Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Combined induction of cell death of canine leukemia and lymphoma.

2011/03/B/NZ5/01533

Keywords:

canine cell lines leukemia lymphoma apoptosis anticancer therapy

Descriptors:

  • NZ5_8: Animal disease treatment

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda PAN

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Andrzej Rapak 

Number of co-investigators in the project: 9

Call: OPUS 2 - announced on 2011-09-15

Amount awarded: 371 000 PLN

Project start date (Y-m-d): 2012-08-22

Project end date (Y-m-d): 2015-12-21

Project duration:: 40 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Zestaw pipet (3 500 PLN)
  2. Aparat do elektroforezy (5 000 PLN)
  3. Aparat do transferu (7 000 PLN)
  4. Komputer z oprogramowaniem (4 000 PLN)
  5. Wirówka z rotorami (40 000 PLN)
  6. Zasilacz do elektroforezy (4 000 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  1. A novel canine B-cell leukemia cell line. Establishment, characterization and sensitivity to chemotherapeutics.
    Authors:
    Aleksandra Pawlak, Ewa Ziolo, Justyna Kutkowska, Agnieszka Blazejczyk, Joanna Wietrzyk, Adriana Krupa, Wojciech Hildebrand, Stanisław Dzimira, Bożena Obmińska-Mrukowicz, Leon Strzadala, Andrzej Rapak
    Academic press:
    Veterinary and Comparative Oncology (rok: 2016, ), Wydawca: Wiley
    Status:
    Accepted for publication
    DOI:
    10.1111/vco.12257 - link to the publication
  2. Methotrexate induces high level of apoptosis in canine lymphoma/leukemia cell lines.
    Authors:
    Aleksandra Pawlak, Justyna Kutkowska, Bożena Obmińska-Mrukowicz, Andrzej Rapak
    Academic press:
    Res Vet Science (rok: 2017, tom: 114, strony: 518-523), Wydawca: ELSEVIER
    Status:
    Published
    DOI:
    10.1016/j.rvsc.2017.09.026 - link to the publication
  3. Pies jako model do badań porównawczych nad ludzkimi chłoniakami i białaczkami .
    Authors:
    Aleksandra Pawlak, Bożena Obmińska-Mrukowicz, Andrzej Rapak
    Academic press:
    Postepy Hig Med Dosw (rok: 2013, tom: 67, strony: 471-480), Wydawca: Instytut Immunologii i Terapii Doświadczalnej we Wrocławiu
    Status:
    Published
    DOI:
    10.5604/17322693.1050411 - link to the publication
  4. A novel established canine NK-type cell line and its cytotoxic properties.
    Authors:
    Andrzej Rapak, Aleksandra Pawlak, Ewa Ziolo, Justyna Kutkowska, Edyta Wysokińska, Magdalena Mielczarek, Joanna Wietrzyk, Wojciech Hildebrand, Bożena Obmińska-Mrukowicz, Leon Strzadala
    Academic press:
    BMC Vet Res , Wydawca: Springer
    Status:
    Submitted