Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Evaluation of the pertussis toxin level produced in vitro in respect to the alleles of promoter of gene encoding pertussis toxin ptxP as factor increasing the virulence of Bordetella pertussis strains potentially responsible for epidemic increase of pertussis cases in Poland

2011/01/N/NZ7/05305

Keywords:

pertussis Bordetella pertussis pertussis toxin

Descriptors:

  • NZ7_3: Physical culture and health promotion
  • NZ7_1: Epidemiology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Narodowy Instytut Zdrowia Publicznego - Państwowy Zakład Higieny (NIZP - PZH)

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Monika Zawadka 

Number of co-investigators in the project: 4

Call: PRELUDIUM 1 - announced on 2011-03-15

Amount awarded: 136 600 PLN

Project start date (Y-m-d): 2011-12-13

Project end date (Y-m-d): 2014-01-12

Project duration:: 25 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Wirówka z chłodzeniem z adapterem do wirowania probówek typu Eppendorf i próbówek typu falcon (30 000 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  1. Sequence variation in virulence-related genes of Bordetella pertussis isolates from Poland in the period 1959-2013
    Authors:
    Mosiej E., Zawadka M., Krysztopa-Grzybowska K., Polak M., Augustynowicz E., Piekarska K., Lutyńska A
    Academic press:
    Eur J Clin Microbiol Infect Dis (rok: 2015, tom: 34, strony: 147-152), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s10096-014-2216-6 - link to the publication
  2. Ocena toksyczności szczepów Bordetella pertussis z zastosowaniem linii komórkowych CHO in vitro
    Authors:
    Zawadka M., Rabczenko D., Lutyńska A.
    Academic press:
    Medycyna Doświadczalna i Mikrobiologia (rok: 2014, tom: 66, strony: 185-194), Wydawca: Narodowy Instytut Zdrowia Publicznego - Państwowy Zakład Higieny,
    Status:
    Published
  3. Badanie genetycznej zmienności szczepów Bordatella pertussis w aspekcie wzrostu zachorowań na krztusiec
    Authors:
    Lutyńska A., Mosiej E., Zawadka M., Polak M., Augustynowicz E
    Academic press:
    Problemy Higieny i Epidemiologii (rok: 2012, tom: 3, strony: 599-604), Wydawca: Polskie Towarzystwo Higieniczne
    Status:
    Published
  4. Consistency of Bordetella pertussis vaccine seed strains and potency of whole-cell pertussis vaccine still in use in Poland
    Authors:
    Zawadka M., Mosiej E., Polak M.,, Krysztopa-Grzybowska K., Moskała B., Rokosz-Chudziak N., Rabczenko D., Augustynowicz E., Lutyńska A.
    Academic press:
    Biologicals (rok: 2014, tom: 42, strony: 123-127), Wydawca: ELSEVIER
    Status:
    Published
    DOI:
    10.1016/j.biologicals.2013.11.006 - link to the publication