Projects funded by the NCN


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120 projects found matching your search criteria :

  1. Structural determinants of anticancer properties of G-rich oligonucleotides

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: dr hab. Anna Pasternak

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  2. The characteristic of the regulatory RNAs landscape in glioblastoma multiforme (GBM). Circular RNAs and micro RNA-like m...

    Call: SONATA BIS 7 , Panel: NZ3

    Principal investigator: dr hab. Katarzyna Rolle

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  3. Molecular basics of type II transmembrane serine proteases (TTSPs)-mediated activation of influenza viruses

    Call: BEETHOVEN LIFE 1 , Panel: NZ1

    Principal investigator: dr Paweł Zmora

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  4. The cellular RNA interactome of the human Dicer helicase domain

    Call: PRELUDIUM 20 , Panel: NZ2

    Principal investigator: Kinga Ciechanowska

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  5. Investigation of a new therapeutic strategy to lower mutant protein in SCA3 / MJD

    Call: OPUS 21 , Panel: NZ2

    Principal investigator: dr hab. Maciej Figiel

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  6. New mechanisms determining MFT-mediated sensitivity to abscisic acid during the germination of Medicago truncatula seeds

    Call: OPUS 22 , Panel: NZ3

    Principal investigator: dr Joanna Banasiak

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  7. Structure-guided design of histone demethylase inhibitors for cancer therapy.

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Piotr Małecki

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  8. The role of transposable elements and epigenetic regulation of gene expression in Medicago truncatula root nodules devel...

    Call: PRELUDIUM BIS 3 , Panel: NZ2

    Principal investigator: dr hab. Agnieszka Żmieńko

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  9. Thermodynamics of modified RNAs. Impact of RNA modifications on structure and function of natural RNA and vaccine-type i...

    Call: OPUS 23 , Panel: ST4

    Principal investigator: prof. Ryszard Kierzek

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  10. tRNA-derived fragments as stress responsive and regulating agents in soybean

    Call: OPUS 24 , Panel: NZ9

    Principal investigator: dr Agata Tyczewska

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  11. Molecular mechanism of atherosclerosis progression in chronic kidney disease

    Call: OPUS 10 , Panel: NZ2

    Principal investigator: dr hab. Magdalena Łuczak

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  12. The APOBEC3B deletion - analysis of its role in familial breast cancer predisposition and determination of its consequen...

    Call: PRELUDIUM 10 , Panel: NZ5

    Principal investigator: dr Katarzyna Klonowska

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  13. Anticoagulant and antiproliferative properties of novel thrombin binding aptamer analogues

    Call: PRELUDIUM 10 , Panel: NZ5

    Principal investigator: Weronika Kotkowiak

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  14. Identification of CAG repeat-binding proteins and imaging RNA-protein interactions in cells

    Call: OPUS 10 , Panel: NZ2

    Principal investigator: dr Adam Ciesiołka

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  15. Impact of noncoding RNAs on renal cell development and carcinogenesis

    Call: OPUS 11 , Panel: NZ2

    Principal investigator: dr hab. Jan Wrzesiński

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  16. Interspecies metabolic engineering as a tool to investigate immune functions of plant specialized metabolites.

    Call: OPUS 18 , Panel: NZ1

    Principal investigator: dr hab. Paweł Bednarek

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  17. Foldback triplex-forming oligonucleotides as novel tools for G-quadruplex unfolding and selective inhibition of c-Myc on...

    Call: OPUS 19 , Panel: NZ7

    Principal investigator: dr hab. Anna Pasternak

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  18. Kinetin riboside and its derivatives-analysis of apoptotic properties and mechanism of action in brain tumor cells

    Call: OPUS 7 , Panel: NZ7

    Principal investigator: dr hab. Eliza Wyszko

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  19. (Micro)RNA and informatics approaches for diagnosis, prognosis and treatment of Alzheimer's disease and Dementia

    Call: JPND Call 2023 , Panel: NZ3

    Principal investigator: dr hab. Agnieszka Fiszer

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  20. In search for DNA methylation aberrations associated with susceptibility to ovarian cancer

    Call: OPUS 26 , Panel: NZ5

    Principal investigator: dr Malwina Suszyńska

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  21. Lanthanide binding oligonucleotides (LBOs) as paramagnetic tags for NMR spectroscopy of nucleic acids

    Call: OPUS 19 , Panel: ST4

    Principal investigator: dr Witold Andrałojć

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  22. Input of the structure of influenza A virus RNA on regulation of virus proliferation. High throughput screening of small...

    Call: OPUS 20 , Panel: NZ1

    Principal investigator: prof. Elżbieta Kierzek

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  23. Long noncoding RNA - new aim of anti-influenza therapy

    Call: SONATA 16 , Panel: NZ6

    Principal investigator: dr Marta Soszyńska-Jóźwiak

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  24. Anti-cancer strategy based on the induced G-quadruplex formation. Structural and biological properties of ligand-RNA/mRN...

    Call: SONATA 16 , Panel: ST4

    Principal investigator: dr Dorota Gudanis

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  25. Function and dysfunction of repeated tracts in non-coding and protein-coding transcripts

    Call: OPUS 21 , Panel: NZ3

    Principal investigator: dr hab. Agnieszka Fiszer

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  26. Airborne microbiome - characterization of microorganisms inhabiting particulate matter of urban areas and their impact o...

    Call: OPUS 21 , Panel: NZ9

    Principal investigator: dr Anna Philips

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  27. The use of artificial miRNAs in the therapy of Huntington's Disease

    Call: PRELUDIUM 20 , Panel: NZ1

    Principal investigator: Anna Kotowska-Zimmer

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  28. Crystallographic analysis of RNA-ligand complexes. Towards rational design oflead compounds for development of therapies...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Kiliszek

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  29. Unknown areas of activity of human ribonuclease Dicer

    Call: SONATA BIS 6 , Panel: NZ1

    Principal investigator: dr hab. Anna Kurzyńska-Kokorniak

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  30. Analysis of somatic mutations in miRNA and miRNA-biogenesis genes to identify new therapeutic targets and biomarkers of ...

    Call: MAESTRO 8 , Panel: NZ2

    Principal investigator: prof. Piotr Kozłowski

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  31. Copy number polymorphism of microRNA genes in Arabidopsis thaliana accessions and its impact on the post-transcriptional...

    Call: PRELUDIUM 13 , Panel: NZ2

    Principal investigator: dr Anna Samelak-Czajka

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  32. Identification of biomolecules released by colorectal cancer cells and detected in serum or/and exosomes

    Call: SONATA 13 , Panel: NZ2

    Principal investigator: dr hab. Anna Wojakowska

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  33. Contribution of gene copy number polymorphism to natural variation in response of Arabidopsis thaliana ecotypes to bioti...

    Call: SONATA 13 , Panel: NZ2

    Principal investigator: dr hab. Agnieszka Żmieńko

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  34. Mechanisms of human gene expression regulation by uridilation

    Call: SONATA 13 , Panel: NZ1

    Principal investigator: dr hab. Zbigniew Warkocki

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  35. In vivo and in vitro structure of influenza virus RNA. The structural determinants behind the inhibition of influenza vi...

    Call: OPUS 10 , Panel: NZ1

    Principal investigator: prof. Elżbieta Kierzek

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  36. The role of membrane transporters in the cytokinin signaling upon Legume- Rhizobia Symbiosis

    Call: OPUS 10 , Panel: NZ9

    Principal investigator: dr hab. Michał Jasiński

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  37. Cytoplasmatic roadblocks in cell fate reprogramming: from players to molecular mechanisms

    Call: OPUS 10 , Panel: NZ3

    Principal investigator: dr hab. Rafał Ciosk

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  38. Impact of subcellular localization on the specificity of selected enzymes involved in the biosynthesis and metabolism of...

    Call: OPUS 16 , Panel: NZ3

    Principal investigator: prof. Paweł Bednarek

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  39. Mechanisms and developmental roles of transcription termination

    Call: OPUS 16 , Panel: NZ1

    Principal investigator: dr hab. Takashi Miki

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  40. Exploring second generation of nucleotide analogues containing phosphoranesulfen- or phosphoraneselenamides as new struc...

    Call: PRELUDIUM 16 , Panel: ST5

    Principal investigator: dr Justyna Gołębiewska

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  41. Defining roles of LINE-1 mRNA 5' and 3' ends in the retrotransposon biology

    Call: OPUS 17 , Panel: NZ1

    Principal investigator: dr Zbigniew Warkocki

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  42. Design and Development of Serine Hydroxymethyltransferase-2 (SHMT2) Inhibitors Blocking Tumor Growth

    Call: SONATA BIS 13 , Panel: NZ7

    Principal investigator: dr hab. Miłosz Ruszkowski

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  43. Insights in the phenylpropanoid transport in model legume plant Medicago truncatula

    Call: SONATA 19 , Panel: NZ9

    Principal investigator: dr Wanda Biała-Leonhard

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  44. Comprehensive analysis of the Schmidtea mediterranea transcriptome – identification of non-coding RNAs involved in cell ...

    Call: OPUS 18 , Panel: NZ2

    Principal investigator: dr hab. Paulina Jackowiak

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  45. Antibiotic resistance genes and integrons as indicators of biotic pollution and resistance load of Arctic ecosystems

    Call: SONATINA 4 , Panel: NZ9

    Principal investigator: dr Nicoletta Makowska

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  46. The role of protein factors that bind to the 5' non-coding region of human p53 mRNA in regulation of p53 expression at t...

    Call: OPUS 11 , Panel: NZ1

    Principal investigator: prof. Jerzy Ciesiołka

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  47. Modified siRNAs, ribozymes and CRISPR/Cas system as strategies for influenza A virus inhibition. Application and compari...

    Call: PRELUDIUM 11 , Panel: NZ1

    Principal investigator: dr Julita Piasecka

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  48. Histone demethylase JMJD3 as an epigenetic regulator in the senescence-associated secretory phenotype and cancer

    Call: SONATA 11 , Panel: NZ3

    Principal investigator: dr Patrick Perrigue

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  49. N-Oxide phosphobetaines in new synthetic strategies for P-modified phosphates and polyphospates of natural biomolecules ...

    Call: PRELUDIUM 12 , Panel: ST5

    Principal investigator: Magdalena Materna

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  50. Relationship between ATPase activity stimulation and transport - the case of selective Medicago truncatula ABCG transpor...

    Call: PRELUDIUM 20 , Panel: NZ1

    Principal investigator: Konrad Pakuła

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk