Projects funded by the NCN

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The influence of menaquinone-7 on leukocyte and CD4+ transcriptomes in ulcerative colitis: a randomized controlled trial

2020/39/D/NZ5/02720

Keywords:

inflammatory bowel disease transcriptome expression

Descriptors:

  • NZ5_007:
  • NZ2_002:

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Jan Krzysztof Nowak 

Number of co-investigators in the project: 7

Call: SONATA 16 - announced on 2020-09-15

Amount awarded: 758 208 PLN

Project start date (Y-m-d): 2021-06-11

Project end date (Y-m-d): 2025-06-10

Project duration:: 48 months (the same as in the proposal)

Project status: Project completed

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  1. Current and emerging biomarkers for ulcerative colitis
    Authors:
    Nowak JK, Kalla R, Satsangi J
    Academic press:
    Expert Review of Molecular Diagnostics (rok: 2023, tom: 23, strony: 1107-1119), Wydawca: Taylor & Francis
    Status:
    Published
    DOI:
    10.1080/14737159.2023.2279611 - link to the publication
  2. Study designs in medical research and their key characteristics
    Authors:
    Jan K. Nowak, Jarosław Walkowiak
    Academic press:
    Journal of Medical Science (rok: 2024, tom: 92, strony: 305-315), Wydawca: Uniwersytet Medyczny w Poznaniu
    Status:
    Published
    DOI:
    10.20883/medical.e928 - link to the publication
  3. Defining Interactions Between the Genome, Epigenome, and the Environment in Inflammatory Bowel Disease: Progress and Prospects
    Authors:
    Alexandra J. Noble, Jan K. Nowak, Alex T. Adams, Holm H. Uhlig, Jack Satsangi
    Academic press:
    Gastroenterology (rok: 2023, tom: 165, strony: 44-60.e2), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1053/j.gastro.2023.03.238 - link to the publication
  4. Altered DNA methylation within DNMT3A, AHRR, LTA/TNF loci mediates the effect of smoking on inflammatory bowel disease
    Authors:
    Han Zhang, Rahul Kalla, Jie Chen, Jianhui Zhao, Xuan Zhou, Alex Adams, Alexandra Noble, Nicholas T. Ventham, Judith Wellens, Gwo-Tzer Ho, Malcolm G. Dunlop, Jan Krzysztof Nowak, Yuan Ding, Zhanju Liu, Jack Satsangi, Evropi Theodoratou, Xue Li
    Academic press:
    Nature Communications (rok: 2024, tom: 15, strony: 595), Wydawca: Nature Portfolio
    Status:
    Published
    DOI:
    10.1038/s41467-024-44841-y - link to the publication

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