Projects funded by the NCN


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100 projects found matching your search criteria :

  1. Cognitive impairment in chronic pain - CBD as the undervalued remedy.

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: prof. Katarzyna Starowicz-Bubak

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  2. The role of simultaneous and individual modulation of μ-opioid, sigma-1 and histamine H3 receptors as a new therapeutic ...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: dr Katarzyna Szczepańska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  3. The role of codependent 5-HT1a and 5-HT7 receptor signalling in the hippocampal stress response

    Call: PRELUDIUM 12 , Panel: NZ4

    Principal investigator: Marcin Siwiec

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  4. Impact of early-life stress on maturation, permeability of blood brain-barrier and neuroinflammatory processes activatio...

    Call: PRELUDIUM 12 , Panel: NZ4

    Principal investigator: Anna Solarz

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  5. The role of brain glutamatergic system in the neuroendocrine regulation of cytochrome P450 expression and activity in th...

    Call: OPUS 12 , Panel: NZ7

    Principal investigator: prof. Władysława Daniel

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  6. Zinc Deficiency: An essential Variable for the Induction od Resistance to Antidepressants

    Call: PRELUDIUM 13 , Panel: NZ5

    Principal investigator: dr Anna Rafało-Ulińska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  7. Altered interaction between NMDA receptor subunits and their scaffolding proteins as a critical step to control drug see...

    Call: OPUS 9 , Panel: NZ7

    Principal investigator: prof. Małgorzata Filip

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  8. Simultaneous stimulation of muscarinic M4 receptor and selected receptors involved in the regulation of glutamate releas...

    Call: OPUS 9 , Panel: NZ7

    Principal investigator: dr hab. Joanna Wierońska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  9. Role of the NLRP3 inflammasome in the mechanisms of action of antidepressant drugs - study in an animal model of depress...

    Call: PRELUDIUM 9 , Panel: NZ7

    Principal investigator: dr Ewa Trojan

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  10. The role of the endogenuous opioid system in prosocial behavior

    Call: OPUS 11 , Panel: NZ4

    Principal investigator: dr hab. Jan Rodriguez Parkitna

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  11. Modified maternal diet as a factor of autism spectrum disorders in offspring - preclinical molecular studies on prefront...

    Call: PRELUDIUM 15 , Panel: NZ7

    Principal investigator: Kinga Gawlińska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  12. Rational design and evaluation of functionally biased opioid agonists

    Call: OPUS 16 , Panel: NZ7

    Principal investigator: prof. Ryszard Przewłocki

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  13. Impact of maternal monosaccharide diet on dams and offspring hippocampus development.

    Call: PRELUDIUM 22 , Panel: NZ1

    Principal investigator: Kacper Witek

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  14. Optogenetic and chemogenetic identification of brain circuits and cellular mechanisms underlying antidepressants resista...

    Call: OPUS 26 , Panel: NZ7

    Principal investigator: prof. Mariusz Papp

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  15. Kappa opioid receptors integrate neuronal signaling involved in social behavior

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: dr hab. Jan Rodriguez Parkitna

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  16. Investigation of novel functionally selective opioid receptors agonists

    Call: ETIUDA 8 , Panel: NZ7

    Principal investigator: Łucja Kudła

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  17. The effect of the metabotropic glutamatergic receptor ligands on potentiating the antidepressant-like actvity of scopola...

    Call: PRELUDIUM 10 , Panel: NZ7

    Principal investigator: Karolina Podkowa

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  18. The role of selected signaling pathways in zinc deficiency

    Call: OPUS 10 , Panel: NZ4

    Principal investigator: prof. Gabriel Nowak

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  19. Pharmacological properties and neurotoxicity of novel NBOMe derivatives

    Call: OPUS 11 , Panel: NZ7

    Principal investigator: prof. Krystyna Gołembiowska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  20. Genetics of GR-dependent behavioral traits in humans

    Call: OPUS 23 , Panel: NZ5

    Principal investigator: dr hab. Michał Korostyński

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  21. The cross-talk between 5-HTR2A and mGluR2 as a window for antidepressant effects of psilocybin.

    Call: OPUS 25 , Panel: NZ7

    Principal investigator: prof. Andrzej Pilc

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  22. ROS-Scavenging Magnetic Nanozymes with Remote Activation for Alzheimer Disease

    Call: M-ERA.NET 3 Call 2023 , Panel: NZ5

    Principal investigator: dr hab. Anna Haduch

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  23. Potential pharmacological strategies aimed at alleviating cognitive dysfunctions accompanying oncological therapy while ...

    Call: OPUS 26 , Panel: NZ5

    Principal investigator: dr hab. Joanna Wierońska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  24. Pharmacological modulation of histamine H3 and H4 receptors - a new perspective in the treatment of neuropathic pain

    Call: SONATA 15 , Panel: NZ7

    Principal investigator: dr Katarzyna Popiołek-Barczyk

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  25. Fluorine substitution – a new algorithm for increasing biological activity

    Call: PRELUDIUM 18 , Panel: NZ7

    Principal investigator: Wojciech Pietruś

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  26. Investigation of molecular mechanisms of rapid antidepressant action of NLX-101, a biased agonist of the 5-HT1A receptor...

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: prof. Mariusz Papp

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  27. Dual histamine H3 and sigma-1 receptor ligands as novel pharmacological tools in the treatment of central nervous system...

    Call: SONATINA 4 , Panel: NZ7

    Principal investigator: Katarzyna Szczepańska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  28. Neurochemical basis of antidepressive properties of psychedelics in rodent model of depression

    Call: OPUS 19 , Panel: NZ7

    Principal investigator: prof. Krystyna Gołembiowska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  29. Modulation of inflammatory processes using new agonists of the formyl peptide receptors ALX/FPR2 as a new therapeutic st...

    Call: HARMONIA 9 , Panel: NZ7

    Principal investigator: prof. Agnieszka Basta-Kaim

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  30. How microglia-astrocyte interaction affects neuronal functioning in the dopaminergic system. Analysis of the protective ...

    Call: OPUS 14 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Kuter-Nowak

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  31. The role of cognitive bias in individual vulnerability to to the transition from controlled use to uncontrolled abuse of...

    Call: OPUS 16 , Panel: NZ7

    Principal investigator: dr hab. Rafał Ryguła

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  32. Development of a comprehensive set of computational tools for the search of new ligands of particular receptor - case st...

    Call: OPUS 16 , Panel: NZ2

    Principal investigator: dr hab. Sabina Podlewska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  33. The influence of muscarinic acetylcholine receptors (M1, M4 and M5) and serotonergic 5-HT1A receptor modulation on cogni...

    Call: PRELUDIUM 16 , Panel: NZ7

    Principal investigator: dr Paulina Cieślik

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  34. Effects of chosen chemokines on the activity and synaptic transmission in central and basolateral complex of the amygdal...

    Call: PRELUDIUM 11 , Panel: NZ4

    Principal investigator: Joanna Sowa

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  35. Modulation of amygdala neural network activity by the 5-HT7 receptor

    Call: OPUS 11 , Panel: NZ4

    Principal investigator: prof. Krzysztof Tokarski

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  36. Sensitivity to negative feedback as a cognitive biomarker of depression in an animal model

    Call: OPUS 12 , Panel: NZ4

    Principal investigator: dr hab. Rafał Ryguła

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  37. The effects of thyroid hormones in the brain in an animal model of depression

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: prof. Bogusława Budziszewska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  38. Development of unique molecular probes: low-basicity agonists for the study of 5-HT7 receptor function

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: prof. Andrzej Bojarski

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  39. Maternal obesity as a risk factor of autism spectrum disorder in offspring - in search of the role of the gut microbiota...

    Call: OPUS 22 , Panel: NZ5

    Principal investigator: dr Dawid Gawliński

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  40. New approach to the treatment of Alzheimer's disease targetingresolution of inflammation and modulation of biomechanical...

    Call: OPUS 22 , Panel: NZ4

    Principal investigator: prof. Agnieszka Basta-Kaim

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  41. Brain cytochrome P450 as a new target for the treatment of neurological and psychiatric diseases. Studies with human neu...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: prof. Władysława Daniel

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  42. Selective PPARγ modulation by amorfrutin B as a novel therapeutic approach to chemotherapy-induced damage to mammalian b...

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: Bernadeta Pietrzak-Wawrzyńska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  43. Plasticity of neuroanatomically identified synaptic inputs and functions of the dorsal raphe nucleus in an animal model ...

    Call: OPUS 25 , Panel: NZ4

    Principal investigator: prof. Krzysztof Tokarski

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  44. Influence of modified maternal diet on the phenotype of offspring: behavioral and molecular correlations

    Call: ETIUDA 8 , Panel: NZ7

    Principal investigator: Kinga Gawlińska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  45. Spatial analysis of the effects of L-DOPA on gene expression in the prefrontal cortex in a mouse model of Parkinson's di...

    Call: PRELUDIUM 19 , Panel: NZ4

    Principal investigator: Anna Radlicka

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  46. Investigating the role of the focal adhesion kinase and its related signaling pathways in glucocorticoid- and stress-ind...

    Call: PRELUDIUM 20 , Panel: NZ4

    Principal investigator: Michał Wilczkowski

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  47. The influence of perinatal exposure to selective serotonin reuptake inhibitors on the structure and functions of mice do...

    Call: OPUS 14 , Panel: NZ4

    Principal investigator: prof. Grzegorz Hess

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  48. Opioid-induced analgesia and hyperalgesia in neuropathic pain - mechanisms and druggable targets

    Call: OPUS 15 , Panel: NZ7

    Principal investigator: prof. Barbara Przewłocka

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  49. Investigation of the effects and mechanisms of action of Deep Brain Stimulation in two animal models of treatment-resist...

    Call: OPUS 9 , Panel: NZ7

    Principal investigator: prof. Mariusz Papp

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  50. The role of kynurenine pathway in neurophatic pain in view of innovative treatment approaches

    Call: SONATA 9 , Panel: NZ4

    Principal investigator: dr Ewelina Rojewska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk