Projects funded by the NCN

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103 projects found matching your search criteria :

  1. Determination of the mechanisms and potential targets for neuropathic pain therapy by investigating pharmacological inte...

    Call: PRELUDIUM 12 , Panel: NZ7

    Principal investigator: Anna Piotrowska-Murzyn

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  2. The role of codependent 5-HT1a and 5-HT7 receptor signalling in the hippocampal stress response

    Call: PRELUDIUM 12 , Panel: NZ4

    Principal investigator: Marcin Siwiec

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  3. The effects of thyroid hormones in the brain in an animal model of depression

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: prof. Bogusława Budziszewska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  4. Pharmacological and optogenetic investigation of the mechanism of action of Deep Brain Stimulation of the ventromedial p...

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: prof. Mariusz Papp

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  5. Modulation of inflammatory processes using new agonists of the formyl peptide receptors ALX/FPR2 as a new therapeutic st...

    Call: HARMONIA 9 , Panel: NZ7

    Principal investigator: prof. Agnieszka Basta-Kaim

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  6. The role of selected metabotropic glutamate receptors in the mechanism of rapid antidepressant effect of RS-ketamine and...

    Call: OPUS 14 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Pałucha-Poniewiera

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  7. Ocena roli wybranych białek neuronalnych i mikroglejowych w patogenezie schizofrenii - badania w modelu zwierzęcym.

    Call: ETIUDA 7 , Panel: NZ4

    Principal investigator: Katarzyna Chamera

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  8. Dual histamine H3 and sigma-1 receptor ligands as novel pharmacological tools in the treatment of central nervous system...

    Call: SONATINA 4 , Panel: NZ7

    Principal investigator: Katarzyna Anna Szczepańska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  9. Zinc deficient diet as a trigger for treatment-resistant depression in chronically stressed mice. Understanding the mech...

    Call: OPUS 19 , Panel: NZ5

    Principal investigator: dr hab. Bernadeta Szewczyk

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  10. Selective activation of non-nuclear Estrogen Receptor signaling with PaPE-1 as a novel therapeutic approach for sporadic...

    Call: OPUS 20 , Panel: NZ7

    Principal investigator: prof. Małgorzata Kajta

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  11. Translational and interdisciplinary investigation of phenotypes of reinforcement sensitivity as predictors of the respon...

    Call: OPUS 22 , Panel: HS6

    Principal investigator: dr hab. Rafał Ryguła

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  12. Genetics of GR-dependent behavioral traits in humans

    Call: OPUS 23 , Panel: NZ5

    Principal investigator: dr hab. Michał Korostyński

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  13. Selective PPARγ modulation by amorfrutin B as a novel therapeutic approach to chemotherapy-induced damage to mammalian b...

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: Bernadeta Pietrzak

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  14. Impact of maternal monosaccharide diet on dams and offspring hippocampus development.

    Call: PRELUDIUM 22 , Panel: NZ1

    Principal investigator: Kacper Witek

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  15. ROS-Scavenging Magnetic Nanozymes with Remote Activation for Alzheimer Disease

    Call: M-ERA.NET 3 Call 2023 , Panel: NZ5

    Principal investigator: dr hab. Anna Haduch

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  16. Optogenetic and chemogenetic identification of brain circuits and cellular mechanisms underlying antidepressants resista...

    Call: OPUS 26 , Panel: NZ7

    Principal investigator: prof. Mariusz Papp

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  17. "Epigenetic mechanisms underlying cocaine seeking and relapse"

    Call: MAESTRO 3 , Panel: NZ3

    Principal investigator: prof. Małgorzata Filip

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  18. The role of kynurenine pathway in neurophatic pain in view of innovative treatment approaches

    Call: SONATA 9 , Panel: NZ4

    Principal investigator: dr Ewelina Rojewska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  19. Changes in neurogenesis during withdrawal from nicotine self-administration in rats - role of serotonin (5-HT)2C recepto...

    Call: OPUS 9 , Panel: NZ4

    Principal investigator: dr Magdalena Zaniewska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  20. Comparative effects of 1-methyl-1,2,3,4-tetrahydroisoquinoline (1MeTIQ) and olanzapine on the cognitive dysfunction meas...

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Wąsik

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  21. New post-treatment strategy against stroke and perinatal asphyxia – a novel approach based on a selective activation of ...

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Agnieszka Wnuk

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  22. The role of simultaneous and individual modulation of μ-opioid, sigma-1 and histamine H3 receptors as a new therapeutic ...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: dr Katarzyna Anna Szczepańska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  23. The developmental changes in the endogenous opioid system associated with altered sensitivity to reward during adolescen...

    Call: PRELUDIUM 21 , Panel: NZ4

    Principal investigator: Klaudia Weronika Misiołek

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  24. Early-life programming for neurodevelopmental disorders: search for a prodrome target within the vascular network in a r...

    Call: OPUS 23 , Panel: NZ4

    Principal investigator: prof. Małgorzata Filip

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  25. "I like to move it, move it" – molecular dynamics-driven optimization of ligand residence time as an opportunity to impr...

    Call: OPUS 25 , Panel: NZ7

    Principal investigator: dr hab. Sabina Podlewska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  26. Opioid-induced analgesia and hyperalgesia in neuropathic pain - mechanisms and druggable targets

    Call: OPUS 15 , Panel: NZ7

    Principal investigator: prof. Barbara Przewłocka

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  27. Development of a comprehensive set of computational tools for the search of new ligands of particular receptor - case st...

    Call: OPUS 16 , Panel: NZ2

    Principal investigator: dr hab. Sabina Podlewska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  28. Rational design and evaluation of functionally biased opioid agonists

    Call: OPUS 16 , Panel: NZ7

    Principal investigator: prof. Ryszard Przewłocki

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  29. Effects of a novel nonaddictive opioid on response to stress

    Call: PRELUDIUM 17 , Panel: NZ7

    Principal investigator: dr Łucja Elżbieta Szumiec

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  30. Kappa opioid receptors integrate neuronal signaling involved in social behavior

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: dr hab. Jan Manuel Rodriguez Parkitna

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  31. Fluorine substitution – a new algorithm for increasing biological activity

    Call: PRELUDIUM 18 , Panel: NZ7

    Principal investigator: Wojciech Pietruś

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  32. Investigation of novel functionally selective opioid receptors agonists

    Call: ETIUDA 8 , Panel: NZ7

    Principal investigator: Łucja Elżbieta Szumiec

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  33. Influence of modified maternal diet on the phenotype of offspring: behavioral and molecular correlations

    Call: ETIUDA 8 , Panel: NZ7

    Principal investigator: Kinga Gawlińska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  34. Spatial analysis of the effects of L-DOPA on gene expression in the prefrontal cortex in a mouse model of Parkinson's di...

    Call: PRELUDIUM 19 , Panel: NZ4

    Principal investigator: dr Anna Aleksandra Radlicka-Borysewska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  35. The effect of omega-3 fatty acid-enriched diet on the myelination impairment and the depression-like phenotype induced b...

    Call: SONATA 16 , Panel: NZ5

    Principal investigator: dr Irena Maria Smaga-Maślanka

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  36. Involvement of astrocytes in the neuroprotective mechanism evoked by enhancement of noradrenergic transmission in trasng...

    Call: PRELUDIUM 18 , Panel: NZ7

    Principal investigator: Justyna Beata Barut

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  37. Evaluation of molecular mechanisms of neuroprotective action of dental pulp stromal cells in an ex vivo organotypic mode...

    Call: PRELUDIUM 18 , Panel: NZ7

    Principal investigator: dr Natalia Helena Bryniarska-Kubiak

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  38. Physical exercise as a natural mechanism inducing neuroregeneration. Search for the new protein markers and therapeutic ...

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Zofia Kuter-Nowak

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  39. Combined administration of muscarinic receptor antagonists and group II/III metabotropic glutamate (mGlu) receptor ligan...

    Call: OPUS 19 , Panel: NZ7

    Principal investigator: prof. Andrzej Mikołaj Pilc

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  40. Neurochemical basis of antidepressive properties of psychedelics in rodent model of depression

    Call: OPUS 19 , Panel: NZ7

    Principal investigator: prof. Krystyna Czesława Gołembiowska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  41. Prenatal exposure to glucocorticoids as a risk factor for depression - the importance of epigenetic mechanisms in the br...

    Call: SONATA 16 , Panel: NZ7

    Principal investigator: dr Katarzyna Elżbieta Głombik

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  42. Investigating the role of the focal adhesion kinase and its related signaling pathways in glucocorticoid- and stress-ind...

    Call: PRELUDIUM 20 , Panel: NZ4

    Principal investigator: Michał Józef Wilczkowski

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  43. Novel hope for diseased joints: a polymer-based treatment to promoteregenerative strategies for patients with osteoarthr...

    Call: PRELUDIUM 20 , Panel: NZ7

    Principal investigator: Marta Kędziora

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  44. The role of the immune checkpoints in the pathomechanism of depressive disorders.

    Call: OPUS 22 , Panel: NZ6

    Principal investigator: prof. Marta Wanda Kubera

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  45. Brain GABAB receptors as determinants of obesity phenotypes: evaluation of adolescent female and male rats

    Call: OPUS 22 , Panel: NZ5

    Principal investigator: prof. Małgorzata Maria Filip

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  46. Biological roles of transcriptional networks activated in the brain by psychotropic drugs

    Call: PRELUDIUM BIS 3 , Panel: NZ7

    Principal investigator: dr hab. Michał Korostyński

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  47. The evaluation of the efficacy of alpha7 nicotinic acetylcholine receptor ligands in rat models of autism

    Call: OPUS 12 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Nikiforuk

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  48. Sensitivity to negative feedback as a cognitive biomarker of depression in an animal model

    Call: OPUS 12 , Panel: NZ4

    Principal investigator: dr hab. Rafał Ryguła

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  49. The role of brain glutamatergic system in the neuroendocrine regulation of cytochrome P450 expression and activity in th...

    Call: OPUS 12 , Panel: NZ7

    Principal investigator: prof. Władysława Daniel

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  50. Modified maternal diet as a factor of autism spectrum disorders in offspring - preclinical molecular studies on prefront...

    Call: PRELUDIUM 15 , Panel: NZ7

    Principal investigator: Kinga Gawlińska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

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