Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Analysis of protein mass profiles obtained by MALDI-ToF spectrometry to discover signatures of cancer

2011/01/N/NZ2/04813

Keywords:

MALDI-ToF pre-processing of biological data classification cancer signature

Descriptors:

  • NZ2_7: Bioinformatics
  • NZ2_3: Proteomics
  • NZ2_8: Computational biology

Panel:

NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution :

Politechnika Śląska, Wydział Automatyki, Elektroniki i Informatyki

woj. śląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Michał Marczyk 

Number of co-investigators in the project: 2

Call: PRELUDIUM 1 - announced on 2011-03-15

Amount awarded: 94 800 PLN

Project start date (Y-m-d): 2011-12-07

Project end date (Y-m-d): 2013-12-06

Project duration:: 24 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Wysokowydajnościowa karta graficzna (18 000 PLN)

Information in the final report

  • Publication in academic press/journals (1)
  • Articles in post-conference publications (6)
  • Book publications / chapters in book publications (1)
  1. Initializing the EM Algorithm for Univariate Gaussian, Multi-Component, Heteroscedastic Mixture Models by Dynamic Programming Partitions
    Authors:
    A.Polański, M.Marczyk, M.Pietrowska, P.Widlak, J.Polanska
    Academic press:
    International Journal of Computational Methods (rok: 2018, tom: 15, strony: 1850012), Wydawca: World Scientific
    Status:
    Published
    DOI:
    10.1142/S0219876218500123 - link to the publication
  1. A parallel implementation of MALDI-ToF spectra modeling on Cuda-enabled graphics hardware
    Authors:
    M.Marczyk, J.Polańska, A.Polański
    Conference:
    XVIIth Gliwice Scientific Meetings (rok: 2013, ), Wydawca: Centrum Onkologii w Gliwicach
    Data:
    konferencja 15-16.11.2013 r.
    Status:
    Published
  2. Detection and quantification of MALDI-ToF spectral peaks by using Gaussian mixture decomposition
    Authors:
    M.Marczyk, A.Polański, J.Polańska
    Conference:
    XVIth Gliwice Scientific Meetings (rok: 2012, ), Wydawca: Centrum Onkologii w Gliwicach
    Data:
    konferencja 16-17.11.2012 r.
    Status:
    Published
  3. Improving Peak Detection by Gaussian Mixture Modeling of Mass Spectral Signal
    Authors:
    M.Marczyk, A.Polański, J.Polańska
    Conference:
    3rd International Conference on Frontiers of Signal Processing (ICFSP 2017) (rok: 2017, ), Wydawca: Institute of Electrical and Electronics Engineers (IEEE)
    Data:
    konferencja 6-8.09
    Status:
    Published
  4. Automatic post-processing of Gaussian spectral components in MALDI-ToF data analysis
    Authors:
    M.Marczyk, J. Polańska, A. Polański
    Conference:
    Bioinformatics in Toruń (rok: 2012, ), Wydawca: nie dotyczy
    Data:
    konferencja 27-29.09.2012 r.
    Status:
    Published
  5. Batch effect detection methods in microarray data
    Authors:
    A.Molencka, M.Marczyk, J.Polańska
    Conference:
    XVth Gliwice Scientific Meetings (rok: 2011, ), Wydawca: Centrum Onkologii w Gliwicach
    Data:
    konferencja 18-19.11.2011
    Status:
    Published
  6. Peak detection by Gaussian mixture modeling of MALDI-ToF spectra for proteome profiling
    Authors:
    M.Marczyk, J.Polańska, A.Polański
    Conference:
    ISMB/ECCB 2013 (rok: 2013, ), Wydawca: nie dotyczy
    Data:
    konferencja 21-23.07.2013 r.
    Status:
    Published
  1. Comparison of algorithms for Profile-Based Alignment of low resolutions MALDI-ToF Spectra
    Authors:
    M.Marczyk, J.Polańska, A.Polański
    Book:
    Man Machine Interactions (rok: 2014, tom: 3, strony: 193-201), Wydawca: Springer International Publishing
    Status:
    Published