Projects funded by the NCN


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81 projects found matching your search criteria :

  1. Identification of age-related traces of Amyotrophic Lateral Sclerosis as a basis for the search for novel disease modifi...

    Call: OPUS 29 , Panel: NZ5

    Principal investigator: dr Agnieszka Marta Krzyżosiak

    Sieć Badawcza ŁUKASIEWICZ - PORT Polski Ośrodek Rozwoju Technologii

  2. Identifying changes in Purkinje cell chromatin dynamics as novel drivers of neuronal vulnerability in spinocerebellar at...

    Call: OPUS 29 , Panel: NZ2

    Principal investigator: dr Paweł Michał Świtoński

    Instytut Chemii Bioorganicznej PAN

  3. Positioning the aryl hydrocarbon receptor (AhR) as a new target for pharmacotherapy of sporadic Alzheimer disease: verif...

    Call: OPUS 28 , Panel: NZ7

    Principal investigator: prof. Małgorzata Kajta

    Instytut Farmakologii PAN

  4. Molecular insights into NAD+ metabolism in Huntington's disease: role in pathophysiology and preclinical assessment of t...

    Call: OPUS 28 , Panel: NZ5

    Principal investigator: dr hab. Marta Urszula Tomczyk

    Gdański Uniwersytet Medyczny

  5. IgLON5 disease: NeuroInflammatory Tauopathy and Encephalopathy: the Model for Inflammation towards early treatment of Ne...

    Call: JPND Call 2024 , Panel: NZ4

    Principal investigator: dr Natalia Eleonora Małek-Chudzik

    Politechnika Wrocławska

  6. Breaking Down Defenses: The Impact of Periodontopathogen Porphyromonas gingivalis on Blood-Brain Barrier Functionality

    Call: PRELUDIUM 23 , Panel: NZ5

    Principal investigator: Kamila Justyna Drzazga

    Uniwersytet Jagielloński

  7. "I can see it in your eyes...": Visual Field Inhomogenities As an Early Marker of Neurodegeneration.

    Call: PRELUDIUM 23 , Panel: HS6

    Principal investigator: Julia Magdalena Papiernik-Kłodzińska

    Uniwersytet Jagielloński

  8. Assessment of the potential of new histidine hybrids and simulation of their metabolism as a potential therapy for neuro...

    Call: OPUS 27 , Panel: NZ7

    Principal investigator: prof. Paweł Bartosz Szymański

    Uniwersytet Medyczny w Łodzi

  9. Gut-brain-axis perspective on the impact of Cannabis flos on the blood-brain-barrier

    Call: PRELUDIUM 23 , Panel: NZ7

    Principal investigator: dr Małgorzata Maria Kołtun-Jasion

    Warszawski Uniwersytet Medyczny

  10. Nuclear protein quality control in neurodegeneration

    Call: SONATA 19 , Panel: NZ3

    Principal investigator: dr Lidia Wróbel

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

  11. Evaluation of P2X7 purinergic receptor as a trigger of brain metabolic abnormalities and neuronal degeneration in a mous...

    Call: SONATA BIS 13 , Panel: NZ4

    Principal investigator: dr Anna Wilkaniec

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  12. The role of DNA methylation and alternative splicing involvement in pathogenesisof the spinocerebellar ataxia type 8 (SC...

    Call: OPUS 25 , Panel: NZ4

    Principal investigator: dr hab. Anna Marzena Sułek

    Uczelnia Łazarskiego

  13. Multiomic characterization of neurogenerative processes in Zebrin-II positive and Zebrin-II negative Purkinje cells

    Call: PRELUDIUM 22 , Panel: NZ3

    Principal investigator: Grażyna Beata Jamróg

    Instytut Chemii Bioorganicznej PAN

  14. Activation of retrotransposons underlying neurodegenerative disease ALS related to mutations in FUS protein

    Call: PRELUDIUM 22 , Panel: NZ5

    Principal investigator: Patrycja Agnieszka Świergiel

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  15. Blood plasma microRNA profile as a basis for detecting Alzheimer's disease and dementia risk in pre-symptomatic individu...

    Call: OPUS 24 , Panel: NZ7

    Principal investigator: prof. Urszula Wojda

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  16. Study of the regenerative potential of Stem Cells from Human Exfoliated Deciduous teeth (SHED) in Alzheimer's disease

    Call: POLONEZ BIS 3 , Panel: NZ3

    Principal investigator: dr Leila Elyasi

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  17. Evaluation of immunomodulatory and neuroregenerative capacity of glial cell derived from human mesenchymal stem cells of...

    Call: PRELUDIUM BIS 4 , Panel: NZ4

    Principal investigator: dr hab. Joanna Beata Sypecka

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  18. Neuroprotective properties of β-cyclodextrin-1,2,4-triazole inclusion complexes

    Call: PRELUDIUM BIS 4 , Panel: NZ7

    Principal investigator: prof. Tomasz Sylwester Plech

    Uniwersytet Medyczny w Lublinie

  19. Effect of light pollution on visual system aging - research based on Drosophila melanogaster model

    Call: OPUS 24 , Panel: NZ3

    Principal investigator: dr Milena Anna Damulewicz

    Uniwersytet Jagielloński, Wydział Biologii

  20. The link between circadian clock, light pollution and Parkinson's disease development - research on Drosophila melanogas...

    Call: SONATA BIS 12 , Panel: NZ3

    Principal investigator: dr hab. Milena Anna Damulewicz

    Uniwersytet Jagielloński, Wydział Biologii

  21. Molecular Mechanisms of Dietary Intervention on Neurodegeneration

    Call: JPND Call 2022 , Panel: NZ2

    Principal investigator: dr hab. Maciej Figiel

    Instytut Chemii Bioorganicznej PAN

  22. Interlaminar astrocytes in primates – from molecular signature to functions in-vivo

    Call: OPUS 22 , Panel: NZ2

    Principal investigator: dr hab. Aleksandra Barbara Pękowska

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  23. Perinuclear AKAP6 signalosome as a new target for gene therapy in ischemic optic neuropathy

    Call: OPUS 22 , Panel: NZ4

    Principal investigator: dr hab. Tomasz Boczek

    Uniwersytet Medyczny w Łodzi, Wydział Nauk o Zdrowiu

  24. Elucidating neurodegenerative processes using direct profiling of selectively vulnerable neurons

    Call: SONATA 17 , Panel: NZ3

    Principal investigator: dr Paweł Michał Świtoński

    Instytut Chemii Bioorganicznej PAN

  25. Small-molecule inhibitors of protein aggregation and ER stress as a novel strategy against neurodegeneration in the cour...

    Call: PRELUDIUM BIS 3 , Panel: NZ5

    Principal investigator: prof. Ireneusz Jacek Majsterek

    Uniwersytet Medyczny w Łodzi

  26. Laser Emission of Thioflavin T and its analogues to uncover the early symptoms of neurodegenerative diseases.

    Call: SONATA 17 , Panel: ST4

    Principal investigator: dr Piotr Hańczyc

    Uniwersytet Warszawski, Wydział Fizyki

  27. Porphyromonas gingivalis as an etiologic factor in the development of neuroinflammation and neurodegeneration - studies ...

    Call: OPUS 22 , Panel: NZ6

    Principal investigator: prof. Magdalena Katarzyna Chadzińska

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  28. Searching for the mechanisms inducing improvement in motor function and prolonging the lifespan in amyotrophic lateral s...

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Damian Józef Flis

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

  29. Identification of novel disease modifiers in Huntington's disease: neuro-glia interactions in the patient-derived multid...

    Call: SONATA BIS 11 , Panel: NZ3

    Principal investigator: dr Agnieszka Marta Krzyżosiak

    Sieć Badawcza ŁUKASIEWICZ - PORT Polski Ośrodek Rozwoju Technologii

  30. Selective activation of non-nuclear Estrogen Receptor signaling with PaPE-1 as a novel therapeutic approach for sporadic...

    Call: OPUS 20 , Panel: NZ7

    Principal investigator: prof. Małgorzata Kajta

    Instytut Farmakologii PAN

  31. Molecular mechanism of the protective effect of swimming training on skeletal muscle atrophy and the course of amyotroph...

    Call: OPUS 20 , Panel: NZ7

    Principal investigator: prof. Wiesław Ziółkowski

    Gdański Uniwersytet Medyczny, Wydział Nauk o Zdrowiu z Instytutem Medycyny Morskiej i Tropikalnej

  32. New approach for neuronal regeneration and survival following ischemic stroke - gene therapy based on MEF2A repression u...

    Call: SONATA 16 , Panel: NZ4

    Principal investigator: dr Malwina Anna Lisek

    Uniwersytet Medyczny w Łodzi, Wydział Nauk o Zdrowiu

  33. Toxic RNA with expanded trinucleotide repeats: pathomechanism and therapeutic targets of neurological diseases

    Call: MAESTRO 12 , Panel: NZ3

    Principal investigator: prof. Krzysztof Sobczak

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  34. The role of the Fas/FasL pathway in neurodegeneration caused by herpes simplex type 1 (HSV-1) infection

    Call: OPUS 19 , Panel: NZ6

    Principal investigator: dr hab. Małgorzata Krzyżowska

    Wojskowy Instytut Higieny i Epidemiologii im. gen. Karola Kaczkowskiego

  35. Physical exercise as a natural mechanism inducing neuroregeneration. Search for the new protein markers and therapeutic ...

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Zofia Kuter-Nowak

    Instytut Farmakologii PAN

  36. Molecular mechanisms modulating the function of UCH-L1 deubiquitinase in human mitochondria

    Call: OPUS 18 , Panel: NZ3

    Principal investigator: prof. Agnieszka Małgorzata Chacińska

    Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

  37. Involvement of astrocytes in the neuroprotective mechanism evoked by enhancement of noradrenergic transmission in trasng...

    Call: PRELUDIUM 18 , Panel: NZ7

    Principal investigator: Justyna Beata Barut

    Instytut Farmakologii PAN

  38. Adeno-associated virus (AAV)-based gene therapy in the regeneration of optic nerve after ischemic stroke.

    Call: OPUS 17 , Panel: NZ4

    Principal investigator: dr hab. Tomasz Boczek

    Uniwersytet Medyczny w Łodzi, Wydział Nauk o Zdrowiu

  39. The effect of cytosolic adaptive responses associated with long-term mitochondrial stress on the Tau protein aggregation...

    Call: OPUS 17 , Panel: NZ3

    Principal investigator: dr Łukasz Samluk

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  40. miRNA as a potential biomarkers in motor neuron disease

    Call: PRELUDIUM 16 , Panel: NZ2

    Principal investigator: Filip Marek Tomczuk

    Instytut Psychiatrii i Neurologii

  41. The role of BET family proteins in microglia-dependent neurodegeneration; relevance to Alzheimer's disease

    Call: OPUS 16 , Panel: NZ4

    Principal investigator: dr hab. Grzegorz Arkadiusz Czapski

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  42. Multiscale and multiphase molecular dynamics of disordered proteins and proteinceous liquid droplets

    Call: OPUS 16 , Panel: NZ1

    Principal investigator: dr Mateusz Chwastyk

    Instytut Fizyki PAN

  43. Novel pharmacological strategies for the treatment of depression

    Call: OPUS 16 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Młyniec

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

  44. Role of arginase 2 in the function of the striatum and in the pathogenesis of Huntington's disease

    Call: SONATA BIS 8 , Panel: NZ1

    Principal investigator: dr Michał Tadeusz Węgrzynowicz

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  45. The role of glycogen synthase kinase 3 (GSK-3) in activation p53 and the TREM2 signaling pathway

    Call: PRELUDIUM 14 , Panel: NZ5

    Principal investigator: dr Barbara Małgorzata Łasut-Szyszka

    Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Oddział w Gliwicach

  46. The role of RAGE, receptor for advanced glycation end-products, in the progressive spinal motor neuron degeneration in f...

    Call: OPUS 13 , Panel: NZ4

    Principal investigator: prof. Joanna Alicja Wojtkiewicz

    Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Lekarski

  47. Evaluation of the influence of progressive noradrenergic neurodegeneration on dopaminergic system functioning in context...

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: dr Grzegorz Kreiner

    Instytut Farmakologii PAN

  48. Influence of copper and membrane-mimicking environment on the structure of the human Prion Protein N-terminal domain

    Call: PRELUDIUM 12 , Panel: ST5

    Principal investigator: Aleksandra Anna Hecel-Czaplicka

    Uniwersytet Wrocławski, Wydział Chemii

  49. Influence of metal ions on amyloidogenic properties of human cystatin C.

    Call: OPUS 11 , Panel: NZ1

    Principal investigator: dr hab. Aneta Szymańska

    Uniwersytet Gdański, Wydział Chemii

  50. Contribution of glutaminergic NMDA receptor to the mechanisms of nanosilver neurotoxicity in vivo

    Call: OPUS 11 , Panel: NZ7

    Principal investigator: prof. Lidia Marta Strużyńska

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN