Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Identification of epigenetic biomarkers of stress using mouse model

2011/03/N/NZ9/05222

Keywords:

epigenetics stress chronic social stress DNA methylation biomarkers of stress hippocampus leukocytes

Descriptors:

  • NZ2_2: Genomics, transcriptomics, epigenomics
  • NZ4_9: Systems neurobiology
  • NZ9_2: Animal production

Panel:

NZ9 - Fundamentals of applied life sciences and biotechnology: agricultural, forestry, horticulture, animal production and fishery, food and nutrition sciences, industrial biosciences, environmental biotechnology and remediation

Host institution :

INSTYTUT GENETYKI I HODOWLI ZWIERZĄT PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Adrian Stankiewicz 

Number of co-investigators in the project: 3

Call: PRELUDIUM 2 - announced on 2011-09-15

Amount awarded: 366 000 PLN

Project start date (Y-m-d): 2012-08-21

Project end date (Y-m-d): 2015-02-20

Project duration:: 30 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Sprzęt wideo do monitorowania zachowania zwierząt (do systemu Ethovision) 5000 (5 000 PLN)

Information in the final report

  • Publication in academic press/journals (5)
  • Articles in post-conference publications (2)
  1. Novel candidate genes for alcoholism – transcriptomic analysis of prefrontal medial cortex, hippocampus and nucleus accumbens of Warsaw alcohol-preferring and non-preferring rats
    Authors:
    Stankiewicz AM, Goscik J, Dyr W, Juszczak GR, Ryglewicz D, Swiergiel AH, Wieczorek M, Stefanski R
    Academic press:
    Pharmacology Biochemistry and Behavior (rok: 2015, tom: 139, strony: 27-38), Wydawca: Elsevier
    Status:
    Published
  2. Social stress increases expression of hemoglobin genes in mouse prefrontal cortex.
    Authors:
    Stankiewicz AM, Goscik J, Swiergiel AH, Majewska A, Wieczorek M, Juszczak GR, Lisowski P.
    Academic press:
    BMC Neuroscience (rok: 2014, tom: 15, strony: 130-146), Wydawca: BioMed Central
    Status:
    Published
    DOI:
    10.1186/s12868-014-0130-6 - link to the publication
  3. The effect of acute and chronic social stress on hippocampal transcriptome in mice
    Authors:
    Stankiewicz AM, Goscik J, Swiergiel AH, Juszczak GR
    Academic press:
    PLoS ONE (rok: 2015, tom: 10, strony: e0142195), Wydawca: Public Library of Science
    Status:
    Published
    DOI:
    10.1371/journal.pone.0142195 - link to the publication
  4. Epigenetics of stress adaptations in the brain.
    Authors:
    Stankiewicz AM, Swiergiel AH, Lisowski P.
    Academic press:
    Brain Research Bulletin (rok: 2013, tom: 98, strony: 76-92), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.brainresbull.2013.07.003 - link to the publication
  5. Pregnancy at Advanced Maternal Age Affects Behavior and Hippocampal Gene Expression in Mouse Offspring
    Authors:
    Sampino S, Stankiewicz AM, Zacchini F, Goscik J, Szostak A, Swiergiel AH, Drago G, Modlinski JA, Ptak GE
    Academic press:
    The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences (rok: 2017, tom: 22, strony: [Epub ahead of print]), Wydawca: Oxford Academic
    Status:
    Published
    DOI:
    10.1093/gerona/glx016 - link to the publication
  1. Limbic system transcriptome profiling in alcohol-preferring and nonpreferring rats
    Authors:
    Wieczorek M, Stankiewicz AM, Goscik J, Stefanski R, Dyr W, Ryglewicz D, Swiergiel AH, Lisowski P.
    Conference:
    Neuroscience 2013 (rok: 2013, ), Wydawca: Society for Neuroscience
    Data:
    konferencja 9-13 11 2013
    Status:
    Published
  2. Dynamics of gene expression patterns in frontal cortex and hippocampus of mice subjected to chronic social stress
    Authors:
    Stankiewicz AM, Swiergiel AH, Juszczak GR, Goscik J, Majewska A, Lisowski P
    Conference:
    Neuroscience 2013 (rok: 2013, ), Wydawca: Society for Neuroscience
    Data:
    konferencja 9-13 11 2013
    Status:
    Published