Projects funded by the NCN

Frog skin derived cyclic peptide as a molecular scaffold to create a novel tool for combining visualization and inhibiti...

Call: PRELUDIUM 23 , Panel: ST5

Principal investigator: Aleksandra Dorota Helbik-Maciejewska

Uniwersytet Gdański

Small molecule modulators of the tumor necrosis factor alpha signaling pathway for the inhibition of inflammatory proces...

Call: OPUS 27 , Panel: NZ7

Principal investigator: prof. Tadeusz Holak

Uniwersytet Gdański

(Lipid-FLUX) Single-cell lipidomics by spectroscopy: Quantification of the lipid transport through the development of ne...

Call: OPUS 27 , Panel: ST4

Principal investigator: prof. Małgorzata Anna Barańska

Uniwersytet Jagielloński

Synthesis of novel hybrid nanomaterials based on fullerene scaffold for photodynamic therapy of cancer

Call: PRELUDIUM 23 , Panel: NZ7

Principal investigator: Dominik Jakub Dreszer

UNIWERSYTET ŚLĄSKI

Precision double strike against non-small cell lung cancer. Insights into multidirectional therapies and the landscape o...

Call: OPUS 27 , Panel: NZ5

Principal investigator: dr Katarzyna Anna Malarz

Politechnika Śląska

Evaluation of the relationship between doxorubicin resistance, epithelial-mesenchymal plasticity, and effects of selecte...

Call: PRELUDIUM 23 , Panel: NZ5

Principal investigator: Dominika Kunachowicz

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej

Controlling the covalent activity of a PD-L1 inhibitors with light

Call: PRELUDIUM 23 , Panel: NZ7

Principal investigator: Wiktor Jan Uzar

Uniwersytet Jagielloński

EGR1 Protein: A Key Factor in Cellular Homeostasis?

Call: PRELUDIUM 23 , Panel: NZ3

Principal investigator: Marta Leśniczak-Staszak

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Metastasis process regulation by inhibiting neutrophils NETosis through phytocannabinoids and the endocannabinoid system

Call: PRELUDIUM 23 , Panel: NZ1

Principal investigator: Izabela Marianna Krauze

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej

Proteomic predictors of metastasis in colorectal cancer – a validation study

Call: OPUS 27 , Panel: NZ5

Principal investigator: dr hab. Anna Wojakowska

Instytut Chemii Bioorganicznej PAN

Is organ-on-a-chip technology able to reduce animal sacrifice in studies on radiosensitizers?

Call: OPUS 27 , Panel: ST4

Principal investigator: prof. Janusz Adam Rak

Uniwersytet Gdański

The Prognostic Utility of Circulating Tumor Cells (CTCs) Derived from the Portal Vein in Operable Colorectal Cancer Pati...

Call: PRELUDIUM 23 , Panel: NZ5

Principal investigator: Claudia Dompé

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

The role of gratitude induced with a multi-component intervention in improving mental health outcomes of breast cancer p...

Call: SONATINA 8 , Panel: HS6

Principal investigator: dr Joanna Tomczyk

Uniwersytet im. Adama Mickiewicza w Poznaniu

Profiling of the phageome in relation to clinical outcomes in patients undergoing radical cystectomy and urinary diversi...

Call: SONATINA 8 , Panel: NZ6

Principal investigator: dr Katarzyna Anna Gembara

Wojewódzki Szpital Specjalistyczny we Wrocławiu. Ośrodek Badawczo-Rozwojowy

Cellular senescence as a new mechanism in development and progression of head and neck cancer

Call: OPUS 26 , Panel: NZ5

Principal investigator: prof. Michał Mateusz Masternak

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Defining the transcriptional and epigenetic state of tumor cells with increased plasticity and the epithelial-endothelia...

Call: OPUS 26 , Panel: NZ5

Principal investigator: dr hab. Agnieszka Kobielak

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

In search for DNA methylation aberrations associated with susceptibility to ovarian cancer

Call: OPUS 26 , Panel: NZ5

Principal investigator: dr Malwina Magdalena Suszyńska

Instytut Chemii Bioorganicznej PAN

To be or not to be modified: the role of single m6A sites of long noncoding RNAs in breast cancer

Call: SONATA 19 , Panel: NZ5

Principal investigator: dr Elżbieta Wanowska

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

β4-integrin is a guardian of nuclear integrity and chromatin accessibility limitingprostate cancer progression

Call: SONATA 19 , Panel: NZ2

Principal investigator: dr Tomasz Jacek Wenta

Uniwersytet Gdański, Wydział Biologii

The role of oxidative stress, inflammation, disorders of purine metabolism, urea cycle and angiogenesis at the molecular...

Call: SONATA 19 , Panel: NZ5

Principal investigator: dr Paulina Wigner-Jeziorska

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Organometallic (Fe, Ru, Ir, Os) phospho-inducers of drug-resistant cancer cells' ferroptosis

Call: OPUS 26 , Panel: ST4

Principal investigator: dr hab. Urszula Katarzyna Komarnicka

Uniwersytet Wrocławski, Wydział Chemii

Protease-induced neutrophilic networks in cancer development.

Call: SONATA 19 , Panel: NZ5

Principal investigator: dr Danuta Teresa Bryzek

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Targeting adenylate kinase 4 (AK4) as a new paradigm in the treatment of non-small cell lung cancer: discovery and evalu...

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr Magdalena Wujak

Uniwersytet Mikołaja Kopernika, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy

Exploring the influence of genomic features on mutational signatures across tumors

Call: OPUS 26 , Panel: NZ2

Principal investigator: dr Damian Michał Wójtowicz

Uniwersytet Warszawski, Wydział Matematyki, Informatyki i Mechaniki

Mucoadhesive nanospheres as an intravesical form of monomethyl auristatin E

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr hab. Katarzyna Jelonek

Centrum Materiałów Polimerowych i Węglowych PAN

Integrated multi-omics approach to accelerate anticancer drug discovery by targeting metabolic reprogramming in human co...

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr hab. Danuta Dudzik

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

Bacterial membrane carriers targeting tumor-associated microbes for advanced cancer therapy

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr Monika Kluzek

Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

Novel aspects of the mechanisms of vascular toxicity of tyrosine kinase inhibitors: studies on their proinflammatory act...

Call: OPUS 26 , Panel: NZ5

Principal investigator: dr Tomasz Krzysztof Prajsnar

Uniwersytet Jagielloński, Wydział Biologii

Design and characterisation of sealing materials of prosthetic obturator being additionally a cytostatic drug reservoir....

Call: OPUS 26 , Panel: ST8

Principal investigator: prof. Anna Trusek

Politechnika Wrocławska

Vascular dysfunction after breast cancer neoadjuvant chemotherapy.The significance of menopausal status and estrogens.

Call: SONATA 19 , Panel: NZ4

Principal investigator: dr Piotr Szczepaniak

Uniwersytet Jagielloński, Collegium Medicum

Increasing sensitivity to immunotherapy in lung cancer via immunostimulation and modulation of tumor microenvironment

Call: SONATA BIS 13 , Panel: NZ5

Principal investigator: dr Urszula Oleksiewicz

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Design and microfluidic synthesis of hybrid nanocarriers stabilized by novel sugar surfactants as a potential anticancer...

Call: SONATA BIS 13 , Panel: ST4

Principal investigator: dr hab. Urszula Jolanta Bazylińska

Politechnika Wrocławska

How is meiotic TEX12 re-activated in cancer and can we exploit this in the clinic?

Call: SONATA BIS 13 , Panel: NZ3

Principal investigator: dr Urszula Łucja Mcclurg

Instytut Biologii Medycznej PAN

Advanced statistical and deep learning models to predict cancer risk and support treatment decisions

Call: SONATA BIS 13 , Panel: NZ2

Principal investigator: dr Michał Marczyk

Politechnika Śląska, Wydział Automatyki, Elektroniki i Informatyki

XAICancer: Explainable Artificial Intelligence for Cancer Imaging

Call: SONATA BIS 13 , Panel: ST6

Principal investigator: dr Neo Christopher Chung

Uniwersytet Warszawski, Wydział Matematyki, Informatyki i Mechaniki

Extensive analysis of the immunological profile of pediatric patients with acute lymphoblastic leukemia in order to iden...

Call: PRELUDIUM 22 , Panel: NZ5

Principal investigator: Anna Krętowska-Grunwald

Uniwersytet Medyczny w Białymstoku

Development of novel bifunctional ceramic coatings with osteoinductive and anti-oncogenic properties on metallic implant...

Call: PRELUDIUM 22 , Panel: ST5

Principal investigator: Balbina Karina Makurat-Kasprolewicz

Politechnika Gdańska

The mechanism of competition of mutant p53 gain-of-function and major oncogene CMYC in gastric cancer.

Call: PRELUDIUM 22 , Panel: NZ5

Principal investigator: Marcin Mikołaj Grochowski

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Novel receptor materials for the construction of a bioelectronic nose for the rapid and efficient detection of lung canc...

Call: OPUS 25 , Panel: ST5

Principal investigator: prof. Wojciech Kamysz

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

Persistent luminescence thermometry of nano-phosphors and their biomedical potential

Call: OPUS 25 , Panel: ST5

Principal investigator: dr Justyna Anna Zeler

Uniwersytet Wrocławski, Wydział Chemii

Development of dual immuno-oligo- biosensors for monitoring and controlling of the metastatic colorectal cancer and inve...

Call: OPUS 25 , Panel: ST4

Principal investigator: dr hab. Magdalena Stobiecka

Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Instytut Biologii

Anticancer potential of TMPyP4 porphyrin in breast cancer photodynamic therapy and evaluation of the treatment safety

Call: OPUS 25 , Panel: NZ7

Principal investigator: prof. Błażej Rubiś

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Investigating mechanisms regulating ALCAM alternative splicing and susceptibility of this molecule to cleavage by shedda...

Call: OPUS 25 , Panel: NZ2

Principal investigator: dr Marta Karolina Wagner

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Multifunctional emulsion-based transporters for personalised cancer treatment

Call: OPUS 25 , Panel: ST8

Principal investigator: prof. Ewa Dłuska

Politechnika Warszawska, Wydział Inżynierii Chemicznej i Procesowej

Predictive Potential of Circulating MicroRNA Biomarkers in Patients with High Familial or Genetic Risk of Cancer

Call: OPUS 25 , Panel: NZ5

Principal investigator: prof. Wojciech Fendler

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Quantitation of metabolic turnover in single cancer cells by infrared microscopy

Call: OPUS 25 , Panel: NZ1

Principal investigator: dr Luca Quaroni

Uniwersytet Jagielloński, Wydział Chemii

INVADOPODIA IN AXL-DRIVEN CANCER INVASION AND DRUG RESISTANCE

Call: OPUS 25 , Panel: NZ3

Principal investigator: dr Daria Paulina Zdżalik-Bielecka

Uniwersytet Warszawski, Wydział Biologii

Targeting Energy Metabolism for Precision Cancer Therapy: Novel Inhibitors of LDH-A and PDK1 as Potential Strategies to ...

Call: PRELUDIUM 22 , Panel: NZ7

Principal investigator: Marika Anna Frańczak

Gdański Uniwersytet Medyczny, Wydział Lekarski

Chiral hybrids of quinones and quinols with double anticancer and antimicrobial activity against drug-resistant pathogen...

Call: OPUS 25 , Panel: NZ7

Principal investigator: prof. Ryszard Józef Ostaszewski

Instytut Chemii Organicznej Polska Akademia Nauk

Investigating the anti-cancerous effect of antioxidant extract from spent coffee grounds on the functioning of normal an...

Call: PRELUDIUM 22 , Panel: NZ5

Principal investigator: Adrianna Maria Piasek

Politechnika Warszawska, Wydział Chemiczny