Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

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Novel functions of endocytic proteins in transcriptional regulation

2011/02/A/NZ3/00149

Keywords:

endocytosis transcription signal transduction

Descriptors:

  • NZ3_1: Cell biology
  • NZ3_7: Signal transduction

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej (MIBMiK)

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Marta Miączyńska 

Number of co-investigators in the project: 4

Call: MAESTRO 1 - announced on 2011-06-15

Amount awarded: 2 875 000 PLN

Project start date (Y-m-d): 2012-05-18

Project end date (Y-m-d): 2018-05-18

Project duration:: 72 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (5)
  1. Multiple routes of endocytic internalization of PDGFRβ contribute to PDGF-induced STAT3 signaling.
    Authors:
    Kamil Jastrzębski, Daria Zdżalik-Bielecka, Agnieszka Mamińska, Yannis Kalaidzidis, Carina Hellberg, Marta Miączyńska
    Academic press:
    Journal of Cell Science (rok: 2017, tom: 130, strony: 577-589), Wydawca: The Company of Biologists
    Status:
    Published
    DOI:
    10.1242/jcs.191213 - link to the publication
  2. The topology of lymphotoxin β receptor (LTβR) that accumulates upon endolysosomal dysfunction dictates the NF-κB signaling outcome
    Authors:
    Magdalena Banach-Orłowska, Kamil Jastrzębski, Jarosław Cendrowski, Małgorzata Maksymowicz, Karolina Wojciechowska, Michał Korostyński, Dimitri Moreau, Jean Gruenberg, Marta Miaczynska
    Academic press:
    Journal of Cell Science (rok: 2018, tom: 131, strony: jcs218883), Wydawca: The Company of Biologists
    Status:
    Published
    DOI:
    10.1242/jcs.218883 - link to the publication
  3. Impaired dynamin 2 function leads to increased AP-1 transcriptional activity through the JNK/c-Jun pathway.
    Authors:
    Ewelina Szymanska, Agnieszka Skowronek, Marta Miaczynska
    Academic press:
    Cellular Signalling (rok: 2016, tom: 28, strony: 160-71), Wydawca: Elsevier
    Status:
    Published
  4. Splicing variants of BMP2K, an erythroid-enriched endocytic kinase, coordinate SEC16A-dependent autophagy
    Authors:
    Jaroslaw Cendrowski, Marta Kaczmarek, Katarzyna Kuzmicz-Kowalska, Michal Mazur, Kamil Jastrzebski, Agata Kominek, Katarzyna Piwocka, Marta Miaczynska
    Academic press:
    eLife (rok: 2019, tom: -, strony: -), Wydawca: eLife Sciences Publications
    Status:
    Submitted
  5. Endocytic adaptor protein Tollip inhibits canonical Wnt signaling
    Authors:
    Anna Toruń, Ewelina Szymańska, Irinka Castanon, Lidia Wolińska-Nizioł, Anna Bartosik, Kamil Jastrzębski, Magdalena Miętkowska, Marcos González-Gaitán, Marta Miaczynska
    Academic press:
    PLOS ONE (rok: 2015, tom: e0130818, strony: 45318), Wydawca: Public Library of Science
    Status:
    Published
    DOI:
    10.1371/journal.pone.0130818 - link to the publication