Projects funded by the NCN
Insulin – metallacarborane conjugates: A new strategy to enhance the biological efficacy of peptide drugs
2019/35/O/NZ7/03764
Keywords:
boron clusters metallacarboranes hybride molecules conjugates insulin peptide drugs
Descriptors:
- NZ7_016:
Panel:
NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology
Host institution :
Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk
woj. dolnośląskie
Principal investigator (from the host institution):
dr hab. Tomasz Marek Goszczyński
Number of co-investigators in the project: 2
Call: PRELUDIUM BIS 1 - announced on 2019-09-16
Amount awarded: 529 200 PLN
Project start date (Y-m-d): 2020-10-01
Project end date (Y-m-d): 2024-09-30
Project duration:: 48 months (the same as in the proposal)
Project status: Project completed
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (2)
- Supramolecular chemistry of anionic boron clusters and its applications in biologyAuthors:Jakub Cebula, Krzysztof Fink, Janusz Boratyński, Tomasz M. GoszczyńskiAcademic press:Coordination Chemistry Reviews (rok: 2023, tom: 477, strony: 214940), Wydawca: ElsevierStatus:PublishedDOI:10.1016/j.ccr.2022.214940 - link to the publication
- Structural Patterns Enhancing the Antibacterial Activity of Metallacarborane-Based AntibioticsAuthors:Jakub Cebula, Krzysztof Fink, Waldemar Goldeman, Bożena Szermer-Olearnik, Anna Nasulewicz-Goldeman, Mateusz Psurski, Monika Cuprych, Anna Kędziora, Bartłomiej Dudek, Gabriela Bugla-Płoskońska, Monika Chaszczewska-Markowska, Michalina Gos, Paweł Migdał and Tomasz M. GoszczyńskiAcademic press:Journal of Medicinal Chemistry (rok: 2023, tom: 66, strony: 14948-14962), Wydawca: ACSStatus:PublishedDOI:10.1021/acs.jmedchem.3c01516 - link to the publication