Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Gamma-glutamylcysteine ligase participation in the antioxidant mechanism of action of sulodexide on vascular endothelial cell - the in vitro research

2019/35/N/NZ7/03071

Keywords:

endothelial dysfunction sulodexide gamma-glutamylcysteine ligase

Descriptors:

  • NZ7_014:

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Medycznych w Katowicach

woj. śląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Klaudia Katarzyna Bontor 

Number of co-investigators in the project: 2

Call: PRELUDIUM 18 - announced on 2019-09-16

Amount awarded: 69 900 PLN

Project start date (Y-m-d): 2020-08-20

Project end date (Y-m-d): 2023-08-19

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (2)
  1. Sulodexide Increases Glutathione Synthesis and Causes Pro-Reducing Shift in Glutathione-Redox State in HUVECs Exposed to Oxygen–Glucose Deprivation: Implication for Protection of Endothelium against Ischemic Injury
    Authors:
    Klaudia Bontor, Bożena Gabryel
    Academic press:
    Molecules , Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules27175465 - link to the publication
  2. Ligaza γ-glutamylocysteiny – od molekularnych mechanizmów regulacji aktywności enzymatycznej do implikacji terapeutycznych
    Authors:
    Bożena Gabryel, Klaudia Bontor
    Academic press:
    Postępy Higieny i Medycyny Doświadczalnej (), Wydawca: Sciendo
    Status:
    Published
    DOI:
    10.2478/ahem-2021-0013 - link to the publication