Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The effect of kynurenic acid on signaling pathways in colon cancer cells - the evaluation of chemopreventive potential

2011/01/N/NZ4/01131

Keywords:

kynurenic acid cancer chemoprevention colon cancer signaling pathways

Descriptors:

  • NZ4_11: Metabolism

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Uniwersytet Medyczny w Lublinie, Wydział Pielęgniarstwa i Nauk o Zdrowiu

woj. lubelskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Katarzyna Walczak 

Number of co-investigators in the project: 2

Call: PRELUDIUM 1 - announced on 2011-03-15

Amount awarded: 102 500 PLN

Project start date (Y-m-d): 2011-12-16

Project end date (Y-m-d): 2013-12-15

Project duration:: 24 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. nie dotyczy.

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (2)
  1. Kynurenic acid inhibits colon cancer proliferation in vitro: effects on signaling pathways
    Authors:
    Katarzyna Walczak, Waldemar A. Turski, Grażyna Rajtar
    Academic press:
    Amino Acids (rok: 2014, tom: 46(10), strony: 2393-2401), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00726-014-1790-3 - link to the publication
  2. Kynurenic acid inhibits proliferation and migration of human glioblastoma T98G cells
    Authors:
    Katarzyna Walczak, Sylwia Deneka-Hannemann, Bożena Jarosz, Wojciech Zgrajka, Filip Stoma, Tomasz Trojanowski, Waldemar A. Turski, Wojciech Rzeski
    Academic press:
    Pharmacological Reports (rok: 2014, tom: 66, strony: 130-136), Wydawca: Elsevier, Instytut Farmakologii Polskiej Akademii Nauk
    Status:
    Published
    DOI:
    10.1016/j.pharep.2013.06.007 - link to the publication
  3. Kynurenic acid and cancer - facts and controversies
    Authors:
    Katarzyna Walczak, Waldemar A. Turski, Grażyna Rajtar
    Academic press:
    Anti-Cancer Agents in Medicinal Chemistry (rok: 2014, tom: nie dotyczy, strony: nie dotyczy), Wydawca: Bentham Science Publishers
    Status:
    Submitted
  1. Kwas kynureninowy jako modulator szlaku sygnałowego ERK w komórkach gruczolakoraka jelita grubego HT-29 - ocena potencjału chemoprewencyjnego
    Authors:
    Katarzyna Walczak, Waldemar A. Turski, Grażyna Rajtar
    Conference:
    VIII Konferencja Naukowa "Aktualne problemy biologii medycznej" Kazimierz Dolny (rok: 2013, ), Wydawca: Wydawnictwo EDYCJA s.c.
    Data:
    konferencja 16-19 maja 2013 r.
    Status:
    Published
  2. Kynurenic acid, a tryptophan metabolite, inhibits Akt kinase in human colon cancer HT-29 cells
    Authors:
    Katarzyna Walczak, Waldemar A. Turski, Grażyna Rajtar
    Conference:
    Cancer and Metabolism 2013, Amsterdam, Holandia (rok: 2013, ), Wydawca: Abcam plc
    Data:
    konferencja 24-25 czerwca 2013 r.
    Status:
    Published