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Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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THE EFFECT OF CHRONIC ADMINISTRATION OF SELECTED NEW ANTIEPILEPTIC DRUGS: OXCARBAZEPINE, LAMOTRIGINE, AND TOPIRAMATE ON THEIR ANTICONVULSANT PROPERTIES AGAINST THE MAXIMAL ELECTROSHOCK AND THE PROFILE OF UNDESIRED EFFECTS IN MICE

2011/01/B/NZ4/00369

Keywords:

oxcarbazepine lamotrigine topiramate seizures maximal electroshock motor impairment long-term memory deficit chronic administration

Descriptors:

  • NZ4_17:
  • NZ4_4: Pathophysiology

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Uniwersytet Medyczny w Lublinie, II Wydział Lekarski z Oddziałem Anglojęzycznym

woj. lubelskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Kinga Borowicz-Reutt 

Number of co-investigators in the project: 4

Call: OPUS 1 - announced on 2011-03-15

Amount awarded: 135 000 PLN

Project start date (Y-m-d): 2011-12-15

Project end date (Y-m-d): 2014-12-14

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. nie dotyczy.

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (2)
  1. Effects of chronic lamotrigine administration on maximal electroshock-induced seizures in mice
    Authors:
    Monika Banach, Kinga K. Borowicz
    Academic press:
    CNS & Neurological Disorders-Drug Targets (rok: 2015, tom: 14(7), strony: 855-62), Wydawca: Bentham Science Publishers
    Status:
    Published
    DOI:
    brak - link to the publication
  2. Vague effects of chronic topiramate administration on maximal electroshock-induced seizures in mice
    Authors:
    Monika Banach, Paweł Szpot, Grzegorz Buszewicz, Kinga K. Borowicz
    Academic press:
    Pharmacological Reports (rok: 2014, tom: 66(5), strony: 852-5), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.pharep.2014.05.006 - link to the publication
  1. The effectiveness and therapeutic index of chronic topiramate in the mouse maximal electroshock seizure test
    Authors:
    Kinga K. Borowicz
    Conference:
    2nd International Conference & Exhibition on Neurology and Therapeutics (rok: 2013, ), Wydawca: Journal of Neurology & Neurophysiology
    Data:
    konferencja 17-19.06.
    Status:
    Published
  2. The effectiveness and therapeutic index of oxcarbazepine and lamotrigine in the mouse maximal electroshock seizure test changes with the length and frequency of treatment
    Authors:
    Kinga K Borowicz, Monika Banach
    Conference:
    International League against Epilepsy 2nd African Epilepsy Congress (rok: 2014, ), Wydawca: International League against Epilepsy
    Data:
    konferencja 22-24.05
    Status:
    Published

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