Projects funded by the NCN
Mitochondrial aldehyde dehydrogenase (ALDH2) as a new target for anti-atherosclerotic drugs
2011/01/N/NZ4/01145
Keywords:
atherosclerosis mitochondria ALDH2 proteomics
Descriptors:
- NZ4_17:
- NZ2_3: Proteomics
Panel:
NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology
Host institution :
Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Lekarski
woj. małopolskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 2
Call: PRELUDIUM 1 - announced on 2011-03-15
Amount awarded: 166 300 PLN
Project start date (Y-m-d): 2011-12-16
Project end date (Y-m-d): 2014-05-15
Project duration:: 29 months (the same as in the proposal)
Project status: Project settled
Equipment purchased [PL]
- MicroRotofor (35 000 PLN)
Information in the final report
- Publication in academic press/journals (1)
- Articles in post-conference publications (1)
- ALDH2 activation by Alda-1 inhibits atherosclerosis and attenuates hepatic steatosis in apoE-knockout miceAuthors:Aneta Stachowicz, Rafał Olszanecki, Maciej Suski, Anna Wiśniewska, Justyna Totoń-Żurańska, Józef Madej, Jacek Jawień, Magdalena Białas, Krzysztof Okoń, Mariusz Gajda, Katarzyna Głombik, Agnieszka Basta-Kaim, Ryszard KorbutAcademic press:Arteriosclerosis, Thrombosis, and Vascular Biology , Wydawca: American Heart AssociationStatus:SubmittedDOI:brak - link to the publication
- Proteomic analysis of liver mitochondria of atherosclerotic apoE-knockout mice treated with Alda-1 - an activator of mitochondrial aldehyde dehydrogenase (ALDH2)Authors:Aneta Stachowicz, Maciej Suski, Rafał Olszanecki, Józef Madej, Anna Wiśniewska, Jacek Jawień, Magdalena Białas, Krzysztof Okoń, Ryszard KorbutConference:XVIIIth International Congress of the Polish Pharmacology (rok: 2013, ), Wydawca: Institute of Pharmacology Polish Academy of SciencesData:konferencja 23-25 majaStatus:Published