Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Molecular aspects of the porcine corpus luteum functioning during pregnancy in experimentally restricted access of androgens - in vivo stydy.

2011/03/D/NZ4/00303

Keywords:

corpus luteum pregnancy flutamide pig

Descriptors:

  • NZ4_2: Physiology
  • NZ4_6: Endocrinology

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Uniwersytet Jagielloński, Wydział Biologii i Nauk o Ziemi

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Małgorzata Grzesiak 

Number of co-investigators in the project: 4

Call: SONATA 2 - announced on 2011-09-15

Amount awarded: 396 620 PLN

Project start date (Y-m-d): 2012-09-21

Project end date (Y-m-d): 2015-09-20

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Mikroskop biologiczny klasy badawczej z kontrastem Nomarskiego Nikon ECLIPSE NI-U (127 000 PLN)
  2. Rotator Multi RS-60 z platformą PRS-8/22.

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (3)
  1. Androgen deficiency during mid- and late pregnancy alters progesterone production and metabolism in the porcine corpus luteum.
    Authors:
    Małgorzata Grzesiak, Katarzyna Knapczyk-Stwora, Renata E. Ciereszko, Aniela Gołas, Iwona Wieciech, Maria Słomczyńska
    Academic press:
    Reproductive Sciences (rok: 2014, tom: 21(6), strony: 778-790), Wydawca: SAGE
    Status:
    Published
    DOI:
    10.1177/1933719113518991 - link to the publication
  2. Ciałko żółte - mały gruczoł o wilekim znaczeniu.
    Authors:
    Agata Mitan, Małgorzata Grzesiak
    Academic press:
    Kosmos (rok: 2015, tom: 64, strony: 247-259), Wydawca: Polskie Towarzystwo Przyrodników im. Kopernika, Wydawnictwo Naukowe Mikołaja Kopernika w Toruniu
    Status:
    Published
  3. Alterations in luteal production of androstenedione, testosterone, and estrone, but not estradiol, during midand late pregnancy in pigs: Effects of androgen deficiency
    Authors:
    Małgorzata Grzesiak, Katarzyna Knapczyk-Stwora, Renata E. Ciereszko, Iwona Wieciech, Maria Słomczyńska
    Academic press:
    Theriogenology (rok: 2014, tom: 82, strony: 720-733), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.theriogenology.2014.06.005 - link to the publication
  4. Flutamide alters β-catenin expression and distribution, and its interactions with E-cadherin in the porcine corpus luteum of mid- and late pregnancy.
    Authors:
    Małgorzata Grzesiak, Agata Mitan, Marcelina E. Janik, Katarzyna Knapczyk-Stwora, Maria Słomczyńska
    Academic press:
    Histology and Histopathology (rok: 2015, tom: 30, strony: 1341-1352), Wydawca: -
    Status:
    Published
    DOI:
    10.14670/HH-11-630 - link to the publication
  1. Flutamide-induced alterations in CYP17A1 gene expression and local testosterone synthesis in porcine luteal tissue – a new insight into androgens action during pregnancy
    Authors:
    Malgorzata Grzesiak, Katarzyna Knapczyk-Stwora, Iwona Wieciech, Renata E. Ciereszko, Maria Slomczynska
    Conference:
    15th European Congress of Endocrinology (rok: 2013, ), Wydawca: Bioscientifica
    Data:
    konferencja 27 kwietnia - 1 maja
    Status:
    Published
  2. Androgen deficiency affects luteal beta-catenin expression and its interactions with E-cadherin during pregnancy in pigs
    Authors:
    Małgorzata Grzesiak, Katarzyna Knapczyk-Stwora, Marcelina Janik, Małgorzata Grzesiak
    Conference:
    18th Annual Conference of the European Society for Domestic Animal Reproduction (ESDAR) (rok: 2014, ), Wydawca: Blackwell Verlag GmbH
    Data:
    konferencja 11-13 września
    Status:
    Published
  3. Flutamide administration during late pregnancy downregulates CYP11A and 3β-HSD genes expression in the porcine corpus luteum.
    Authors:
    Małgorzata Grzesiak, Katarzyna Knapczyk-Stwora, Maria Słomczyńska
    Conference:
    The 3rd Winter Workshop of the Society for Biology of Reproduction Central and Local Regulations of Reproductive Processes". (rok: 2013, ), Wydawca: Elsevier
    Data:
    konferencja 31 styczeń - 2 luty
    Status:
    Published