Projects funded by the NCN
Role of SAT1 glutamine transporter in the neurotransmission balance: implications for anxiety-related disorders.
2020/39/B/NZ5/01962
Keywords:
glutamine SAT1 transporter GABA anxiety BDNF
Descriptors:
- NZ5_003:
- NZ3_006:
- NZ4_007:
Panel:
NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)
Host institution :
Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk
woj. mazowieckie
Principal investigator (from the host institution):
Number of co-investigators in the project: 6
Call: OPUS 20 - announced on 2020-09-15
Amount awarded: 1 747 960 PLN
Project start date (Y-m-d): 2021-07-16
Project end date (Y-m-d): 2026-07-15
Project duration:: 60 months (the same as in the proposal)
Project status: Pending project
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Articles in post-conference publications (3)
- Impact of SAT1 transporter decline on chronic social stress status in mice.Authors:Zuzanna Sulej, Mariusz Popek, Marta Obara-Michlewska, Karolina Orzeł-Gajowik, Magdalena ZielińskaConference:Folia Neuropathologica 62/4 (rok: 2024, tom: XVI International Symposium Molecular basis of pathology and therapy in neurological disorders, strony: 506), Wydawca: Mossakowski Medical Research Institute, Polish Academy of SciencesData:konferencja 17-18 October 2024Status:PublishedDOI:10.5114/fn.2024.147358 - link to the publication
- The absence of the glutamine transporter SNAT1 affects neuronal oestrogen receptor β signalling in female mice with chronic stress syndromeAuthors:Daniel Kalinowski, Marta Obara-Michlewska, Magdalena ZielińskaConference:Folia Neuropathologica 62/4 (rok: 2024, tom: XVI International Symposium Molecular basis of pathology and therapy in neurological disorders, strony: 498), Wydawca: Mossakowski Medical Research Institute, Polish Academy of SciencesData:konferencja 17-18 October 2024Status:PublishedDOI:10.5114/fn.2024.147358 - link to the publication
- Glutamine transporter SAT1 deficiency promotes anxiety-like behavior in mice: Element in neurotransmiter imbalance hypothesis?Authors:Mariusz Popek, Karolina Orzeł‐Gajowik, Zuzanna Sulej, Marta Obara‐Michlewska, Kamila Szumska, Magdalena ZielińskaConference:Journal of Neurochemistry Volume166, Issue S2 Special Issue: ISN‐ESN 2023 Meeting (rok: 2023, tom: ISN‐ESN 2023 Meeting Porto, Portugal, strony: 81 B 7-10 str. 119‐120), Wydawca: WileyData:konferencja 8‐11 August 2023Status:Published