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Information on the principal investigator and host institution

Information of the project and the call

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Evaluation of the apelinergic system role in the doxorubicin-induced cardiotoxicity in the animal model.

2020/37/B/NZ5/02529

Keywords:

cardiotoxicity doxorubicin heart failure apelin elabela

Descriptors:

  • NZ5_004:
  • NZ4_004:
  • NZ2_002:

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Warszawski Uniwersytet Medyczny, Wydział Lekarski

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Agnieszka Barbara Cudnoch-Jędrzejewska 

Number of co-investigators in the project: 8

Call: OPUS 19 - announced on 2020-03-16

Amount awarded: 1 525 908 PLN

Project start date (Y-m-d): 2021-01-19

Project end date (Y-m-d): 2024-07-18

Project duration:: 42 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (3)
  1. Apelinergic System Affects Electrocardiographic Abnormalities Induced by Doxorubicin
    Authors:
    Buczma K, Borzuta H, Kamińska K, Sztechman D, Matusik K, Pawlonka J, Kowara M, Buchalska B, Cudnoch-Jędrzejewska A
    Academic press:
    Biomedicines (rok: 2025, tom: 13(1), strony: 46039), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/biomedicines13010094 - link to the publication
  2. Elabela Attenuates Doxorubicin-Induced Oxidative DNA Damage and Apoptosis in Rat Left Ventricular Myocardium
    Authors:
    Matusik K, Kamińska K, Janiuk I, Kasarełło K, Owe-Larsson M, Dylko D, Cudnoch-Jędrzejewska A.
    Academic press:
    Biomedicines (rok: 2025, tom: 13(10), strony: 2407), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/biomedicines13102407 - link to the publication
  3. Differential effects of apelin-13 on lipid peroxidation and DNA oxidation in doxorubicin-treated rats: A preliminary study
    Authors:
    Matusik K, Kamińska K, Kasarełło K, Cudnoch-Jędrzejewska A.
    Academic press:
    Biomolecules and Biomedicine (rok: 2025, tom: 26(6), strony: 1017-1019), Wydawca: ABMSFB&H
    Status:
    Published
    DOI:
    10.17305/bb.2025.13217. - link to the publication

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