Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Functional motif-targeted RNA structure modeling

2024/53/B/ST6/02789

Keywords:

RNA structure computational modeling of nucleic acid structure analysis of structure motifs motif-centric model evaluation editing and refinement of the structure optimization algorithms artificial intelligence machine learning multimodality

Descriptors:

  • ST6_13:
  • ST6_12:

Panel:

ST6 - Computer science and informatics: informatics and information systems, computer science, scientific computing, intelligent systems

Host institution :

Politechnika Poznańska

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Marta Xymena Szachniuk 

Number of co-investigators in the project: 6

Call: OPUS 27 - announced on 2024-03-21

Amount awarded: 1 238 910 PLN

Project start date (Y-m-d): 2025-01-02

Project end date (Y-m-d): 2029-01-01

Project duration:: 48 months (the same as in the proposal)

Project status: Pending project

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (5)
  1. A retroelement-derived mammalian ARC protein exhibits selective RNA recognition and nucleic acid chaperone functions
    Authors:
    Julita Gumna-Mikina, Angelika Andrzejewska-Romanowska, Maciej Antczak, Ewa Tykwinska, Marta Szachniuk, Katarzyna Pachulska-Wieczorek
    Academic press:
    Nucleic Acids Research (rok: 2026, tom: 54, strony: gkag207), Wydawca: Oxford University Press
    Status:
    Published
    DOI:
    10.1093/nar/gkag207 - link to the publication
  2. FRET-guided selection of RNA 3D structures
    Authors:
    Mirko Weber, Felix Erichson, Maciej Antczak, Vanessa Schumann, Josephine Meitzner, Tomasz Zok, Fabio D. Steffen, Marta Szachniuk, Richard Borner
    Academic press:
    Nucleic Acids Research (rok: 2026, tom: 54, strony: gkag147), Wydawca: Oxford University Press
    Status:
    Published
    DOI:
    10.1093/nar/gkag147 - link to the publication
  3. RNAsolo 2.0: multimodal database to study RNAs, their structural families and intermolecular interfaces
    Authors:
    Bartosz Adamczyk, Pawel Boinski, Marta Szachniuk, Maciej Antczak
    Academic press:
    Journal of Molecular Biology (rok: 2026, tom: 438, strony: 169570), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jmb.2025.169570 - link to the publication
  4. Graph Neural Network and Diffusion Model for modeling RNA interatomic interactions
    Authors:
    Marek Justyna, Craig L Zirbel, Maciej Antczak, Marta Szachniuk
    Academic press:
    Bioinformatics (rok: 2025, tom: 41, strony: btaf515), Wydawca: Oxford University Press
    Status:
    Published
    DOI:
    10.1093/bioinformatics/btaf515 - link to the publication
  5. Detecting polynucleotide motifs: Pentads, hexads, and beyond
    Authors:
    Michal Zurkowski, Maja Marusic, Dorota Gudanis-Sobocinska, Marta Szachniuk
    Academic press:
    PLoS Computational Biology (rok: 2025, tom: 21, strony: e1013633), Wydawca: Public Library of Science
    Status:
    Published
    DOI:
    10.1371/journal.pcbi.1013633 - link to the publication

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