Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Role of microRNA in the regulation of perivascular inflammation in hypertension and vascular dysfunction

2011/03/B/NZ4/02454

Keywords:

hypertension endothelial dysfunction angiotensin II oxidative stress

Descriptors:

  • NZ4_4: Pathophysiology

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Uniwersytet Jagielloński, Collegium Medicum, Wydział Lekarski

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Tomasz Guzik 

Number of co-investigators in the project: 4

Call: OPUS 2 - announced on 2011-09-15

Amount awarded: 598 900 PLN

Project start date (Y-m-d): 2012-09-04

Project end date (Y-m-d): 2016-03-03

Project duration:: 42 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Łażnia narządowa (140 000 PLN)

Information in the final report

  • Publication in academic press/journals (8)
  • Articles in post-conference publications (3)
  1. Macrophages come to mind as keys to cognitive decline.
    Authors:
    D.G. Harrison, Guzik TJ
    Academic press:
    Journal of Clinical Investigation (rok: 2016, tom: 126(12), strony: 4393–4395), Wydawca: ASCI
    Status:
    Published
    DOI:
    10.1172/JCI91277 - link to the publication
  2. Patofizjologia ludzkich naczyń krwionośnych a badania w modelach zwierzęcych – klucz do skutecznej translacji w chorobach sercowo naczyniowych.
    Authors:
    Urbanski K, Skiba D, Guzik TJ
    Academic press:
    Czynniki Ryzyka (rok: 2015, tom: 1/15 (78), strony: 28-34), Wydawca: PTBnM
    Status:
    Published
  3. BADANIA FUNKCJI ŚRÓDBŁONKA NACZYNIOWEGO A NOWE ALGORYTMY STRATYFIKACJI RYZYKA SERCOWO-NACZYNIOWEGO.
    Authors:
    Osmenda G., Wilk G., Nowak M., SLiwa T., Guzik TJ
    Academic press:
    Czynniki Ryzyka (rok: 2015, tom: 1/15(78), strony: 15-27), Wydawca: Polskie Towarzystwo Badań nad Miażdżycą/ Mededu sa
    Status:
    Published
  4. OCENA WPŁYWU HIPERPROLAKTYNEMII NA POZIOM BIAŁKA C-REAKTYWNEGO I STĘŻENIE LIPIDÓW W SUROWICY KRWI U KOBIET.
    Authors:
    Ignacak A., Kędzierska-Jamróz J, Śliwa T., Osmenda G., Jasiewicz-Honkisz B., Wilk G., Guzik T.
    Academic press:
    Czynniki Ryzyka (rok: 2015, tom: 1/15 (78), strony: 45518), Wydawca: Polskie Towarzystwo Badań nad Miażdżycą; Wyd:Mededu sp zo.o.
    Status:
    Published
  5. Novel Immune Mechanisms in Hypertension and Cardiovascular Risk.
    Authors:
    Nosalski R, McGinnigle E, Siedlinski M, Guzik TJ
    Academic press:
    Curr Cardiovasc Risk Rep. 2017;11(4):12. doi: 10.1007/s12170-017-0537-6 (rok: 2017, tom: 11(4):12, strony: 45650), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s12170-017-0537-6 - link to the publication
  6. Systemic T Cells and Monocyte Characteristics in Patients with Denture Stomatitis.
    Authors:
    Maciąg J, Mikołajczyk T, Matusik P, Nosalski R, Sagan A, Maciąg A, Nowakowski D, Wilk G, Osmenda G, Guzik T, Cześnikiewicz-Guzik M.
    Academic press:
    J Prosthodont. (rok: 2017, tom: 26(1), strony: 19-28), Wydawca: American Prosthodontics Society
    Status:
    Published
    DOI:
    10.1111/jopr.12447. - link to the publication
  7. Role of chemokine RANTES in the regulation of perivascular inflammation, T-cell accumulation, and vascular dysfunction in hypertension.
    Authors:
    Mikolajczyk TP, Nosalski R, Szczepaniak P, Budzyn K, Osmenda G, Skiba D, Sagan A, Wu J, Vinh A, Marvar PJ, Guzik B, Podolec J, Drummond G, Lob HE, Harrison DG, Guzik TJ.
    Academic press:
    FASEB J (rok: 2016, tom: 5, strony: in press), Wydawca: Federation of American Societies for Experimental Biology
    Status:
    Published
  8. The role of infiltrating immune cells in dysfunctional adipose tissue.
    Authors:
    Tomasz J. Guzik Dominik S. Skiba Rhian M. Touyz David G. Harrison
    Academic press:
    Cardiovascular Research (rok: 2017, tom: 113(9), strony: 1009–1023), Wydawca: Oxford University Press
    Status:
    Published
    DOI:
    10.1093/cvr/cvx108 - link to the publication
  1. Role of mir-214 in the regulation of perivascular fibrosis in angiotensin II-induced hypertension
    Authors:
    R.Nosalski, M.Siedlinski, A. Nguyen Dinh Cat, D.Skiba, E.Mcginnigle, A.Baker, L.Denby and T.J.Guzik
    Conference:
    American Heart Association Hypertension Scientific Sessions 2017; San Francisco (rok: 2017, ), Wydawca: American Heart Association
    Data:
    konferencja 14-17.09.2017
    Status:
    Published
  2. microRNA expression profile in aorta and perivascular adipose tissue in hypertension
    Authors:
    R. Nosalski, M. Siedlinski, M. Dulak-Lis, T. Mikolajczyk, A. Jozkowicz, T.J. Guzik
    Conference:
    European Atherosclerosis Society (rok: 2015, ), Wydawca: Elsevier
    Data:
    konferencja 22-25 Marzec 2015
    Status:
    Published
  3. CHRONIC ANGIOTENSIN II INFUSION CHANGES MICRORNA PROFILE IN MURINE AORTAS
    Authors:
    M. Dulak, M. Siedlinski, T. Mikolajczyk, R. Nosalski, R. Korbut, A. Jozkowicz, T.J. Guzik
    Conference:
    81st Congress of European Atherosclerosis Society (rok: 2013, ), Wydawca: Kenes International
    Data:
    konferencja 2-5.06.2013
    Status:
    Accepted for publication