Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Reconstructing cardiovascular cell lineage evolution, one cell at a time

2019/35/B/NZ2/02548

Keywords:

zebrafish cardiovascular nkx2.5 cell lineage tracing single cell sequencing epigenetic CRISPR

Descriptors:

  • NZ2_002:
  • NZ3_012:

Panel:

NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution :

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej w Warszawie

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Cecilia Lanny Winata 

Number of co-investigators in the project: 5

Call: OPUS 18 - announced on 2019-09-16

Amount awarded: 2 631 552 PLN

Project start date (Y-m-d): 2020-10-01

Project end date (Y-m-d): 2025-09-30

Project duration:: 60 months (the same as in the proposal)

Project status: Pending project

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  1. scRNA-seq reveals the diversity of the developing cardiac cell lineage and molecular players in heart rhythm regulation.
    Authors:
    Abu Nahia K, Sulej A, Migdał M, Ochocka N, Ho R, Kamińska B, Zagorski M, Winata CL.
    Academic press:
    iScience (rok: 2024, tom: 27, strony: 45679), Wydawca: Elsevier
    Status:
    Published
  2. Protocol for the preparation of zebrafish whole heart cell suspension for single-cell analyses.
    Authors:
    Abu Nahia K, Winata CL.
    Academic press:
    STAR Protocols (rok: 2025, tom: 6, strony: 45668), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.xpro.2024.103586 - link to the publication
  3. Computational analysis of congenital heart disease associated SNPs: unveiling their impact on the gene regulatory system.
    Authors:
    Vashisht S, Parisi C, Winata CL.
    Academic press:
    BMC Genomics (rok: 2025, tom: 26, strony: 45674), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1186/s12864-025-11232-6 - link to the publication
  4. scRNA-seq reveals the diversity of the developing cardiac cell lineage and molecular players in heart rhythm regulation.
    Authors:
    Abu Nahia K, Sulej A, Migdał M, Ochocka N, Ho R, Kamińska B, Zagorski M, Winata CL.
    Academic press:
    iScience (rok: 2024, tom: 27, strony: 45679), Wydawca: Elsevier
    Status:
    Published