The overlap between cannabinoid and nociceptin signaling and its role in intestinal inflammation

2020/37/N/NZ5/01478

Keywords

Descriptors

  • NZ5_003: Patogeneza chorób człowieka
  • NZ5_007: Leczenie chorób człowieka

Panel

NZ5 – Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Voivodeship: łódzkie

Other projects carried out by the institution »

Principal investigator (from the host institution)

Adam Fabisiak

Number of co-investigators in the project: 3

Call

PRELUDIUM 19 – announced on 2020-03-16

Amount awarded
209 932 PLN
Project start date
2021-02-11
Project end date
2024-02-10
Project duration
36 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (3)

  1. Modulation of CB1 and CB2 receptors and endocannabinoid activity in inflammatory bowel diseases

    Authors:
    Maria Wołyniak, Marcin Włodarczyk, Fabiana Piscitelli, Roberta Verde, Vincenzo Di Marzo, Anna Mokrowiecka, Ewa Małecka-Wojciesko, Adam Fabisiak
    Academic press:
    Journal of Physiology and Pharmacology (year: 2024, volume: 75, pages: 547-555), Publisher: Polskie Towarzystwo Fizjologiczne
    Status:
    Published
    DOI:
    10.26402/jpp.2024.5.08 – link to the publication
  2. A Crosstalk between the Cannabinoid Receptors and Nociceptin Receptors in Colitis - Clinical Implications

    Authors:
    Maria Wołyniak, Ewa Małecka-Wojciesko, Marta Zielińska, Adam Fabisiak
    Academic press:
    Journal of Clinical Medicine (year: 2022, volume: 11, pages: 6675), Publisher: MDPI, Basel, Switzerland
    Status:
    Published
    DOI:
    10.3390/jcm11226675 – link to the publication
  3. Combined CB1 antagonist AM6545 and NOP agonist SCH221510 worsen DSS-induced colitis in mice

    Authors:
    Adam Fabisiak, Maria Wołyniak, Fabiana Piscitelli, Roberta Verde, Vincenzo Di Marzo, Marta Zielińska, Weronika Machelak, Ewa Małecka-Wojciesko.
    Status:
    Accepted for publication

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