Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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15-oxo-eicosatetraenoic acid (15-oxo-ETE) as a potential diagnostic biomarker of aspirin-exacerbated respiratory disease.

2021/41/B/NZ5/00305

Keywords:

aspirin-exacerbated respiratory disease 15-oxo-ETE in vitro diagnostic tests

Descriptors:

  • NZ5_005:

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Uniwersytet Jagielloński, Collegium Medicum

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Lucyna Maria Mastalerz 

Number of co-investigators in the project: 8

Call: OPUS 21 - announced on 2021-03-15

Amount awarded: 818 660 PLN

Project start date (Y-m-d): 2022-01-13

Project end date (Y-m-d): 2024-10-12

Project duration:: 33 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (2)
  1. Aspirin hypersensitivity diagnostic index (AHDI): In vitro test for diagnosing of N-ERD based on urinary 15-oxo-ETE and LTE4 excretion
    Authors:
    Mastalerz L., Trąd G., Szatkowski P., Ćmiel A, Gielicz A, Kacorzyk R, Plutecka H, Szaleniec J, Gawlewicz-Mroczka A, Jakieła B, Sanak M.
    Academic press:
    Allergy (rok: 2024, tom: online, strony: online), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1111/all.16281 - link to the publication
  2. Metabolomic endophenotypes based on oxo-eicosatetraenoic acids in patients with aspirin-exacerbated respiratory disease
    Authors:
    Szatkowski, P., Stępień, A., Ćmiel, A., Kacorzyk, R., Trąd-Wójcik, G., Gacek, E., Mastalerz, L.
    Academic press:
    Journal of Allergy and Clinica Immunology (rok: 2025, tom: 156(3), strony: 616–626), Wydawca: Elsevier Inc.
    Status:
    Published
    DOI:
    10.1016/j.jaci.2025.04.036 - link to the publication