Lanthanide binding oligonucleotides (LBOs) as paramagnetic tags for NMR spectros

Lanthanide binding oligonucleotides (LBOs) as paramagnetic tags for NMR spectroscopy of nucleic acids

2020/37/B/ST4/03182

Keywords

Descriptors

ST4_002: Metody spektroskopowe i spektrometryczne
ST4_003: Struktura i architektura molekularna
ST4_009: Chemia biologiczna

Panel

ST4 – Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution

Instytut Chemii Bioorganicznej PAN

Voivodeship: wielkopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Witold Jacek Andrałojć

Number of co-investigators in the project: 5

Call

OPUS 19 – announced on 2020-03-16

Amount awarded: 1 240 800 PLN
Project start date: 2021-04-01
Project end date: 2027-03-31
Project duration: 72 months (the same as in the proposal)
Project status: Pending project

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (3)

Experimental and computational investigations of RNA duplexes containing N7-regioisomers of adenosine and LNA-adenosine

Authors:
I. Yildirim, W. Andrałojć, A. Taghavi, D. Baranowski, Z. Gdaniec, R. Kierzek, E. Kierzek

Academic press:
Nucleic Acids Ressearch (year: 2025, volume: 53, pages: gkae1222), Publisher: Oxford University Press

Status:
Published

DOI:
10.1093/nar/gkae1222 – link to the publication
Solution Structure of a Lanthanide-binding DNA Aptamer Determined Using High Quality pseudocontact shift restraints

Authors:
Witold Andrałojć, Julia Wieruszewska, Karol Pasternak, Zofia Gdaniec

Academic press:
Chemistry – A European Journal (year: 2022, volume: 28, pages: e202202114), Publisher: WILEY-V C H VERLAG GMBH

Status:
Published

DOI:
10.1002/chem.202202114 – link to the publication
The oligonucleotides containing N7-regioisomer of guanosine. Influence on thermodynamic properties and structure of RNA duplexes.

Authors:
A. Jarmołowicz, N. Dutta, W. Andrałojć, J. Sarzyńska, G. Framski, D. Baranowski, J. Boryski, A. Lahiri, Z. Gdaniec, E. Kierzek, R. Kierzek

Academic press:
RNA Journal (year: 2025, volume: 31, pages: 86–99), Publisher: Cold Spring Harbor Laboratory Press

Status:
Published

DOI:
10.1261/rna.080106.124 – link to the publication

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