Projects funded by the NCN


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199 projects found matching your search criteria :

  1. The study of the role of mGluR8 in cancer cells - a potential target for new antitumor strategies

    Call: OPUS 3 , Panel: NZ3

    Principal investigator: dr Danuta Jantas

    Instytut Farmakologii PAN

  2. The group III metabotropic glutamate receptors as a target for future antypsychotic drugs

    Call: MAESTRO 3 , Panel: NZ7

    Principal investigator: prof. Andrzej Pilc

    Instytut Farmakologii PAN

  3. "Epigenetic mechanisms underlying cocaine seeking and relapse"

    Call: MAESTRO 3 , Panel: NZ3

    Principal investigator: prof. Małgorzata Maria Filip

    Instytut Farmakologii PAN

  4. PHARMACOTHERAPY OF OSTEOARTHRITIS: TRPV1 AND CB1 RECEPTORS AND THEIR ENDOGENOUS LIGANDS AS NEW TARGETS FOR PHARMACOLOGIC...

    Call: SONATA BIS 2 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Maria Starowicz-Bubak

    Instytut Farmakologii PAN

  5. Neurobiology of optimism; Characterisation of the neuroanatomical and neurochemical substrates of cognitive judgement bi...

    Call: SONATA BIS 2 , Panel: NZ4

    Principal investigator: dr hab. Rafał Ryguła

    Instytut Farmakologii PAN

  6. The research of molecular markers for neuroprotective effect of tetrahydroisoquinolines based on various eksperimental m...

    Call: OPUS 4 , Panel: NZ7

    Principal investigator: dr Agnieszka Wąsik

    Instytut Farmakologii PAN

  7. The effects of positive allosteric modulators of alpha7 nicotinic acetylcholine receptors on complex cognitive processes...

    Call: OPUS 4 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Anna Nikiforuk

    Instytut Farmakologii PAN

  8. The effect of imipramine and risperidone on regulation of the chronic mild stress-induced anhedonia and memory impairmen...

    Call: OPUS 5 , Panel: NZ7

    Principal investigator: dr hab. Mariusz Papp

    Instytut Farmakologii PAN

  9. Motor thalamic nuclei as a potential therapeutic target for adenosine in parkinsonian and essential tremor; behavioural,...

    Call: OPUS 6 , Panel: NZ4

    Principal investigator: dr hab. Jadwiga Wardas

    Instytut Farmakologii PAN

  10. The effect of the novel atypical neuroleptics on the activity and expression of cytochrome P450 isoforms in human liver

    Call: OPUS 6 , Panel: NZ7

    Principal investigator: dr hab. Jacek Wójcikowski

    Instytut Farmakologii PAN

  11. Contribution of nitrergic transmission in the modulation of L-dopa activity in the rat 6-OHDA model of Parkinson's disea...

    Call: OPUS 1 , Panel: NZ4

    Principal investigator: dr hab. Elżbieta Kazimiera Lorenc-Koci

    Instytut Farmakologii PAN

  12. Opioid receptors in the basal ganglia of the brain as targets for alcohol abuse therapy.

    Call: OPUS 2 , Panel: NZ4

    Principal investigator: dr Jan Manuel Rodriguez Parkitna

    Instytut Farmakologii PAN

  13. Molecular characteristics of stress-resilient phenotype using mice models.

    Call: OPUS 12 , Panel: NZ4

    Principal investigator: prof. Marta Dziedzicka-Wasylewska

    Instytut Farmakologii PAN

  14. Evaluation of the influence of progressive noradrenergic neurodegeneration on dopaminergic system functioning in context...

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: dr Grzegorz Kreiner

    Instytut Farmakologii PAN

  15. Zinc Deficiency: An essential Variable for the Induction od Resistance to Antidepressants

    Call: PRELUDIUM 13 , Panel: NZ5

    Principal investigator: dr Anna Maria Rafało-Ulińska

    Instytut Farmakologii PAN

  16. Modified maternal diet as a factor of autism spectrum disorders in offspring - preclinical molecular studies on prefront...

    Call: PRELUDIUM 15 , Panel: NZ7

    Principal investigator: Kinga Eryka Gawlińska

    Instytut Farmakologii PAN

  17. Altered interaction between NMDA receptor subunits and their scaffolding proteins as a critical step to control drug see...

    Call: OPUS 9 , Panel: NZ7

    Principal investigator: prof. Małgorzata Maria Filip

    Instytut Farmakologii PAN

  18. Simultaneous stimulation of muscarinic M4 receptor and selected receptors involved in the regulation of glutamate releas...

    Call: OPUS 9 , Panel: NZ7

    Principal investigator: dr hab. Joanna Monika Wierońska

    Instytut Farmakologii PAN

  19. The role of selected signaling pathways in zinc deficiency

    Call: OPUS 10 , Panel: NZ4

    Principal investigator: prof. Gabriel Piotr Nowak

    Instytut Farmakologii PAN

  20. Neurodevelopmental patomechanisms of triclocarban- and dichlorodiphenyldichloroetylene-induced effects: the role of apop...

    Call: OPUS 10 , Panel: NZ7

    Principal investigator: dr hab. Małgorzata Kajta

    Instytut Farmakologii PAN

  21. Searching for effective strategies to protect neuronal cells against hypoxia and ischemia: Identification of neuroprotec...

    Call: OPUS 16 , Panel: NZ7

    Principal investigator: prof. Małgorzata Kajta

    Instytut Farmakologii PAN

  22. The role of nitric oxide-dependent pathways in the procognitive effects of muscarinic and metabotropic glutamate recepto...

    Call: OPUS 17 , Panel: NZ7

    Principal investigator: dr hab. Joanna Monika Wierońska

    Instytut Farmakologii PAN

  23. Evaluation of molecular mechanisms of neuroprotective action of dental pulp stromal cells in an ex vivo organotypic mode...

    Call: PRELUDIUM 18 , Panel: NZ7

    Principal investigator: dr Natalia Helena Bryniarska-Kubiak

    Instytut Farmakologii PAN

  24. Research of mechanisms of antidepressant action of group II and III mGlu receptor ligands and their role in inducing rap...

    Call: OPUS 7 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Pałucha-Poniewiera

    Instytut Farmakologii PAN

  25. Evaluation of the role of transcription factor CREB in the mechanisms antidepressant treatment: study on the novel genet...

    Call: OPUS 7 , Panel: NZ7

    Principal investigator: dr Grzegorz Kreiner

    Instytut Farmakologii PAN

  26. The impact of maternal diabetes on inflammasome NLRP3 activation in the offspring brain

    Call: PRELUDIUM 7 , Panel: NZ7

    Principal investigator: dr Katarzyna Elżbieta Głombik

    Instytut Farmakologii PAN

  27. The effect of social stress during adolescence on the psychotic symptoms development and epigenetic mechanisms in the ne...

    Call: OPUS 7 , Panel: NZ4

    Principal investigator: dr hab. Marzena Małgorzata Maćkowiak

    Instytut Farmakologii PAN

  28. Znaczenie interakcji układu endokanabinoidowego i endowaniloidowego w leczeniu bólu przewlekłego - potencjał terapeutycz...

    Call: ETIUDA 3 , Panel: NZ7

    Principal investigator: Natalia Eleonora Małek

    Instytut Farmakologii PAN

  29. Spatial analysis of the effects of L-DOPA on gene expression in the prefrontal cortex in a mouse model of Parkinson's di...

    Call: PRELUDIUM 19 , Panel: NZ4

    Principal investigator: dr Anna Aleksandra Radlicka-Borysewska

    Instytut Farmakologii PAN

  30. Chronic pain in obesity: from cellular mechanisms to new strategies for targeted therapy.

    Call: SONATA 17 , Panel: NZ5

    Principal investigator: dr Anna Piotrowska-Murzyn

    Instytut Farmakologii PAN

  31. "I like to move it, move it" – molecular dynamics-driven optimization of ligand residence time as an opportunity to impr...

    Call: OPUS 25 , Panel: NZ7

    Principal investigator: dr hab. Sabina Marta Podlewska

    Instytut Farmakologii PAN

  32. Impact of maternal monosaccharide diet on dams and offspring hippocampus development.

    Call: PRELUDIUM 22 , Panel: NZ1

    Principal investigator: Kacper Karol Witek

    Instytut Farmakologii PAN

  33. The effect of prolonged treatment with the new antipsychotics brexpiprazole and lumateperone on human liver function usi...

    Call: OPUS 26 , Panel: NZ4

    Principal investigator: dr Przemysław Jan Danek

    Instytut Farmakologii PAN

  34. Semaglutide and neurodevelopment: investigating risks arising from prenatal exposure to a widely popular drug for diabet...

    Call: OPUS 26 , Panel: NZ7

    Principal investigator: dr Agnieszka Wnuk

    Instytut Farmakologii PAN

  35. "Integrated Fixed-Dose Combination Drugs in Depression Therapy: A New Standard of Treatment and Mechanism of Action Stud...

    Call: OPUS 28 , Panel: NZ7

    Principal investigator: prof. Gabriel Piotr Nowak

    Instytut Farmakologii PAN

  36. NMR Spectroscopy as Molecular Language: A Deep Learning Approach to Bioactivity Prediction

    Call: PRELUDIUM 24 , Panel: NZ7

    Principal investigator: Arkadiusz Bogumił Leniak

    Instytut Farmakologii PAN

  37. EFFECTS OF ADENOSINE A2A RECEPTOR LIGANDS ON BEHAVIORAL EFFECTS OF ABUSED DRUG (COCAINE) AND NATURAL REWARD (FOOD) USING...

    Call: PRELUDIUM 2 , Panel: NZ7

    Principal investigator: Karolina Agnieszka Wydra

    Instytut Farmakologii PAN

  38. Plasticity of glutamatergic synapses on dopamine neurons: the mechanism of habit formation.

    Call: HARMONIA 3 , Panel: NZ4

    Principal investigator: dr hab. Jan Manuel Rodriguez-Parkitna

    Instytut Farmakologii PAN

  39. Effects of restraint stress on properties of neurons and synaptic transmission in hypothalamic paraventricular nucleus o...

    Call: PRELUDIUM 4 , Panel: NZ4

    Principal investigator: Magdalena Joanna Kusek

    Instytut Farmakologii PAN

  40. Examine the importance of intracellular pathways in the action of opioids in microglial cells in vitro

    Call: PRELUDIUM 4 , Panel: NZ3

    Principal investigator: Katarzyna Popiołek-Barczyk

    Instytut Farmakologii PAN

  41. Neural mechanisms underlying pathology of motivation.

    Call: SONATA BIS 2 , Panel: NZ3

    Principal investigator: dr Jan Manuel Rodriguez-Parkitna

    Instytut Farmakologii PAN

  42. The effect of enriched environment on the epigenetic mechanism in neurodevelopmental model of schizophrenia.

    Call: PRELUDIUM 4 , Panel: NZ4

    Principal investigator: dr Ewelina Bator

    Instytut Farmakologii PAN

  43. Antidepressats as substances that increase the activity of risperidone, an atypical antipsychotic drug in animal models

    Call: PRELUDIUM 5 , Panel: NZ7

    Principal investigator: Katarzyna Karolina Kamińska

    Instytut Farmakologii PAN

  44. Evaluation of histopathological changes in the rats tissues after acute and chronic administration of the compounds from...

    Call: PRELUDIUM 6 , Panel: NZ7

    Principal investigator: Edyta Dorota Możdżeń

    Instytut Farmakologii PAN

  45. Pessimism as cognitive biomarker of depression in animal model

    Call: OPUS 7 , Panel: NZ4

    Principal investigator: dr hab. Rafał Ryguła

    Instytut Farmakologii PAN

  46. Targeting peripheral cannabinoid receptors CB2 as a novel therapy to treat osteoarthritis

    Call: OPUS 7 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Maria Starowicz-Bubak

    Instytut Farmakologii PAN

  47. Identification of cytochrome P450 isoenzymes involved in the metabolism of levomepromazine in the human

    Call: OPUS 1 , Panel: NZ4

    Principal investigator: dr hab. Jacek Wójcikowski

    Instytut Farmakologii PAN

  48. Impact of selective modulators of estrogen and aryl hydrocarbon receptors on hypoxia/ischemia-induced neuronal cell dama...

    Call: PRELUDIUM 1 , Panel: NZ3

    Principal investigator: Joanna Rzemieniec

    Instytut Farmakologii PAN

  49. The influence of perinatal exposure to selective serotonin reuptake inhibitors on the structure and functions of mice do...

    Call: OPUS 14 , Panel: NZ4

    Principal investigator: prof. Grzegorz Władysław Hess

    Instytut Farmakologii PAN

  50. The role of selected metabotropic glutamate receptors in the mechanism of rapid antidepressant effect of RS-ketamine and...

    Call: OPUS 14 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Pałucha-Poniewiera

    Instytut Farmakologii PAN