Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Comprehensive characteristics of the microenvironment of borderline, low-grade and high-grade serous ovarian tumors in the clinico-pathological context, based on next generation sequencing

2020/37/B/NZ5/04215

Keywords:

lncRNA ovarian cancer borderline tumors tumor microenvironment NGS CRISPR/Cas9 IHC

Descriptors:

  • NZ5_003:
  • NZ5_007:
  • NZ1_001:

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Narodowy lnstytut Onkologii im. Marii Skłodowskiej-Curie - Państwowy lnstytut Badawczy

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Łukasz Michał Szafron 

Number of co-investigators in the project: 7

Call: OPUS 19 - announced on 2020-03-16

Amount awarded: 1 233 600 PLN

Project start date (Y-m-d): 2021-02-01

Project end date (Y-m-d): 2025-09-30

Project duration:: 56 months (the same as in the proposal)

Project status: Pending project

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  1. The Clinical Significance of CRNDE Gene Methylation, Polymorphisms, and CRNDEP Micropeptide Expression in Ovarian Tumors
    Authors:
    Szafron LA, Iwanicka-Nowicka R, Podgorska A, Bonna AM, Sobiczewski P, Kupryjanczyk J, Szafron LM.
    Academic press:
    International Journal of Molecular Sciences (rok: 2024, tom: 25, strony: 45680), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms25147531 - link to the publication
  2. The Diversity of Methylation Patterns in Serous Borderline Ovarian Tumors and Serous Ovarian Carcinomas
    Authors:
    Szafron LA, Iwanicka-Nowicka R, Sobiczewski P, Koblowska M, Dansonka-Mieszkowska A, Kupryjanczyk J, Szafron LM.
    Academic press:
    Cancers (rok: 2024, tom: 16, strony: 45684), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers16203524 - link to the publication
  3. A Multi-Faceted Analysis Showing CRNDE Transcripts and a Recently Confirmed Micropeptide as Important Players in Ovarian Carcinogenesis
    Authors:
    Balcerak A, Szafron LA, Rubel T, Swiderska B, Bonna AM, Konarzewska M, Sołtyszewski I, Kupryjanczyk J, Szafron LM.
    Academic press:
    International Journal of Molecular Sciences (rok: 2024, tom: 25, strony: 45685), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms25084381 - link to the publication
  4. An Analysis of Genetic Polymorphisms in 76 Genes Related to the Development of Ovarian Tumors of Different Aggressiveness
    Authors:
    Szafron LA, Sobiczewski P, Dansonka-Mieszkowska A, Kupryjanczyk J, Szafron LM.
    Academic press:
    International Journal of Molecular Sciences (rok: 2024, tom: 25, strony: 45683), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms252010876 - link to the publication

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