Transcriptional and functional characterization of invasive breast cancercells i

Transcriptional and functional characterization of invasive breast cancercells isolated using novel in vivo reporter system.

2020/37/B/NZ5/03950

Keywords

Descriptors

NZ5_005: Diagnostyka chorób człowieka
NZ5_007: Leczenie chorób człowieka
NZ5_003: Patogeneza chorób człowieka

Panel

NZ5 – Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr hab. Agnieszka Kobielak

Number of co-investigators in the project: 6

Call

OPUS 19 – announced on 2020-03-16

Amount awarded: 3 222 480 PLN
Project start date: 2021-01-22
Project end date: 2026-04-21
Project duration: 63 months (the same as in the proposal)
Project status: Project completed

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (3)

Catulin Based Reporter System to Track and Characterize the Population of Invasive Cancer Cells in the Head and Neck Squamous Cell Carcinoma

Authors:
Karpińska K, Gielata M, Gwiazdowska A, Boryń Ł, Kobielak A.

Academic press:
International Journal of Molecular Sciences (year: 2021, volume: 23(1), pages: 140), Publisher: MDPI

Status:
Published

DOI:
10.3390/ijms23010140 – link to the publication
Emerging Roles of the α-Catenin Family Member α-Catulin in Development, Homeostasis and Cancer Progression.

Authors:
Gielata M, Karpińska K, Pieczonka T, Kobielak A

Academic press:
International Journal of Molecular Sciences (year: 2022, volume: 23(19), pages: 11962), Publisher: MDPI

Status:
Published

DOI:
10.3390/ijms231911962 – link to the publication
Catulin reporter marks a heterogeneous population of invasive breast cancer cells with some demonstrating plasticity and participating in vascular mimicry.

Authors:
Gielata M, Karpińska K, Gwiazdowska A, Boryń Ł, Kobielak A.

Academic press:
Scientific Reports (year: 2022, volume: 12, pages: 12673), Publisher: Nature

Status:
Published

DOI:
10.1038/s41598-022-16802-2 – link to the publication

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