Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Sequence specificity and its determinants in dsRNA endoribonucleases

2011/01/B/NZ1/00209

Keywords:

sequence specificity RNA processing endonucleases

Descriptors:

  • NZ1_1: Molecular biology
  • NZ1_2: Biochemistry

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Krzysztof Skowronek 

Number of co-investigators in the project: 3

Call: OPUS 1 - announced on 2011-03-15

Amount awarded: 350 000 PLN

Project start date (Y-m-d): 2011-12-27

Project end date (Y-m-d): 2015-12-26

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Termocykler (20 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  1. Sequence-specific endoribonucleases
    Authors:
    D. Głów, M. Nowacka, K.J. Skowronek, J.M. Bujnicki
    Academic press:
    Postepy Biochemii (rok: 2016, tom: 62, strony: 303-314), Wydawca: Polskie Towarszystwo Biochemiczne
    Status:
    Published
  2. Sequence-specific cleavage of dsRNA by Mini-III RNase
    Authors:
    Głów D, Pianka D, Sulej A, Kozłowski ŁP, Czarnecka J, Chojnowski G, Skowronek KJ, Bujnicki JM
    Academic press:
    Nucleic Acids Research (rok: 2015, tom: 42, strony: 2864–2873), Wydawca: Oxford University Press
    Status:
    Published
    DOI:
    10.1093/nar/gkv009 - link to the publication
  3. Identification of protein structural elements responsible for the diversity of sequence preferences among Mini-III RNases
    Authors:
    Dawid Głów, M. Kurkowska, J. Czarnecka, K. Szczepaniak, Dariusz Pianka, Verena Kappert, Janusz M.Bujnicki, Krzysztof J. Skowronek
    Academic press:
    Scientific Reports (rok: 2016, tom: 6, strony: 38612), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/srep38612 - link to the publication