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Development of three-photon emitting radiotracers for positronium imaging

2021/43/B/ST2/02150

Keywords

Descriptors

  • ST2_003: Fizyka jądrowa
  • ST2_020: Inne zagadnienia pokrewne
  • NZ1_003: Biofizyka

Panel

ST2 – Fundamental constituents of matter: particle, nuclear, plasma, atomic, molecular, gas and optical physics

Host institution

Uniwersytet Jagielloński, Wydział Fizyki, Astronomii i Informatyki Stosowanej

Voivodeship: małopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

prof. Paweł Artur Moskal

Number of co-investigators in the project: 7

Call

OPUS 22 – announced on 2021-09-15

Amount awarded
2 534 130 PLN
Project start date
2022-07-21
Project end date
2027-04-20
Project duration
57 months (the same as in the proposal)
Project status
Pending project

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (17)

  1. 3D melanoma spheroid model for the development of positronium biomarkers

    Authors:
    H. Karimi, P. Moskal, A. Żak, E. Ł. Stępień
    Academic press:
    Scientific Reports (year: 2023, volume: 13, pages: 7648), Publisher: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s41598-023-34571-4 – link to the publication

  2. Colloquium: Positronium physics and biomedical applications

    Authors:
    S.D. Bass, S. Mariazzi, P. Moskal, E. Stępień
    Academic press:
    Reviews of Modern Physics (year: 2023, volume: 90, pages: 21002), Publisher: American Physical Society
    Status:
    Published
    DOI:
    10.1103/RevModPhys.95.021002 – link to the publication

  3. Efficiency determination of J-PET: first plastic scintillators-based PET scanner

    Authors:
    S. Sharma, J. Baran, N. Chug, C. Curceanu, E. Czerwiński, M. Dadgar, K. Dulski, K. Eliyan, A. Gajos, N. Gupta‑Sharma, B. C. Hiesmayr, K. Kacprzak, Ł. Kapłon, K. Klimaszewski, P. Konieczka, G. Korcyl, T. Kozik, W. Krzemień, D. Kumar, Sz. Niedźwiecki, D. Panek, S. Parzych, E. Perez del Rio, L. Raczyński, Shivani Choudhary, R. Y. Shopa, M. Skurzok, E. Ł. Stępień, F. Tayefi, K. Tayefi, W. Wiślicki and P. Moskal
    Academic press:
    EJNMMI Physics (year: 2023, volume: 10, pages: 28), Publisher: Springer
    Status:
    Published
    DOI:
    10.1186/s40658-023-00546-7 – link to the publication

  4. Transformation of PET raw data into images for event classification using convolutional neural networks

    Authors:
    Paweł Konieczka, Lech Raczyński, Wojciech Wiślicki, Oleksandr Fedoruk, Konrad Klimaszewski, Przemysław Kopka, Wojciech Krzemień, Roman Y. Shopa, Jakub Baran, Aurelien Coussat, Neha Chug, Catalina Curceanu, Eryk Czerwiński, Meysam Dadgar, Kamil Dulski, Aleksander Gajos, Beatrix C. Hiesmayr, Krzysztof Kacprzak, Łukasz Kapłon, Grzegorz Korcyl, Tomasz Kozik, Deepak Kumar, Szymon Niedźwiecki, Szymon Parzych, Elena Perez del Rio, Sushil Sharma, Shivani Shivani, Magdalena Skurzok, Ewa Łucja Stepień, Faranak Tayefi and Paweł Moskal
    Academic press:
    Mathematical Biosciences and Engineering (year: 2023, volume: 20, pages: 14938–14958), Publisher: AIMS Press
    Status:
    Published
    DOI:
    10.3934/mbe.2023669 – link to the publication

  5. Comparative studies of plastic scintillator strips with high technical attenuation length for the total-body J-PET scanner

    Authors:
    Ł. Kapłon, J. Baran, N. Chug, A. Coussat, C. Curceanu, E. Czerwiński, M. Dadgar, K. Dulski, J. Gajewski, A. Gajos, B. Hiesmayr, E. Kavya Valsan, K. Klimaszewski, G. Korcyl, T. Kozik, W. Krzemień, D. Kumar, G. Moskal, S. Niedźwiecki, D. Panek, S. Parzych, E. Pérez del Rio, L. Raczyński, A. Ruciński, S. Sharma, S. Shivani, R. Shopa, M. Silarski, M. Skurzok, E. Stępień, F. Tayefi Ardebili, K. Tayefi Ardebili, W. Wiślicki, P. Moskal
    Academic press:
    Nuclear Instruments and Methods A (year: 2023, volume: 1051, pages: 168186), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.nima.2023.168186 – link to the publication

  6. Multi-photon time-of-flight MLEM application for the positronium imaging in J-PET

    Authors:
    R. Shopa, K. Dulski
    Academic press:
    Bio-Algorithms and Med-Systems (year: 2022, volume: 19, pages: 135-143), Publisher: Index Copernicus International
    Status:
    Published
    DOI:
    10.2478/bioal-2022-0082 – link to the publication

  7. Positronium image of the human brain in vivo

    Authors:
    P. Moskal, J. Baran, S. Bass, J. Choiński, N. Chug, C. Curceanu, E. Czerwiński, M. Dadgar, M. Das, K. Dulski, K.V. Eliyan, K. Fronczewska, A. Gajos, K. Kacprzak, M. Kajetanowicz, T. Kaplanoglu, Ł. Kapłon, K. Klimaszewski, M. Kobylecka, G. Korcyl, T. Kozik, W. Krzemień, K. Kubat, D. Kumar, J. Kunikowska, J. Mączewska, W. Migdał, G. Moskal, W. Mryka, S. Niedźwiecki, S. Parzych, E. Perez del Rio, L. Raczyński, S. Sharma, Shivani, R.Y. Shopa, M. Silarski, M. Skurzok, F. Tayefi, K. Tayefi, P. Tanty, W. Wiślicki, L. Królicki, E. Ł. Stępień
    Academic press:
    Science Advances (year: 2024, volume: 10, pages: eadp2840), Publisher: American Association for the Advancement of Science
    Status:
    Published
    DOI:
    10.1126/sciadv.adp2840 – link to the publication

  8. Perspectives on translation of positronium imaging into clinics

    Authors:
    P. Moskal, E. Stępień
    Academic press:
    Frontiers in Physics (year: 2022, volume: 10, pages: 969806), Publisher: Frontiers
    Status:
    Published
    DOI:
    10.3389/fphy.2022.969806 – link to the publication

  9. A vision to increase the availability of PET diagnostics in low- and medium-income countries by combining a low-cost modular J-PET tomograph with the 44Ti/44Sc generator

    Authors:
    P. Moskal, E. Stępień, A. Khreptak
    Academic press:
    Bio-Algorithms and Med-Systems (year: 2024, volume: 20, pages: 55), Publisher: Index Copernicus International
    Status:
    Published
    DOI:
    10.5604/01.3001.0054.9273 – link to the publication

  10. TOF MLEM Adaptation for the Total-Body J-PET With a Realistic Analytical System Response Matrix

    Authors:
    R.Y. Shopa, J. Baran, K. Klimaszewski, W. Krzemień, L. Raczyński, W. Wiślicki, K. Brzeziński, N. Chug, A. Coussat, C. Curceanu, E. Czerwiński, M. Dadgar, K. Dulski, J. Gajewski, A. Gajos, B.C. Hiesmayr, E. Kavya Valsan, G. Korcyl, T. Kozik, D. Kumar, Ł. Kapłon, G. Moskal, S. Niedźwiecki, D. Panek, S. Parzych, E. Perez del Rio, A. Ruciński, S. Sharma, Shivani, M. Silarski, M. Skurzok, E. Stępień, F. Tayefi Ardebili, K. Tayefi Ardebili, P. Moskal
    Academic press:
    IEEE Transactions on Radiation and Plasma Medical Sciences (year: 2023, volume: 7, pages: 509 - 520), Publisher: IEEE
    Status:
    Published
    DOI:
    10.1109/TRPMS.2023.3243735 – link to the publication

  11. Evaluation of Modular J-PET sensitivity

    Authors:
    Faranak Tayefi Ardebili, Szymon Niedźwiecki, Paweł Moskal
    Academic press:
    Bio-Algorithms and Med-Systems (year: 2023, volume: 19, pages: 132-138), Publisher: Index Copernicus Iternational
    Status:
    Published
    DOI:
    10.5604/01.3001.0054.1973 – link to the publication

  12. Development of correction techniques for a J-PET scanner

    Authors:
    M. Das, R. Bayerlein, S. Sharma, S. Parzych, S. Niedźwiecki, R. Badawi, E. Yitayew Beyene, N. Chug, C. Curceanu, E. Czerwiński, K. Valsan Eliyan, B. Głowa, A. Hubalewska-Dydejczyk, K. Kacprzak, T. Kaplanoglu, K. Kasperska, G. Korcyl, A. Khreptak, K. Kubat, D. Kumar, E. Lisowski, F. Lisowski, J. Mędrala-Sowa, S. Moyo, W. Mryka, M. Opalińska, P. Pandey, M. Rädler, M. Skurzok, A. Sowa-Staszczak, B. A. Spencer, P. Tanty, K. Tayefi Ardebili, A. Kunimmal Venadan, E. Stępień, P. Moskal
    Academic press:
    Bio-Algorithms and Med-Systems (year: 2024, volume: 20, pages: 101), Publisher: Index Copernicus International
    Status:
    Published
    DOI:
    10.5604/01.3001.0054.9362 – link to the publication

  13. Assessing the Spatial Resolution of the Modular J-PET Scanner using the Maximum-Likelihood Expectation-Maximization (MLEM) algorithm

    Authors:
    F. Tayefi Ardebili, P. Moskal
    Academic press:
    Bio-Algorithms and Med-Systems (year: 2024, volume: 20, pages: 1), Publisher: Index Copernicus International
    Status:
    Published
    DOI:
    10.5604/01.3001.0054.8095 – link to the publication

  14. Calculational Cross-Sections of (p, x) Reactions on the 12C, 14N and 16O for 10,11C Production

    Authors:
    N. Sakhno, W. Mryka, O. Gorbachenko, I. Kadenko, E. Stępień, P. Moskal
    Academic press:
    Acta Physica Polonica A (year: 2024, volume: 146, pages: 731), Publisher: Inst
    Status:
    Published
    DOI:
    10.12693/APhysPolA.146.731 – link to the publication

  15. Calibration of PALS System with CRM Materials for Biomedical Studies

    Authors:
    K. Kubat, Ł. Kapłon, P. Moskal, E. Stępień
    Academic press:
    Bio-Algorithms and Med-Systems (year: 2024, volume: 20, pages: 35), Publisher: Index Copernicus International
    Status:
    Published
    DOI:
    10.5604/01.3001.0054.9091 – link to the publication

  16. Exploration of simultaneous dual-isotope imaging with a multiphoton modular J-PET scanner

    Authors:
    Ermias Y. Beyene, Manish Das, Martyna Durak-Kozica, Grzegorz Korcyl, Wiktor Mryka, Szymon Niedźwiecki, Szymon Parzych, Keyvan Tayefi, Rafał Walczak, Kamil Wawrowicz, Ewa Stepien, Pawel Moskal
    Academic press:
    Bio-Algorithms and Med-Systems (year: 2023, volume: 19, pages: 101-108), Publisher: Index Copernicus International
    Status:
    Published
    DOI:
    10.5604/01.3001.0054.1940 – link to the publication

  17. Estimating the efficiency and purity for detecting annihilation and prompt photons for positronium imaging with J-PET using toy Monte Carlo simulation

    Authors:
    Manish Das, Wiktor Mryka, Ermias Y. Beyene, Szymon Parzych, Ewa Stępień and Paweł Moskal
    Academic press:
    Bio-Algorithms and Med-Systems (year: 2023, volume: 19, pages: 87-95), Publisher: Index Copernicus International
    Status:
    Published
    DOI:
    10.5604/01.3001.0054.1938 – link to the publication

Articles in post-conference publications (2)

  1. Developing a phantom for the positronium imaging evaluation.

    Authors:
    G. Łapkiewicz, S. Niedźwiecki, P. Moskal
    Conference:
    4th Jagiellonian Symposium on Advances in Particle Physics and Medicine (year: 2022, volume: 4th Jagiellonian Symposium on Advances in Particle Physics and Medicine, pages: 4-A4), Publisher: Polish Academy of Sciences
    Date:
    conference 10-15 July 2022
    Status:
    Published
    DOI:
    10.5506/APhysPolBSupp.15.4-A4 – link to the publication

  2. Estimation of 511 keV Gamma Scatter Fraction in WLS Layer in Total-Body J-PET; A Simulation Study

    Authors:
    K. Tayefi Ardebili, S. Niedzwiecki, P. Moskal
    Conference:
    4th Jagiellonian Symposium on Advances in Particle Physics and Medicine (year: 2022, volume: 4th Jagiellonian Symposium on Advances in Particle Physics and Medicine, pages: 4-A7), Publisher: Polish Academy of Sciences
    Date:
    conference 10-15 July 2022
    Status:
    Published
    DOI:
    10.5506/APhysPolBSupp.15.4-A7 – link to the publication

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Graphic design and implementation: Jakub Piotrowski