Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The role of genetic variation in one-carbon metabolism cycle in the etiology of the metabolic syndrome in patients with schizophrenia

2011/03/N/NZ5/00248

Keywords:

the metabolic syndrome schizophrenia one-carbon metabolism polymorphism

Descriptors:

  • NZ5_1: Etiology of human diseases
  • NZ5_3: Pathogenesis of human diseases

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Lekarski Kształcenia Podyplomowego

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Błażej Misiak 

Number of co-investigators in the project: 3

Call: PRELUDIUM 2 - announced on 2011-09-15

Amount awarded: 282 400 PLN

Project start date (Y-m-d): 2012-08-06

Project end date (Y-m-d): 2015-08-05

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Oprogramowanie (antywirus, Microsoft Office).
  2. Zamrażarka (1 000 PLN)
  3. Komputer notebook (3 000 PLN)

Information in the final report

  • Publication in academic press/journals (12)
  • Articles in post-conference publications (3)
  1. Assessment of cigarette smoking status with respect to symptomatic manifestation in first-episode schizophrenia patients
    Authors:
    Błażej Misiak, Andrzej Kiejna, Dorota Frydecka
    Academic press:
    Comprehensive Psychiatry (rok: 2015, tom: 58, strony: 146-151), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.comppsych.2014.11.024 - link to the publication
  2. Elevated homocysteine level in first-episode schizophrenia patients--the relevance of family history of schizophrenia and lifetime diagnosis of cannabis abuse.
    Authors:
    Błażej Misiak, Dorota Frydecka, Patryk Piotrowski, Ryszard Ślęzak, Andrzej Kiejna
    Academic press:
    Metabolic Brain Disease (rok: 2014, tom: 29, strony: 661-670), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s11011-014-9534-3 - link to the publication
  3. The multidimensional nature of metabolic syndrome in schizophrenia: lessons from studies of one-carbon metabolism and DNA methylation.
    Authors:
    Błażej Misiak, Dorota Frydecka, Patryk Piotrowski, Andrzej Kiejna
    Academic press:
    Epigenomics (rok: 2013, tom: 5(3), strony: 317-329), Wydawca: Future Medicine
    Status:
    Published
    DOI:
    10.2217/epi.13.22 - link to the publication
  4. Effects of antipsychotics and psychopathological symptoms on insight in schizophrenia - results from independent samples of first-episode and acutely relapsed patients
    Authors:
    Błażej Misiak, Dorota Frydecka, Jan Aleksander Beszłej, Przemysław Tybura, Jolanta Kucharska-Mazur, Agnieszka Samochowiec, Przemysław Bieńkowski, Jerzy Samochowiec
    Academic press:
    International Clinical Psychopharmacology (rok: 2016, tom: 31, strony: 185-191), Wydawca: Lipincott, Williams & Wilkins
    Status:
    Published
    DOI:
    10.1097/YIC.0000000000000120 - link to the publication
  5. Higher total cholesterol level is associated with suicidal ideation in first-episode schizophrenia females
    Authors:
    Błażej Misiak, Andrzej Kiejna, Dorota Frydecka
    Academic press:
    Psychiatry Research (rok: 2015, tom: 226, strony: 383-388), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.psychres.2014.12.030 - link to the publication
  6. Metabolic dysregulation in first-episode schizophrenia patients with respect to genetic variation in one-carbon metabolism
    Authors:
    Błażej Misiak, Łukasz Łaczmański, Natalia Kinga Słoka, Elżbieta Szmida, Patryk Piotrowski, Olga Loska, Ryszard Ślęzak, Andrzej Kiejna, Dorota Frydecka
    Academic press:
    Psychiatry Research (rok: 2016, tom: 238, strony: 60-67), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.psychres.2016.01.077 - link to the publication
  7. A History of Childhood Trauma and Response to Treatment With Antipsychotics in First-Episode Schizophrenia Patients: Preliminary Results
    Authors:
    Błażej Misiak, Dorota Frydecka
    Academic press:
    Journal of Nervous and Mental Disease (rok: 2016, tom: 204, strony: 787-792), Wydawca: Wolters Kluver
    Status:
    Published
    DOI:
    10.1097/NMD.0000000000000567 - link to the publication
  8. Effects of second-generation antipsychotics on selected markers of one-carbon metabolism and metabolic syndrome components in first-episode schizophrenia patients
    Authors:
    Błażej Misiak, Dorota Frydecka, Łukasz Łaczmański, Ryszard Ślęzak, Andrzej Kiejna
    Academic press:
    European Journal of Clinical Pharmacology (rok: 2014, tom: 70, strony: 1433-1441), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00228-014-1762-2 - link to the publication
  9. Genetic Variation in One-Carbon Metabolism and Changes in Metabolic Parameters in First-Episode Schizophrenia Patients
    Authors:
    Błażej Misiak, Łukasz Łaczmański, Natalia Kinga Słoka, Elżbieta Szmida, Ryszard Ślęzak, Patryk Piotrowski, Andrzej Kiejna, Dorota Frydecka
    Academic press:
    International Journal of Neuropsychopharmacology (rok: 2017, tom: 20, strony: 207-212), Wydawca: Oxford Academic
    Status:
    Published
    DOI:
    10.1093/ijnp/pyw094 - link to the publication
  10. Homocysteine levels in schizophrenia and affective disorders-focus on cognition
    Authors:
    Ahmed A Moustafa, Doaa H Hewedi, Abeer M Eissa, Dorota Frydecka, Błażej Misiak
    Academic press:
    Frontiers in Behavioural Neuroscience (rok: 2014, tom: 8, strony: 343), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fnbeh.2014.00343 - link to the publication
  11. The history of childhood trauma is associated with lipid disturbances and blood pressure in adult first-episode schizophrenia patients.
    Authors:
    Błażej Misiak, Andrzej Kiejna, Dorota Frydecka
    Academic press:
    General Hospital Psychiatry (rok: 2015, tom: 37, strony: 365-367), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.genhosppsych.2015.03.017 - link to the publication
  12. Childhood traumatic events and types of auditory verbal hallucinations in first-episode schizophrenia patients
    Authors:
    Błażej Misiak, Ahmed A. Moustafa, Andrzej Kiejna, Dorota Frydecka
    Academic press:
    Comprehensive Psychiatry (rok: 2016, tom: 66, strony: 17-22), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.comppsych.2015.12.003 - link to the publication
  1. Baseline cardiometabolic risk in a cohort of first-episode schizophrenia patients
    Authors:
    Błażej Misiak, Patryk Piotrowski, Ryszard Ślęzak, Andrzej Kiejna, Dorota Frydecka
    Conference:
    28th European College of Neuropsychopharmacology (ECNP) Congress (rok: 2015, ), Wydawca: Elsevier (European Neuropsychopharmacology)
    Data:
    konferencja 29.08.2015 - 01.09.2015
    Status:
    Published
  2. Lifetime diagnosis of cannabis use disorders is associated with plasma levels of homocysteine and folic acid in first-episode schizophrenia patients
    Authors:
    Błażej Misiak, Dorota Frydecka, Ryszard Ślęzak, Patryk Piotrowski, Andrzej Kiejna
    Conference:
    XVI World Congress of Psychiatry "Focusing on access, quality and human care" (rok: 2014, ), Wydawca: World Psychiatric Association
    Data:
    konferencja 14-18 września 2014
    Status:
    Published
  3. Plasma homocysteine, folic acid and vitamin B12 in first-episode schizophrenia patients
    Authors:
    Błażej Misiak, Dorota Frydecka, Ryszard Ślęzak, Patryk Piotrowski, Andrzej Kiejna
    Conference:
    22nd European Congress of Psychiatry (rok: 2014, ), Wydawca: Elsevier
    Data:
    konferencja 1-3 marca 2014
    Status:
    Published
    DOI:
    link to the publication

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