN

Project start date (Y-m-d): 2013-04-11

Project end date (Y-m-d): 2014-12-22

Project duration:: 20 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (1)
  • Articles in post-conference publications (2)
  1. Kardiotoksyczność jako niepożądane działanie uboczne w terapii raka piersi
    Authors:
    Michalina Gramatyka
    Academic press:
    Postępy Higieny i Medycyny Doświadczalnej (rok: 2014, tom: 68, strony: 483-498), Wydawca: Index Copernicus International
    Status:
    Published
    DOI:
    10.5604/17322693.1101581 - link to the publication
  1. Toxicity of epirubicin and trastuzumab to human cardiomyocytes and breast cancer cells in vitro
    Authors:
    Michalina Gramatyka
    Conference:
    XVIIth Gliwice Scientific Meetings (rok: 2013, ), Wydawca: --
    Data:
    konferencja 15-16 listopad
    Status:
    Published
  2. Metformin and resveratrol do not show cytoprotective activity in cardiomyocytes exposed to ionizng radiation and/or epirubicin.
    Authors:
    Michalina Gramatyka, Piotr Widłak
    Conference:
    XVIII Gliwickie Spotkania Naukowe (rok: 2014, ), Wydawca: --
    Data:
    konferencja 21-22.11
    Status:
    Published