Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Separation of enantiomeric mixtures of pharmaceutically active substances using hybrid processes of achiral and chiral chromatography and achiral crystallzation

2021/41/B/ST8/00631

Keywords:

chromatography crystallization enantiomers separation SMB chromatography

Descriptors:

  • ST8_001:

Panel:

ST8 - Production and processes engineering: modelling, product design, process design and control, construction methods and engineering, power units and systems

Host institution :

Politechnika Rzeszowska im. Ignacego Łukasiewicza, Wydział Chemiczny

woj. podkarpackie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Dorota Antos 

Number of co-investigators in the project: 8

Call: OPUS 21 - announced on 2021-03-15

Amount awarded: 1 529 600 PLN

Project start date (Y-m-d): 2022-01-12

Project end date (Y-m-d): 2025-07-11

Project duration:: 42 months (the same as in the proposal)

Project status: Project completed

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (2)
  1. Separation of nonracemic mixtures of enantiomers by achiral simulated moving bed chromatography
    Authors:
    W. K. Marek, J. W. Lee, A. Seidel-Morgenstern, D. Antos
    Academic press:
    Separation and Purification Technology (rok: 2025, tom: 361, strony: 131497), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.seppur.2025.131497 - link to the publication
  2. Altering the mobile phase composition to enhance self-disproportionation of enantiomers in achiral chromatography
    Authors:
    Patrycja Mruc, Maksymilian Olbrycht, Markiian Korbetskyy, Dorota Antos
    Academic press:
    Journal of Chromatography A (rok: 2024, tom: 1715, strony: 464603), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.chroma.2023.464603 - link to the publication