Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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New methods for synthesis of B-amino alcohols substituted with trifluoromethyl group with usage of glyoxals and their derivatives

2011/03/D/ST5/05231

Keywords:

(trifluoromethyl)trimethylsilane glyoxals B-amino alcohols amino-(trifluoromethyl) alcohols asymmetric synthesis

Descriptors:

  • ST5_23:
  • ST5_18:

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

UNIWERSYTET ŁÓDZKI, Wydział Chemii

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Emilia Obijalska 

Number of co-investigators in the project: 4

Call: SONATA 2 - announced on 2011-09-15

Amount awarded: 301 800 PLN

Project start date (Y-m-d): 2012-08-29

Project end date (Y-m-d): 2015-10-28

Project duration:: 38 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Chłodziarko-zamrażarka.
  2. Kolektor frakcji (12 000 PLN)
  3. Pompa membranowa (24 600 PLN)
  4. Zestaw: wyparka próżniowa + pompa membranowa (25 500 PLN)
  5. Chiralna kolumna HPLC (4 905 PLN)
  6. Zestaw mebli laboratoryjnych (3 997 PLN)
  7. Lampa UV.
  8. Laptop z oprogramowaniem (4 500 PLN)
  9. Mieszadło magnetyczne z termometrem kontaktowym (4 500 PLN)
  10. Waga analityczna (4 500 PLN)

Information in the final report

  • Publication in academic press/journals (5)
  1. Enantioselective additions of (trifluoromethyl)trimethylsilane to α-imino ketones derived from aryl glyoxals
    Authors:
    Emilia Obijalska, Grzegorz Mloston, Alice Six
    Academic press:
    Tetrahedron Letters (rok: 2013, tom: 54, strony: 2462-2465), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.tetlet.2013.02.093 - link to the publication
  2. Nucleophilic addition of (difluoromethyl)trimethylsilane to selected α-imino ketones and aryl diketones
    Authors:
    Emilia Obijalska, Greta Utecht, Marcin K. Kowalski, Grzegorz Mlostoń, Michał Rachwalski
    Academic press:
    Tetrahedron Letters (rok: 2015, tom: 56, strony: 4701-4703), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.tetlet.2015.06.025 - link to the publication
  3. Chemoselective trifluoromethylation of the C=N group of a-iminoketones derived from arylglyoxals
    Authors:
    E. Obijalska, M.K. Kowalski, G. Mlostoń, H. Heimgartner
    Academic press:
    Journal of Fluorine Chemistry (rok: 2014, tom: 168, strony: 151-157), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jfluchem.2014.09.002 - link to the publication
  4. Nucleophilic trifluoromethylation of aziridinyl ketones: A convenient access to fluorinated aziridinyl alcohols
    Authors:
    Grzegorz Mloston, Emilia Obijalska, Paulina Ziebacz, Krzysztof Matyszewski, Katarzyna Urbaniak, Anthony Linden, Heinz Heimgartner
    Academic press:
    Journal of Fluorine Chemistry (rok: 2013, tom: 156, strony: 192-197), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jfluchem.2013.09.011 - link to the publication
  5. A new approach to a-(trifluoromethyl)benzyl substituted oxaziridines
    Authors:
    Emilia Obijalska, Grzegorz Mloston, Greta Utecht, Heinz Heimgartner
    Academic press:
    Journal of Fluorine Chemistry (rok: 2013, tom: 151, strony: 45484), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jfluchem.2013.03.018 - link to the publication