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Keywords: targeted protein degradation

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10 projects found matching your search criteria:

1. Protein targeting to degradation: a new role of ABI1 protein phosphatase 2C in ethylene biosynthesis

Principal investigator: dr Agnieszka Ludwików

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Call: OPUS 8, Panel: NZ3
2. Human exosomes as natural carriers of protein kinase CK2 inhibitors and degraders in targeted anticancer therapy.

Principal investigator: dr hab. Patrycja Joanna Wińska

Politechnika Warszawska

Call: OPUS 28 (LAP), Panel: NZ5
3. The mechanisms of protein targeting to the endoplasmic reticulum channels during ER-associated degradation (ERAD)

Principal investigator: dr hab. Monika Agnieszka Słomińska-Wojewódzka

Uniwersytet Gdański, Wydział Biologii

Call: OPUS 10, Panel: NZ3
4. PROteolysis TArgeting Chimeras (PROTACs) intended to knock down excessive amyloidogenic proteins, human islet amyloid po…

Principal investigator: dr hab. Elżbieta Jankowska

Uniwersytet Gdański, Wydział Chemii

Call: OPUS 26, Panel: NZ7
5. Targeted Degradation of the MLL Complex in Leukemia: A PROTAC-Based Therapeutic Strategy

Principal investigator: dr Natalia Anna Skrzypczak

Fundacja Uniwersytetu im. Adama Mickiewicza

Call: SONATINA 9, Panel: ST5
6. Selective autophagy-mediated protein degradation as a potential therapeutic strategy for the treatment of inflammatory c…

Principal investigator: dr hab. Monika Emilia Marcinkowska

Uniwersytet Jagielloński

Call: OPUS 28, Panel: NZ7
7. Targeted degradation of Rab geranylgeranyl transferase as a new approach to investigate prenylation of Rab GTPases

Principal investigator: dr hab. Edyta Violetta Gendaszewska-Darmach

Politechnika Łódzka, Wydział Biotechnologii i Nauk o Żywności

Call: PRELUDIUM BIS 2, Panel: NZ1
8. A double whammy for the NF-κB signalling pathway: development of TAK1 and IKKβ degraders against inflammation-driven dis…

Principal investigator: dr hab. Anna Karolina Więckowska

Uniwersytet Jagielloński, Collegium Medicum

Call: OPUS 24 (LAP), Panel: NZ7
9. Canonical and non-canonical roles of DDK in oncogenesis: a cornerstone for the development of novel, potent anticancer t…

Principal investigator: dr Jan Marian Suski

Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

Call: SONATA BIS 14, Panel: NZ3
10. Small molecule modulators of the tumor necrosis factor alpha signaling pathway for the inhibition of inflammatory proces…

Principal investigator: prof. Tadeusz Holak

Uniwersytet Gdański

Call: OPUS 27, Panel: NZ7

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