Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Study of supramolecular interaction between the xenoandrogens and androgen receptor

2011/03/D/NZ7/02296

Keywords:

affinity chromatography drug-receptor affinity xenoandrogens

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology
  • NZ7_15: Toxicology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Mikołaja Kopernika, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy, Wydział Farmaceutyczny

woj. kujawsko-pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Michał Marszałł 

Number of co-investigators in the project: 4

Call: SONATA 2 - announced on 2011-09-15

Amount awarded: 686 660 PLN

Project start date (Y-m-d): 2012-09-18

Project end date (Y-m-d): 2015-09-17

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. System do pakowania kolumn chromatograficznych (23 000 PLN)
  2. zasilacz UPS.
  3. Precyzyjna waga analityczna.
  4. Detektor masowy ESI-MS (445 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  1. Lipase-immobilzed magnetic chitosan nanoparticles for kinetic resolution of (R.S)-ibuprofen
    Authors:
    T. Siódmiak, M. Ziegler-Borowska, M.P. Marszałł
    Academic press:
    Journal of Molecular Catalysis B: Enzymatic (rok: 2013, tom: 94, strony: 45487), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.molcatb.2013.04.008 - link to the publication
  2. Ligand fishing using new chitosan based functionalized Androgen Receptor magnetic particles
    Authors:
    M.P. Marszałł, W. D. Sroka, A. Sikora, D. Chełminiak, M. Ziegler-Borowska, T. Siódmiak, R. Moaddel
    Academic press:
    J. Pharmaceut. Biomed. Anal. (rok: 2016, tom: 127, strony: 129-135), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jpba.2016.04.013 - link to the publication
  3. Magnetic nanoparticles with surfaces modified with chitosan–poly[N-benzyl-2-(methacryloxy)-N,N-dimethylethanaminium bromide]for lipase immobilization
    Authors:
    Marta Ziegler-Borowska,Tomasz Siódmiak, Dorota Chełminiaka, Aleksandra Cyganiuk, Michał Piotr Marszałł
    Academic press:
    Applied Surface Science (rok: 2014, tom: 288, strony: 641-648), Wydawca: Elsevier
    Status:
    Published