Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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PhageScan: identification of major phage epitopes affecting human health

2019/35/B/NZ7/01824

Keywords:

bacteriophages phages phageome microbiome immune response antibodies phage therapy human health

Descriptors:

  • NZ7_012:
  • NZ7_016:

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Krystyna Dąbrowska 

Number of co-investigators in the project: 6

Call: OPUS 18 - announced on 2019-09-16

Amount awarded: 2 361 600 PLN

Project start date (Y-m-d): 2020-06-25

Project end date (Y-m-d): 2025-06-24

Project duration:: 60 months (the same as in the proposal)

Project status: Project completed

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  • Book publications / chapters in book publications (1)
  1. Endocytosis of Bacteriophages
    Authors:
    Paulina Miernikiewicz, Krystyna Dąbrowska
    Academic press:
    Current Opinion in Virology (rok: 2022, tom: 52, strony: 229-235), Wydawca: ELSEVIER
    Status:
    Published
    DOI:
    10.1016/j.coviro.2021.12.009 - link to the publication
  2. Evolution of the T4 phage virion is driven by selection pressure from non-bacterial factors
    Authors:
    Joanna Majewska, Paulina Miernikiewicz, Aleksander Szymczak, Zuzanna Kaźmierczak, Tomasz M. Goszczyński, Barbara Owczarek, Izabela Rybicka, Jarosław Ciekot, Krystyna Dąbrowska
    Academic press:
    Microbiology Spectrum (rok: 2023, tom: 11(5), strony: e00115-23), Wydawca: American Society for Microbiology
    Status:
    Published
    DOI:
    10.1128/spectrum.00115-23 - link to the publication
  3. Evolution of the T4 phage virion is driven by selection pressure from non-bacterial factors
    Authors:
    Joanna Majewska, Paulina Miernikiewicz, Aleksander Szymczak, Zuzanna Kaźmierczak, Tomasz M. Goszczyński, Barbara Owczarek, Izabela Rybicka, Jarosław Ciekot, Krystyna Dąbrowska
    Academic press:
    Microbiology Spectrum (rok: 2023, tom: 11(5), strony: e00115-23), Wydawca: American Society for Microbiology
    Status:
    Published
    DOI:
    10.1128/spectrum.00115-23 - link to the publication
  4. Phage-specific antibodies
    Authors:
    Katarzyna Gembara, Krystyna Dąbrowska
    Academic press:
    Current Opinion in Biotechnology (rok: 2021, tom: 68, strony: 186-192), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.copbio.2020.11.011 - link to the publication
  1. Interaction of Bacteriophages with the Immune System: Induction of Bacteriophage-Specific Antibodies
    Authors:
    Katarzyna Gembara, Krystyna Dąbrowska
    Book:
    Bacteriophage Therapy, From Lab to Clinical Practice (rok: 2024, tom: 2734, strony: 183-196), Wydawca: Springer Protocols, Humana Press
    Status:
    Published
    DOI:
    10.1007/978-1-0716-3523-0_12. - link to the publication

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